Results 1 to 10 of about 3,134 (146)

Taï Forest Virus Does Not Cause Lethal Disease in Ferrets [PDF]

Microorganisms, 2021
Filoviruses are zoonotic, negative-sense RNA viruses, most of which are capable of causing severe disease in humans and nonhuman primates, often with high case fatality rates.
Zachary Schiffman, Feihu Yan, Shihua He, Kevin Tierney, Wenjun Zhu, Karla Emeterio, Huajun Zhang, Logan Banadyga, Xiangguo Qiu   +8 more
doaj   +2 more sources

Single-dose VSV-based vaccine protects cynomolgus macaques from disease after Taï Forest virus infection [PDF]

Emerging Microbes and Infections, 2023
Taï Forest virus (TAFV) is a lesser-known ebolavirus that causes lethal infections in chimpanzees and is responsible for a single human case. Limited research has been done on this human pathogen; however, with the recent emergence of filoviruses in West
Paige Fletcher, Kyle L. O’Donnell, Brianna M. Doratt, Delphine C. Malherbe, Chad S. Clancy, Joseph F. Rhoderick, Friederike Feldmann, Patrick W. Hanley, Thomas G. Ksiazek, Thomas W. Geisbert, Ilhem Messaoudi, Andrea Marzi   +11 more
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Mucosal Taï Forest virus infection causes disease in ferrets. [PDF]

PLoS Pathogens
The filovirus Taï Forest virus (TAFV) caused a single human case of infection originating from a chimpanzee outbreak, demonstrating that humans are susceptible to TAFV infection.
Paige Fletcher, Kyle L O'Donnell, Joseph F Rhoderick, Corey W Henderson, Atsushi Okumura, Trenton Bushmaker, Kathleen Cordova, Greg Saturday, Andrea Marzi   +8 more
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Pathogenic differences of cynomolgus macaques after Taï Forest virus infection depend on the viral stock propagation. [PDF]

PLoS Pathogens
Taï Forest virus (TAFV) is a negative-sense RNA virus in the Filoviridae family. TAFV has caused only a single human infection, but several disease outbreaks in chimpanzees have been linked to this virus.
Paige Fletcher, Chad S Clancy, Kyle L O'Donnell, Brianna M Doratt, Delphine C Malherbe, Joseph F Rhoderick, Friederike Feldmann, Patrick W Hanley, Ayato Takada, Ilhem Messaoudi, Andrea Marzi   +10 more
doaj   +2 more sources

Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity

Virulence, 2021
Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus, causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%.
Satoko Yamaoka, Hideki Ebihara
doaj   +1 more source

One-Step Reverse-Transcription FRET-PCR for Differential Detection of Five Ebolavirus Species. [PDF]

PLoS ONE, 2015
Ebola is an emerging infectious disease caused by a deadly virus belonging to the family Filoviridae, genus Ebolavirus. Based on their geographical distribution, Ebolavirus has been classified into total five species so far, mainly Zaire, Sudan, Taï ...
Guangwu Lu, Jilei Zhang, Chuntao Zhang, Xiaolu Li, Dawei Shi, Zhaopeng Yang, Chengming Wang   +6 more
doaj   +1 more source

Species-specific quantification of circulating ebolavirus burden using VP40-derived peptide variants.

PLoS Pathogens, 2021
Six ebolavirus species are reported to date, including human pathogens Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV), and Taï Forest virus (TAFV); non-human pathogen Reston virus (RESTV); and the plausible Bombali virus (BOMV).
Qingbo Shu, Tara Kenny, Jia Fan, Christopher J Lyon, Lisa H Cazares, Tony Y Hu   +5 more
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Ébola, lo que debemos saber

Revista Ciencias Biomédicas, 2020
La entidad conocida como ébola, recibe esa denominación por el nombre del río más cercano al distrito africano, donde se presentaron los primeros casos del brote en la década de los setenta del siglo XX (1).
Comité Editorial
doaj   +1 more source

Viral RNA Metagenomics of Hyalomma Ticks Collected from Dromedary Camels in Makkah Province, Saudi Arabia

Viruses, 2021
Arthropod-borne infections are a medical and economic threat to humans and livestock. Over the last three decades, several unprecedented viral outbreaks have been recorded in the Western part of the Arabian Peninsula.
Fathiah Zakham, Aishah E. Albalawi, Abdullah D. Alanazi, Phuoc Truong Nguyen, Abdulaziz S. Alouffi, Altaf Alaoui, Tarja Sironen, Teemu Smura, Olli Vapalahti   +8 more
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First-in-human study to evaluate safety, tolerability, and immunogenicity of heterologous regimens using the multivalent filovirus vaccines Ad26.Filo and MVA-BN-Filo administered in different sequences and schedules: A randomized, controlled study.

PLoS ONE, 2022
BackgroundThough clinically similar, Ebola virus disease and Marburg virus disease are caused by different viruses. Of the 30 documented outbreaks of these diseases in sub-Saharan Africa, eight were major outbreaks (≥200 cases; five caused by Zaire ...
Viki Bockstal, Georgi Shukarev, Chelsea McLean, Neil Goldstein, Stephan Bart, Auguste Gaddah, Dickson Anumenden, Jeroen N Stoop, Anne Marit de Groot, Maria G Pau, Jenny Hendriks, Stephen C De Rosa, Kristen W Cohen, M Juliana McElrath, Benoit Callendret, Kerstin Luhn, Macaya Douoguih, Cynthia Robinson   +17 more
doaj   +2 more sources