Results 101 to 110 of about 45,863 (244)

Normalized frequency distribution profile of TATA-box with respect to TSS across monocots and dicots.

open access: yes, 2013
Panel A: Genome-wide positional distribution of TATA-box frequency profile across four dicots: Arabidopsis thaliana (Ath - solid navy blue), Glycine max (Gma-solid dark blue), Populus trichocarpa (Ptr –solid blue sapphire), and Vitis vinifera (Vvi -solid
Sunita Kumari (79016)   +1 more
core   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

A methyl-sensitive element induces bidirectional transcription in TATA-less CpG island-associated promoters.

open access: yesPLoS ONE, 2018
How TATA-less promoters such as those within CpG islands (CGI) control gene expression is still a subject of active research. Here, we have identified the "CGCG element", a ten-base pair motif with a consensus sequence of TCTCGCGAGA present in a group of
Amin Mahpour   +4 more
doaj   +1 more source

Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

open access: yesBMC Genomics, 2018
Background The progress of medicine, science, technology, education, and culture improves, year by year, quality of life and life expectancy of the populace.
Irina V. Chadaeva   +12 more
doaj   +1 more source

Electrophoretic mobility shift assay showing the interaction of wild type TsTBP1 pAT5 TATA-box probe.

open access: yes, 2015
A) Lane 1: Labeled dsDNA-32P probe without nuclear extract; lane 2: TsTBP1-pAT5 TATA-box interaction with T. solium nuclear extract; lanes 3, 4, and 5: competence with pAT5 TATA-box cold probe in a molar excess of 25X, 50X, and 100X, respectively; lane 6:
Ángel Zarain-Herzberg (821381)   +5 more
core   +1 more source

Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa

open access: yesThe FEBS Journal, EarlyView.
Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley   +1 more source

Cloning of high molecular weight gluten subunit promoter and study on its function in wheat

open access: yesBrazilian Archives of Biology and Technology, 2009
The aim of this work was to study the cloning and characterization of HMW-GS 1Dx2 promoter from Triticum aestivum. A 1050 bp partial promoter fragment including a putative TATA box and 5' encoding sequence of the gene was cloned by amplifying the ...
Jin Weibo   +3 more
doaj   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

open access: yesThe FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

2 DISTINCT FACTORS BIND TO THE RABBIT UTEROGLOBIN TATA-BOX REGION AND ARE REQUIRED FOR EFFICIENT TRANSCRIPTION

open access: yes, 1994
The rabbit uteroglobin gene is expressed in a variety of epithelial cell types like the lung Clara cells and the glandular and luminal epithelial cells of the endometrium.
Knapp, Stefan   +4 more
core   +1 more source

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina   +6 more
wiley   +1 more source

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