Results 41 to 50 of about 184,470 (334)
A novel identified pyroptosis-related prognostic signature of colorectal cancer
Colorectal cancer (CRC), one of the most common malignancies worldwide, leads to abundant cancer-related mortalities annually. Pyroptosis, a new kind of programmed cell death, plays a critical role in immune response and tumor progression.
Chen Zheng, Zhaobang Tan
doaj +1 more source
A stacking ensemble deep learning approach to cancer type classification based on TCGA data
Cancer tumor classification based on morphological characteristics alone has been shown to have serious limitations. Breast, lung, colorectal, thyroid, and ovarian are the most commonly diagnosed cancers among women.
Mohanad Mohammed +4 more
semanticscholar +1 more source
ABSTRACT Next-generation sequencing results obtained to detect somatic mutations in human cancers can also be searched for viruses that contribute to cancer. Recently, human papillomavirus 18 RNA was detected in tumor types not typically associated with HPV infection.
openaire +3 more sources
TCGA Expedition: A Data Acquisition and Management System for TCGA Data
The Cancer Genome Atlas Project (TCGA) is a National Cancer Institute effort to profile at least 500 cases of 20 different tumor types using genomic platforms and to make these data, both raw and processed, available to all researchers. TCGA data are currently over 1.2 Petabyte in size and include whole genome sequence (WGS), whole exome sequence ...
Olga Medvedeva +14 more
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Biased data, biased AI: deep networks predict the acquisition site of TCGA images
Background Deep learning models applied to healthcare applications including digital pathology have been increasing their scope and importance in recent years.
Taher Dehkharghanian +7 more
semanticscholar +1 more source
The diagnostic and prognostic value of C1orf174 in colorectal cancer [PDF]
Introduction: Colorectal cancer (CRC) is among the lethal cancers, indicating the need for the identification of novel biomarkers for the detection of patients in earlier stages.
Elham Nazari +18 more
doaj +1 more source
MARCKS is a New Prognostic Biomarker in Hepatocellular Carcinoma
Haoran Lu,1,* Rou Zhao,2,* Qianqian Qin,3 Liyong Tang,1 Guodong Ma,1 Baoyu He,2 Jing Liang,2 Li Wei,2 Xutong Wang,2 Qingli Bie,2 Xuning Wang,4 Bin Zhang2,5 1Department of Hepatobiliary Surgery, Affiliated Hospital of Jining Medical University ...
Lu H +11 more
doaj
Tumor microenvironment (TME) plays a crucial role in the initiation and progression of lung adenocarcinoma (LUAD); however, there is still a challenge in understanding the dynamic modulation of the immune and stromal components in TME.
K. Bi, Xu-Ge Wei, Xiao-Xue Qin, Bo I Li
semanticscholar +1 more source
Antibodies targeting the co-inhibitory receptor programmed cell death 1 (PDCD1, best known as PD-1) or its main ligand CD274 (best known as PD-L1) have shown some activity in patients with metastatic triple-negative breast cancer (TNBC), especially in a ...
Karsten A. Pilones +7 more
doaj +1 more source
Dead or alive? Pitfall of survival analysis with TCGA datasets [PDF]
We often encounter situations in which data from the TCGA that have been analyzed in papers we read or reviewed cannot be reproduced, even when TCGA datasets are used, especially in survival analyses. Therefore, we attempted to confirm the data source for TCGA survival analysis and found that several websites used to analyze the survival data of TCGA ...
Masashi Idogawa +5 more
openaire +3 more sources

