Results 21 to 30 of about 10,998,800 (355)

Targeted therapy using engineered extracellular vesicles: principles and strategies for membrane modification

open access: yesJournal of Nanobiotechnology, 2023
Extracellular vesicles (EVs) are 30–150 nm membrane-bound vesicles naturally secreted by cells and play important roles in intercellular communication by delivering regulatory molecules such as proteins, lipids, nucleic acids and metabolites to recipient
Qisong Liu   +3 more
semanticscholar   +1 more source

Development of a quantitative methylation-specific droplet digital PCR assay for detecting Dickkopf-related protein 3

open access: yesBMC Research Notes, 2022
Objective The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diagnosis and progression.
Kenji Araki, Ai Kurosawa, Hiromi Kumon
doaj   +1 more source

Targeted Radionuclide Therapy [PDF]

open access: yesCancers, 2011
Targeted radiotherapy is an evolving and promising modality of cancer treatment. The killing of cancer cells is achieved with the use of biological vectors and appropriate radionuclides. Among the many advantages of this approach are its selectiveness in delivering the radiation to the target, relatively less severe and infrequent side effects, and the
Ersahin, Devrim   +2 more
openaire   +2 more sources

Targeted Therapy for Cancers: From Ongoing Clinical Trials to FDA-Approved Drugs

open access: yesInternational Journal of Molecular Sciences, 2023
The development of targeted therapies has revolutionized cancer treatment, offering improved efficacy with reduced side effects compared with traditional chemotherapy.
Ha Yeong Choi, Ji-Eun Chang
semanticscholar   +1 more source

A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]

open access: yes, 2015
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W   +2 more
core   +2 more sources

Glioma targeted therapy: insight into future of molecular approaches

open access: yesMolecular Cancer, 2022
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically, gliomas occur among all ages, more often seen in adults, which males are more susceptible than females.
Keyang Yang   +13 more
semanticscholar   +1 more source

OX40 and 4-1BB delineate distinct immune profiles in sarcoma

open access: yesOncoImmunology, 2022
Systemic relapse after radiotherapy and surgery is the major cause of disease-related mortality in sarcoma patients. Combining radiotherapy and immunotherapy is under investigation as a means to improve response rates.
MJ Melake   +16 more
doaj   +1 more source

Node-positive breast cancer: Which are the best chemotherapy regimens? [PDF]

open access: yes, 2008
Breast cancer-associated mortality has been significantly reduced since the 1990s, mainly because of early diagnosis and systemic therapeutic interventions.
Bauerfeind, Ingo   +5 more
core   +2 more sources

From ‘Targeted Therapy’ to Targeted Therapy [PDF]

open access: yesAnticancer Research, 2019
In early 2000, the term 'targeted therapy' became popular and was used to indicate all types of tyrosine kinase inhibitors (TKI). However, the term targeted therapy had been used much earlier. Targeting tumor metabolism was already considered as targeted therapy, with methotrexate and 5-fluorouracil as the most successful examples.
openaire   +3 more sources

Advances in targeted therapies IV [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2002
The papers brought together in this supplement of the Annals of the Rheumatic Diseases constitute summaries of presentations at the Sixth International Symposium on Advances in Targeted Therapies, which was held from 28 April to 2 May 2004. As such these presentations represent the state of the art on the biology of mechanisms of action and ...
Breedveld, F.C.   +2 more
openaire   +7 more sources

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