Results 11 to 20 of about 7,870 (219)
Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish [PDF]
Molecules, 2012 The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI ...
Bing Wang +7 more
doaj +3 more sources
Tanshinone I Inhibits Oxidative Stress-Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling. [PDF]
Front Pharmacol, 2021 Cardiovascular disease, a disease caused by many pathogenic factors, is one of the most common causes of death worldwide, and oxidative stress plays a major role in its pathophysiology. Tanshinone I (Tan I), a natural compound with cardiovascular protective effects, is one of the main active compounds extracted from Salvia miltiorrhiza.
Wu YT +11 more
europepmc +5 more sources
Analysis of the HD-Zip I transcription factor family in Salvia miltiorrhiza and functional research of SmHD-Zip12 in tanshinone synthesis [PDF]
PeerJ, 2023 Background The homeodomain-leucine zipper I (HD-Zip I) transcription factor is a plant-specific protein that plays an essential role in the abiotic stress response of plants.
Yanhong Bai +7 more
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Agronomy, 2023 The red root of Salvia miltiorrhiza Bunge, a famous traditional Chinese medicine (TCM), was caused by tanshinone in epidermis cells. In order to study the biological function of ncRNAs in the tanshinone synthesis, the expression patterns of mRNA and ...
Caicai Lin +4 more
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Anticancer Effect of Tanshinones on Female Breast Cancer and Gynecological Cancer
Frontiers in Pharmacology, 2022 Female breast cancer, ovarian cancer, cervical cancer, and endometrial cancer are the most common tumors and the most common causes of cancer-related mortality worldwide in women.
Zhou Jin +5 more
doaj +1 more source
Salvia columbariae contains tanshinones [PDF]
Evidence-Based Complementary and Alternative Medicine, 2005 Salvia columbariae (chia) was examined and found to contain miltionone II, cryptotanshinone and tanshinone IIA. These compounds may be of interest in the treatment of stroke and heart attack.
Adams, James D. +2 more
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Molecules, 2021 In this study; a spectrum–effect relationship analysis combined with a high-performance liquid chromatography–mass spectrometry (LC–MS) analysis was established to screen and identify active components that can inhibit thrombin and factor Xa (THR and FXa)
Xu Wang +6 more
doaj +1 more source
Biomedicines, 2021 Abnormal and excessive accumulation of lipid droplets within hepatic cells is the main feature of steatosis and nonalcoholic fatty liver disease (NAFLD) or metabolic-associated fatty liver disease (MAFLD).
Wan-Yun Gao +5 more
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Total Syntheses of Tanshinone-I, Tanshinone-II and Cryptotanshinone [PDF]
Bulletin of the Chemical Society of Japan, 1968 Abstract Total syntheses of tanshinone-II (II) and cryptotanshinone (III) from 3-methylbenzofuran-4, 7-quinone (X) and 6,6-dimethyl-l-vinylcyclohexene (IX), and of tanshinone-I (I) from quinone X and o-methylstyrene (XVIII) are described. Preliminary accounts for the Diels-Alder reaction of methoxybenzoquinone revealed that the effect of
Hiroshi Kakisawa, Yoshinobu Inouye
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Tanshinone I and Tanshinone IIA/B attenuate LPS-induced mastitis via regulating the NF-κB
Biomedicine & Pharmacotherapy, 2021 Mastitis is a common disease occurs in breast-feeding mothers, but published data are poor. This study aimed to study the effects of Tanshinones on treating mastitis.Clinical trials performed in 58 breast-feeding mothers were carried out. B-ultrasound and blood test were used to measure the size of breast mass and the change of blood cell counts.
Lili, Yang +6 more
openaire +2 more sources