Results 51 to 60 of about 4,888 (209)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Functional and molecular characterization of Tachykinins and tachykinin receptors in the mouse uterus

, 2005
The aim of this study was to analyze the function and expression of tachykinins, tachykinin receptors, and neprilysin (NEP) in the mouse uterus. A previous study showed that the uterotonic effects of substance P (SP), neurokinin A (NKA), and neurokinin B
Pennefather, Jocelyn N., Page, N., Story, Margot E., Candenas, M. Luz, Pennefather, J.N., Pintando, C.O., Patak, E., Candenas, M.L., Fleming, A., Page, Nigel M., Pintado, C. Oscar, Patak, Eva, Pinto Pérez, Francisco M., Fleming, Anna, Pinto, F.M., Story, M.E., Story, M. E., Page, N. M., Pinto, F. M., Pintado, C. O., Pennefather, J. N., Candenas, M. L.   +21 more
core   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Multiple tachykinins and their receptors characterized in the gastropod mollusk Pacific abalone: Expression, signaling cascades, and potential role in regulating lipid metabolism

Frontiers in Endocrinology, 2022
Tachykinin (TK) families, including the first neuropeptide substance P, have been intensively explored in bilaterians. Knowledge of signaling of TK receptors (TKRs) has enabled the comprehension of diverse physiological processes.
Seungheon Lee, Mi Ae Kim, Mi Ae Kim, Jong-Moon Park, Keunwan Park, Young Chang Sohn   +5 more
doaj   +1 more source

Bladder inflammatory transcriptome in response to tachykinins: Neurokinin 1 receptor-dependent genes and transcription regulatory elements

BMC Urology, 2007
Background Tachykinins (TK), such as substance P, and their neurokinin receptors which are ubiquitously expressed in the human urinary tract, represent an endogenous system regulating bladder inflammatory, immune responses, and visceral hypersensitivity.
Dozmorov Igor, Memet Sylvie, Vadigepalli Rajanikanth, Simpson Cindy, Saban Ricardo, Saban Marcia R   +5 more
doaj   +1 more source

A Tale of Two States: Similarities and Differences in Neuropeptide Signaling in Larval and Adult Drosophila

Journal of Comparative Neurology, Volume 534, Issue 10, October 2026.
Neurosecretory cells of the brain are mostly the same in larvae and adults of Drosophila melanogaster and they produce the same neuropeptides and peptide hormones (NPHs), yet their functional roles differ to a large extent between the two stages. Many other peptidergic neurons change both in numbers and function.
Dick R. Nässel
wiley   +1 more source

Tachykinins and excitotoxicity in cerebellar granule cells

, 2006
The tachykinins represent an important group of neuropeptides that are widely distributed both in the central and peripheral nervous system where they perform several functions connected with neuronal modulation, often in synergy with glutamate ...
ZONA, CRISTINA, Cristina Zona, Cinzia Severini, Severini, C   +3 more
core   +1 more source

Tachykinins and Kisspeptins in the Regulation of Human Male Fertility [PDF]

, 2019
Infertility is a global disease affecting one out of six couples of reproductive age in the world, with a male factor involved in half the cases. There is still much to know about the regulation of human male fertility and thus we decided to focus on two
Fernández Sánchez, Manuel, Candenas, M. Luz, Cristina González-Ravina, Candenas, Luz, Manuel Fernández-Sánchez, Santamaría-López, Esther, Blasco, Víctor, González Ravina, Cristina, Víctor Blasco, Pinto Pérez, Francisco M., Santamaría López, Esther, Francisco M. Pinto, González-Ravina, Cristina, Esther Santamaría-López, Fernández-Sánchez, Manuel, Pinto, Francisco M., Luz Candenas   +16 more
core   +1 more source

Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia

npj Parkinson's Disease, 2022
L-DOPA administration is the primary treatment for Parkinson’s disease (PD) but long-term administration is usually accompanied by hyperkinetic side-effects called L-DOPA-induced dyskinesia (LID). Signaling neuropeptides of the basal ganglia are affected
Heather Hulme, Elva Fridjonsdottir, Theodosia Vallianatou, Reza Shariatgorji, Anna Nilsson, Qin Li, Erwan Bezard, Per E. Andrén   +7 more
doaj   +1 more source

Proteomic profiling identifies candidate biomarkers for small intestinal neuroendocrine tumours G1 and G2

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Although small intestinal neuroendocrine tumours (SI‐NET) Grade 1 (G1) and 2 (G2) are often studied together, clinical course and response to treatment may differ. We hypothesized that these tumour groups express different markers in blood that may inform future treatment strategies. Blood from 107 SI‐NET patients (G1 n = 64, G2 n = 43) and 50
Malin Grönberg, Dimitrios Papantoniou, Eva Tiensuu Janson   +2 more
wiley   +1 more source