Results 11 to 20 of about 1,156,734 (317)
From ‘targeted therapy’ to targeted therapy* [PDF]
Anticancer Research, 2019 In early 2000, the term ‘targeted therapy' became popular and was used to indicate all types of tyrosine kinase inhibitors (TKI). However, the term targeted therapy had been used much earlier. Targeting tumor metabolism was already considered as targeted
Peters, Godefridus J.
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Biologics: Targets and Therapy, 2014 Charles Forscher,1 Monica Mita,2 Robert Figlin3 1Sarcoma Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; 2Experimental Therapeutics Program, Samuel Oschin Comprehensive Cancer Institute, Cedars ...
Forscher C, Mita M, Figlin R
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Targeted Therapies for the Neurofibromatoses [PDF]
Cancers, 2021 Over the past several years, management of the tumors associated with the neurofibromatoses has been recognized to often require approaches that are distinct from their spontaneous counterparts. Focus has shifted to therapy aimed at minimizing symptoms given the risks of persistent, multiple tumors and new tumor growth.
Lauren D. Sanchez +2 more
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Advances in targeted therapies IV [PDF]
Annals of the Rheumatic Diseases, 2002 The papers brought together in this supplement of the Annals of the Rheumatic Diseases constitute summaries of presentations at the Sixth International Symposium on Advances in Targeted Therapies, which was held from 28 April to 2 May 2004. As such these presentations represent the state of the art on the biology of mechanisms of action and ...
Breedveld, F.C. +2 more
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Targeting in Cancer Therapies [PDF]
Medical Sciences, 2016 Drug developers recruit and combine principles, procedures and strategies from chemistry, pharmacology, nanotechnology and biotechnology, focusing on the generation of functional vehicles as nano-carriers of drugs for improved stability and enhanced intracellular delivery.[...]
Ramon Mangues +2 more
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Targeted therapy in lymphoma [PDF]
Journal of Hematology & Oncology, 2010 AbstractDiscovery of new treatments for lymphoma that prolong survival and are less toxic than currently available agents represents an urgent unmet need. We now have a better understanding of the molecular pathogenesis of lymphoma, such as aberrant signal transduction pathways, which have led to the discovery and development of targeted therapeutics ...
Cavalli Franco +3 more
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Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies
Frontiers in Cell and Developmental Biology, 2023 Introduction: The glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab has been licensed for treatment in follicular non-Hodgkin lymphoma and B-CLL following clinical trials demonstrating superior outcomes to standard of care treatment ...
Ester Fagnano +10 more
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Journal of Experimental & Clinical Cancer Research, 2019 Background Immunotherapeutic approaches designed to augment T and B cell mediated killing of tumor cells has met with clinical success in recent years suggesting tremendous potential for treatment in a broad spectrum of tumor types.
Lawrence H. Cheung +6 more
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Cancer Cell International, 2021 Background Tumor metastasis is one of the leading reasons of the dismal prognosis of hepatocellular carcinoma (HCC). Epithelial-mesenchymal transition (EMT) is closely associated with tumor metastasis including HCC.
Gongmin Zhu +3 more
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Survival Prediction in Gallbladder Cancer Using CT Based Machine Learning
Frontiers in Oncology, 2020 ObjectiveTo establish a classifier for accurately predicting the overall survival of gallbladder cancer (GBC) patients by analyzing pre-treatment CT images using machine learning technology.MethodsThis retrospective study included 141 patients with ...
Zefan Liu +7 more
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