Results 81 to 90 of about 49,724 (234)

Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3 [PDF]

open access: yesNature, 2007
TATA-box-binding protein (TBP)-related factor 3, TRF3 (also called TBP2), is a vertebrate-specific member of the TBP family that has a conserved carboxy-terminal region and DNA-binding domain virtually identical to that of TBP (ref. 1). TRF3 is highly expressed during embryonic development, and studies in zebrafish and Xenopus have shown that it is ...
Hart, Daniel O.   +3 more
openaire   +3 more sources

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina   +6 more
wiley   +1 more source

Dynamic interactions of TATA‐Box binding protein with promoters is regulated by GlcNAcylation

open access: yesThe FASEB Journal, 2015
O‐GlcNAcylation is a dynamic posttranslational modification tightly correlated to the concentration of UDP‐GlcNAc, the end product of the hexosamine biosynthetic pathway (HBP), which varies according nutritional factors. Through HBP activity and production of UDP‐GlcNAc, OGT senses nutrient availability and forward the signal to ...
Stéphan Hardivillé   +5 more
openaire   +1 more source

Binding Mechanisms of TATA Box-Binding Proteins: DNA Kinking is Stabilized by Specific Hydrogen Bonds [PDF]

open access: yesBiophysical Journal, 2000
One of the common mechanisms of DNA bending by minor groove-binding proteins is the insertion of protein side chains between basepair steps, exemplified in TBP (TATA box-binding protein)/DNA complexes. At the central basepair step of the TATA box TBP produces a noticeable decrease in twist and an increase in roll, while engaging in hydrogen bonds with ...
Pardo, Leonardo   +4 more
openaire   +2 more sources

Constitution and function of intergenic genome regions in cultivated versus annual wild soybean in China

open access: yesJournal of Integrative Plant Biology, EarlyView.
Three‐case restricted two‐stage multi‐locus multi‐allele genome‐wide association study identified main‐effect genes and detected the regulatory effects of intergenic loci on genes, enabling comprehensive dissection of the genic‐intergenic genetic system for quantitative traits and providing a strategy for studying their genetic basis.
Xiaoshuai Hao   +11 more
wiley   +1 more source

Glucocorticoid Receptor (GR) and Specificity Protein 1 (Sp1) or Sp3 Transactivate the Bovine Alphaherpesvirus 1 (BoHV-1)-Infected Cell Protein 0 Early Promoter

open access: yesViruses
Bovine alphaherpesvirus 1 (BoHV-1) acute infection leads to latently infected sensory neurons in trigeminal ganglia. During lytic infection, the immediate early expression of infected cell protein 0 (bICP0) and bICP4 is regulated by an immediate early ...
Sankha Hewawasam   +2 more
doaj   +1 more source

The ciliary neurotrophic factor induces Stat3 phosphorylation in distinctive cytotypes of organs involved in body metabolism: An immunohistochemical study

open access: yesJournal of Anatomy, EarlyView.
p‐STAT3‐positive cells in metabolically relevant peripheral organs and tissues from mice administered with recombinant CNTF (0.3 mg/kg). Abstract Administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight in both humans and experimental animals, where it also ameliorates hyperglycemia, hyperinsulinemia, and dyslipidemia ...
Chiara Galli   +6 more
wiley   +1 more source

Rapid regulation of protein activity in fission yeast

open access: yes, 2014
Background: The fission yeast Schizosaccharomyces pombe is widely-used as a model organism for the study of a broad range of eukaryotic cellular processes such as cell cycle, genome stability and cell morphology. Despite the availability of extensive set
Sharom, Jeffrey R.   +9 more
core   +1 more source

Selection and evaluation of potential reference genes for gene expression analysis in Avena fatua

open access: yesPlant Protection Science, 2019
Eight commonly used candidate reference genes, 18S ribosomal RNA (rRNA) (18S), 28S rRNA (28S), actin (ACT), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), elongation factor 1 alpha (EF1α), ribosomal protein L7 (RPL7), Alpha-tubulin (α-TUB), and TATA ...
Junjie Liu   +5 more
doaj   +1 more source

Regulatory Mechanism of CsMYB1‐CsMYB82/CsbHLH48‑CsCAD4 Model for Resistance Against Colletotrichum gloeosporioides in Camellia sinensis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Anthracnose caused by Colletotrichum gloeosporioides is a major threat to tea cultivation; however, the molecular mechanism underlying different resistance among tea cultivars remains unclear. We identified distinct expression patterns of CsMYB82 between anthracnose‐resistant and susceptible varieties after infection with anthracnose from ...
Rui Han   +14 more
wiley   +1 more source

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