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British Journal of Pharmacology, 2009 Some of the next articles are maybe not open access.
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Tachykinins and tachykinin receptors: a growing family
Life Sciences, 2004The peptides of the tachykinin family are widely distributed within the mammalian peripheral and central nervous systems and play a well-recognized role as excitatory neurotransmitters. Currently, the concept that tachykinins act exclusively as neuropeptides is being challenged, since the best known members of the family, substance P, neurokinin A and ...
FRANCISCO M Pinto +2 more
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Clinica Chimica Acta, 2007
Originally discovered in the 1930s, tachykinins have been a subject of renewed interest. Antagonists to the tachykinin receptors have shown potential in the treatment of a variety of maladies including neurodegenerative disorders, heart disease, pain perception and malignancies.
Pranela Rameshwar
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Originally discovered in the 1930s, tachykinins have been a subject of renewed interest. Antagonists to the tachykinin receptors have shown potential in the treatment of a variety of maladies including neurodegenerative disorders, heart disease, pain perception and malignancies.
Pranela Rameshwar
exaly +3 more sources
Tachykinins and tachykinin receptors in bone
Microscopy Research and Technique, 2002AbstractTachykinins are neuropeptides that are widely distributed in the body and function as neurotransmitters and neuromodulators. Five tachykinin subtypes: substance P (SP), neurokinin A, neurokinin B, neuropeptide K, and neuropeptide γ; and three receptor subtypes: neurokinin‐1, ‐2, and ‐3 receptors, have been identified.
Tetsuya, Goto, Teruo, Tanaka
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Tachykinins and tachykinin receptors: effects in the genitourinary tract
Life Sciences, 2005Tachykinins (TKs) are a family of peptides involved in the central and peripheral regulation of urogenital functions through the stimulation of TK NK1, NK2 and NK3 receptors. At the urinary system level, TKs locally stimulate smooth muscle tone, ureteric peristalsis and bladder contractions, initiate neurogenic inflammation and trigger local and spinal
Candenas, M. Luz +5 more
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Tachykinins and Tachykinin Receptors: Structure and Activity Relationships
Current Medicinal Chemistry, 2004In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide number of peptides with neurotransmitter activity have been identified in the past few years. Among them, the tachykinins substance P (SP), neurokinin A (NKA) and neurokinin B (NKB) appear to act as mediators of nonadrenergic, noncholinergic (NANC) excitatory ...
T A, Almeida +6 more
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Tachykinins and tachykinin‐receptors in the rat pineal gland
European Journal of Neuroscience, 2005AbstractHigh‐pressure liquid chromatography of extracts of rat pineal glands, followed by radio immunological analysis with antibodies against tachykinins, demonstrated the presence of substance P, neurokinin A and neurokinin B in the superficial rat pineal gland.
Mukda, S +5 more
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Pharmacological Reviews, 2002
The tachykinin peptide family certainly represents one of the largest peptide families described in the animal organism. So far, more than 40 tachykinins have been isolated from invertebrate (insects, worms, and molluscs), protochordate, and vertebrate (skin, gastrointestinal tract, peripheral and central nervous system) tissues.
C. Severini +4 more
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The tachykinin peptide family certainly represents one of the largest peptide families described in the animal organism. So far, more than 40 tachykinins have been isolated from invertebrate (insects, worms, and molluscs), protochordate, and vertebrate (skin, gastrointestinal tract, peripheral and central nervous system) tissues.
C. Severini +4 more
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Tachykinins: receptor to effector
The International Journal of Biochemistry & Cell Biology, 1996Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert their effects by binding to specific receptors. These tachykinin receptors are divided into three types, designated NK1, NK2 and NK3, respectively.
A M, Khawaja, D F, Rogers
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