Results 121 to 130 of about 5,518 (179)

The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

Drug Design, Development and Therapy, 2016
Kuo-Hsuan Chang,1,* I-Cheng Chen,1,* Hsuan-Yuan Lin,2 Hsuan-Chiang Chen,2 Chih-Hsin Lin,1 Te-Hsien Lin,2 Yu-Ting Weng,1 Chih-Ying Chao,1 Yih-Ru Wu,1 Jung-Yaw Lin,2 Guey-Jen Lee-Chen,2 Chiung-Mei Chen1 1Department of Neurology, Chang Gung Memorial ...
Chang KH, Chen IC, Lin HY, Chen HC, Lin CH, Lin TH, Weng YT, Chao CY, Wu YR, Lin JY, Lee-Chen GJ, Chen CM   +11 more
doaj  

Review: Tauopathy in the retina and optic nerve: Does it shadow pathological changes in the brain?

, 2012
Tau protein's versatility lies in its functions within the central nervous system, including protein scaffolding and intracellular signaling. Tauopathy has been one of the most extensively studied neuropathologies among the neurodegenerative diseases ...
Chang, Raymond C C, Ho, Winglau, Leung, Yen, Tsang, Andrea Wing Ting, So, Kwok Fai, Chiu, Kin   +5 more
core  

Inhibition of beta-arrestin oligomerization in tauopathy

As disclosed herein, β-arrestin1 and β-arrestin2 levels are highly elevated in brains of FTLD-tau patients suggesting that both β-arrestin1 and β-arrestin2 are elevated in the brains of patients with AD and FLTD. The current work also shows that when
Woo, Jung A., Lewandowski, Eric, Liggett, Stephen Bryant, Kang, David E., Chen, Yu   +4 more
core  

Tau PET and tauopathies [PDF]

European Journal of Nuclear Medicine and Molecular Imaging, 2016
openaire   +3 more sources

Tauopathy

, 2019
Hao Chi, Tzu-Kang Sang, Hui-Yun Chang
openaire   +2 more sources

Correction: Reduction of the RNA binding protein TIA1 exacerbates neuroinflammation in tauopathy

Frontiers in Neuroscience
Chelsey Jenna LeBlang, Maria Medalla, Nicholas William Nicoletti, Emma Catherine Hays, James Zhao, Jenifer Shattuck, Anna Lourdes Cruz, Benjamin Wolozin, Benjamin Wolozin, Benjamin Wolozin, Jennifer Irene Luebke   +10 more
doaj   +1 more source

A larval zebrafish model of traumatic brain injury: optimizing the dose of neurotrauma for discovery of treatments and aetiology

Biology Open
Laszlo F. Locskai, Taylor Gill, Samantha A. W. Tan, Alexander H. Burton, Hadeel Alyenbaawi, Edward A. Burton, W. Ted Allison   +6 more
doaj   +1 more source

[Tauopathy].

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001
S, Kosaka, H, Takuma, H, Mori
openaire   +1 more source

Non-Rodent Genetic Animal Models for Studying Tauopathy: Review of Drosophila, Zebrafish, and C. elegans Models

International Journal of Molecular Sciences, 2021
Tauopathy refers to a group of progressive neurodegenerative diseases, including frontotemporal lobar degeneration and Alzheimer’s disease, which correlate with the malfunction of microtubule-associated protein Tau (MAPT) due to abnormal ...
Kweon Yu, Jeong-Soo Lee, Manivannan Subramanian   +2 more
exaly   +2 more sources

Broad activation of the Parkin pathway induces synaptic mitochondrial deficits in early tauopathy [PDF]

Brain, 2022
Mitochondrial defects are a hallmark of early pathophysiology in Alzheimer’s disease, with pathologically phosphorylated tau reported to induce mitochondrial toxicity.
Yu Young Jeong, Mingyang Zhang, Qian Cai
exaly   +3 more sources