Results 41 to 50 of about 146,987 (295)

Prognostic value of nicotinamide N-methyltransferase in human cancers: Evidence from a meta-analysis and database validation

Open Medicine, 2022
Previous studies indicated that dysregulated expression of nicotinamide N-methyltransferase (NNMT) contributed to the tumor progression and predicted poor prognosis in various cancers.
Dang Ling, Wang Yingdong
doaj   +1 more source

Identification of an immune-related signature for the prognosis of uveal melanoma [PDF]

International Journal of Ophthalmology, 2020
"AIM: To construct an immune-related prognostic signature (IPS) that can distinguish and predict prognosis in uveal melanoma (UM). METHODS: The transcriptomic data and clinicopathological information of 80 UM patients were extracted from the TCGA ...
Ying-Zi Li, Ying Huang, Xiang-Yang Deng, Chang-Sen Tu   +3 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

TREMSUCS-TCGA – an integrated workflow for the identification of biomarkers for treatment success

Journal of Integrative Bioinformatics
Many publicly available databases provide disease related data, that makes it possible to link genomic data to medical and meta-data. The cancer genome atlas (TCGA), for example, compiles tens of thousand of datasets covering a wide array of cancer types.
Balogh Gabor, Jorge Natasha, Dupain Célia, Kamal Maud, Servant Nicolas, Le Tourneau Christophe, Stadler Peter F., Bernhart Stephan H.   +7 more
doaj   +1 more source

DUS4L Silencing Suppresses Cell Proliferation and Promotes Apoptosis in Human Lung Adenocarcinoma Cell Line A549

Cancer Management and Research, 2020
Zheng Li,* Ci Yin,* Bin Li, Qi-Yao Yu, Wen-Jie Mao, Jie Li, Jun-Ping Lin, Yu-Qi Meng, Hai-Ming Feng, Tao Jing Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou 730030, China ...
Li Z, Yin C, Li B, Yu QY, Mao WJ, Li J, Lin JP, Meng YQ, Feng HM, Jing T   +9 more
doaj  

High Levels of Class I Major Histocompatibility Complex mRNA Are Present in Epstein–Barr Virus-Associated Gastric Adenocarcinomas

Cells, 2020
Epstein−Barr virus (EBV) is responsible for approximately 9% of stomach adenocarcinomas. EBV-encoded microRNAs have been reported as reducing the function of the class I major histocompatibility complex (MHC-I) antigen presentation apparatus, which
Farhad Ghasemi, Steven F. Gameiro, Tanner M. Tessier, Allison H. Maciver, Joe S. Mymryk   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The Prognostic Significance of the TEAD4 in Hepatocellular Carcinoma

International Journal of General Medicine, 2023
Liping Lei,1,2,* Jingjing Yang,1,* Hao Peng,1 Ruiyan Huang,1 Lichun Liang,1 Ruifang Liu,1 Jiangfa Li1 1Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Guilin Medical University, Guilin, 541001, People’s Republic of ...
Lei L, Yang J, Peng H, Huang R, Liang L, Liu R, Li J   +6 more
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The diagnostic and prognostic value of C1orf174 in colorectal cancer [PDF]

BioImpacts
Introduction: Colorectal cancer (CRC) is among the lethal cancers, indicating the need for the identification of novel biomarkers for the detection of patients in earlier stages.
Elham Nazari, Ghazaleh Khalili-Tanha, Ghazaleh Pourali, Fatemeh Khojasteh-Leylakoohi, Hanieh Azari, Mohammad Dashtiahangar, Hamid Fiuji, Zahra Yousefli, Alireza Asadnia, Mina Maftooh, Hamed Akbarzade, Mohammadreza Nassiri, Seyed Mahdi Hassanian, Gordon A Ferns, Godefridus J Peters, Elisa Giovannetti, Jyotsna Batra, Majid Khazaei, Amir Avan   +18 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source