Results 21 to 30 of about 10,998,800 (355)
Extracellular vesicles (EVs) are 30–150 nm membrane-bound vesicles naturally secreted by cells and play important roles in intercellular communication by delivering regulatory molecules such as proteins, lipids, nucleic acids and metabolites to recipient
Qisong Liu +3 more
semanticscholar +1 more source
Objective The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diagnosis and progression.
Kenji Araki, Ai Kurosawa, Hiromi Kumon
doaj +1 more source
Targeted Radionuclide Therapy [PDF]
Targeted radiotherapy is an evolving and promising modality of cancer treatment. The killing of cancer cells is achieved with the use of biological vectors and appropriate radionuclides. Among the many advantages of this approach are its selectiveness in delivering the radiation to the target, relatively less severe and infrequent side effects, and the
Ersahin, Devrim +2 more
openaire +2 more sources
Targeted Therapy for Cancers: From Ongoing Clinical Trials to FDA-Approved Drugs
The development of targeted therapies has revolutionized cancer treatment, offering improved efficacy with reduced side effects compared with traditional chemotherapy.
Ha Yeong Choi, Ji-Eun Chang
semanticscholar +1 more source
A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W +2 more
core +2 more sources
Glioma targeted therapy: insight into future of molecular approaches
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically, gliomas occur among all ages, more often seen in adults, which males are more susceptible than females.
Keyang Yang +13 more
semanticscholar +1 more source
OX40 and 4-1BB delineate distinct immune profiles in sarcoma
Systemic relapse after radiotherapy and surgery is the major cause of disease-related mortality in sarcoma patients. Combining radiotherapy and immunotherapy is under investigation as a means to improve response rates.
MJ Melake +16 more
doaj +1 more source
Node-positive breast cancer: Which are the best chemotherapy regimens? [PDF]
Breast cancer-associated mortality has been significantly reduced since the 1990s, mainly because of early diagnosis and systemic therapeutic interventions.
Bauerfeind, Ingo +5 more
core +2 more sources
From ‘Targeted Therapy’ to Targeted Therapy [PDF]
In early 2000, the term 'targeted therapy' became popular and was used to indicate all types of tyrosine kinase inhibitors (TKI). However, the term targeted therapy had been used much earlier. Targeting tumor metabolism was already considered as targeted therapy, with methotrexate and 5-fluorouracil as the most successful examples.
openaire +3 more sources
Advances in targeted therapies IV [PDF]
The papers brought together in this supplement of the Annals of the Rheumatic Diseases constitute summaries of presentations at the Sixth International Symposium on Advances in Targeted Therapies, which was held from 28 April to 2 May 2004. As such these presentations represent the state of the art on the biology of mechanisms of action and ...
Breedveld, F.C. +2 more
openaire +7 more sources

