Results 81 to 90 of about 373 (115)

Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome

Chinese Medicine
Background Polycystic ovary syndrome (PCOS) is a complex neuroendocrine disorder characterized by dysregulation of the hypothalamus. Both electroacupuncture (EA) and manual acupuncture (MA) have demonstrated therapeutic efficacy in the treatment of PCOS ...
Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu, Yi Feng   +9 more
doaj   +1 more source

Image_2_Connexin-43 Gap Junctions Are Responsible for the Hypothalamic Tanycyte-Coupled Network.TIF

, 2018
Tanycytes are hypothalamic radial glia-like cells that form the basal wall of the third ventricle (3V) where they sense glucose and modulate neighboring neuronal activity to control feeding behavior.
Sergio López (6007100), Gerald Seifert (226744), María Angeles García-Robles (6007109), Alejandra Palma (6007103), Antonia Recabal (6007094), Estefanía Tarifeño-Saldivia (553128), Camille Philippot (6007097), Teresa Caprile (5587115), Aline Timmermann (6007106), Christian Steinhäuser (226746), Roberto Elizondo-Vega (553133), Magdiel Salgado (553127)   +11 more
core   +1 more source

The neuropeptide secretin regulates blood glucose homeostasis via tanycyte-arcuate nucleus axis

Blood glucose homeostasis is critical for animal survival. Impairment in long-term blood glucose or energy homeostasis will unavoidably lead to many metabolic diseases like diabetes and obesity.
韦计安, Wei, Jian
core  

Oral Presentation

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

Tanycytic G6PT silencing prevents obesity induced by early postnatal overnutrition

Scientific Reports
Tanycytes are ependymal glial cells that express the glucose-6-phosphate transporter (G6PT), which facilitates the incorporation of phosphorylated glucose from the cytosol into the reticular lumen.
María José Barahona, Matías Vera, Carol Gajardo, Francisca López, Paul San Martín, Francisco Nualart   +5 more
doaj   +1 more source

Knocking down the neuronal lactate transporter MCT2 in the arcuate nucleus of female rats increases food intake and body weight

Scientific Reports
In the arcuate nucleus of the hypothalamus, tanycyte-neuron interactions regulate glucose homeostasis and feeding behavior. Previously, we reported that monocarboxylate transporters (MCT) 1 and 4 are localized in tanycytes, whereas MCT2 is present in ...
Alanis Coca, Sergio López, Patricio Órdenes, Vania Sepúlveda, Diego Cuevas, Andrés Villarroel, Javiera Álvarez-Indo, Patricia V. Burgos, Estefanía Tarifeño, Roberto Elizondo-Vega, María A García-Robles   +10 more
doaj   +1 more source

Editorial: Physiological and pathological aspects of GnRH neuron system development

Frontiers in Endocrinology, 2023
Konstantina Chachlaki, Konstantina Chachlaki, Konstantina Chachlaki, Roberto Oleari   +3 more
doaj   +1 more source

Hypothalamic tanycytes expressed GK and GKRP.

, 2014
A–F, Confocal microscopy analysis of immunofluorescence using anti-vimentin (green) and Topro-3 nuclear stain (blue). A–C, 40-μm slides of frontal rat hypothalamus showing vimentin expression in α and β-tanycytes.
Marcos Villagra (553132), Fernando Martínez (2485834), Estefanía Tarifeño-Saldivia (553128), María José Yañez (553131), Elena Uribe (553134), Patricio Ordenes (553129), Carola Millán (553130), María de los Angeles García-Robles (553135), Francisco Nualart (231550), Roberto Elizondo-Vega (553133), Magdiel Salgado (553127), Paula Llanos (231548)   +11 more
core   +1 more source

Table_1_Tanycyte-Independent Control of Hypothalamic Leptin Signaling.XLSX

, 2019
Leptin is secreted by adipocytes to regulate appetite and body weight. Recent studies have reported that tanycytes actively transport circulating leptin across the brain barrier into the hypothalamus, and are required for normal levels of hypothalamic ...
Dong Won Kim (2256052), Seth Blackshaw (1586), David Cha (3284922), Sooyeon Yoo (546470), Thanh V. Hoang (3334965)   +4 more
core   +1 more source

ESCHR: a hyperparameter-randomized ensemble approach for robust clustering across diverse datasets

Genome Biology
Clustering is widely used for single-cell analysis, but current methods are limited in accuracy, robustness, ease of use, and interpretability. To address these limitations, we developed an ensemble clustering method that outperforms other methods at ...
Sarah M. Goggin, Eli R. Zunder
doaj   +1 more source