Results 11 to 20 of about 1,817,538 (306)
BMC Research Notes, 2022 Objective The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diagnosis and progression.
Kenji Araki, Ai Kurosawa, Hiromi Kumon
doaj +1 more source
Advances in targeted Alpha therapy for prostate cancer [PDF]
, 2019 BACKGROUND: Amongst therapeutic radiopharmaceuticals, targeted alpha therapy (TαT) can deliver potent and local radiation selectively to cancer cells as well as the tumor microenvironment and thereby control cancer while minimizing toxicity.
De Vincentis, G +11 more
core +2 more sources
From ‘Targeted Therapy’ to Targeted Therapy [PDF]
Anticancer Research, 2019 In early 2000, the term 'targeted therapy' became popular and was used to indicate all types of tyrosine kinase inhibitors (TKI). However, the term targeted therapy had been used much earlier. Targeting tumor metabolism was already considered as targeted therapy, with methotrexate and 5-fluorouracil as the most successful examples.
openaire +3 more sources
Advances in targeted therapies IV [PDF]
Annals of the Rheumatic Diseases, 2002 The papers brought together in this supplement of the Annals of the Rheumatic Diseases constitute summaries of presentations at the Sixth International Symposium on Advances in Targeted Therapies, which was held from 28 April to 2 May 2004. As such these presentations represent the state of the art on the biology of mechanisms of action and ...
Breedveld, F.C. +2 more
openaire +7 more sources
A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]
, 2015 Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W +2 more
core +2 more sources
OX40 and 4-1BB delineate distinct immune profiles in sarcoma
OncoImmunology, 2022 Systemic relapse after radiotherapy and surgery is the major cause of disease-related mortality in sarcoma patients. Combining radiotherapy and immunotherapy is under investigation as a means to improve response rates.
MJ Melake +16 more
doaj +1 more source
Functionalized MoS2 nanosheet-capped periodic mesoporous organosilicas as a multifunctional platform for synergistic targeted chemo-photothermal therapy [PDF]
, 2018 The combination of different therapies into a single platform has attracted increasing attention as a potential synergistic tumor treatment. Herein, the fabrication of a novel folate targeted system for chemo-photothermal therapy by using thioether ...
Bremner, David H. +7 more
core +2 more sources
Cell Death and Disease, 2022 Aggresome formation is a protective cellular response to counteract proteasome dysfunction by sequestering misfolded proteins and reducing proteotoxic stress.
Chenliang Zhang +5 more
doaj +1 more source
Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies
Frontiers in Cell and Developmental Biology, 2023 Introduction: The glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab has been licensed for treatment in follicular non-Hodgkin lymphoma and B-CLL following clinical trials demonstrating superior outcomes to standard of care treatment ...
Ester Fagnano +10 more
doaj +1 more source
Effects of RANKL-Targeted Therapy in Immunity and Cancer. [PDF]
, 2014 The role of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK system is well characterized within bone, where RANKL/RANK signaling mediates osteoclastogenesis and bone resorption.
Cheng, Michael L, Fong, Lawrence
core +2 more sources