Results 41 to 50 of about 184,470 (334)

A novel identified pyroptosis-related prognostic signature of colorectal cancer

open access: yesMathematical Biosciences and Engineering, 2021
Colorectal cancer (CRC), one of the most common malignancies worldwide, leads to abundant cancer-related mortalities annually. Pyroptosis, a new kind of programmed cell death, plays a critical role in immune response and tumor progression.
Chen Zheng, Zhaobang Tan
doaj   +1 more source

A stacking ensemble deep learning approach to cancer type classification based on TCGA data

open access: yesScientific Reports, 2021
Cancer tumor classification based on morphological characteristics alone has been shown to have serious limitations. Breast, lung, colorectal, thyroid, and ovarian are the most commonly diagnosed cancers among women.
Mohanad Mohammed   +4 more
semanticscholar   +1 more source

Zombies in TCGA [PDF]

open access: yesJournal of Virology, 2015
ABSTRACT Next-generation sequencing results obtained to detect somatic mutations in human cancers can also be searched for viruses that contribute to cancer. Recently, human papillomavirus 18 RNA was detected in tumor types not typically associated with HPV infection.
openaire   +3 more sources

TCGA Expedition: A Data Acquisition and Management System for TCGA Data

open access: yesPLOS ONE, 2016
The Cancer Genome Atlas Project (TCGA) is a National Cancer Institute effort to profile at least 500 cases of 20 different tumor types using genomic platforms and to make these data, both raw and processed, available to all researchers. TCGA data are currently over 1.2 Petabyte in size and include whole genome sequence (WGS), whole exome sequence ...
Olga Medvedeva   +14 more
openaire   +5 more sources

Biased data, biased AI: deep networks predict the acquisition site of TCGA images

open access: yesDiagnostic Pathology, 2021
Background Deep learning models applied to healthcare applications including digital pathology have been increasing their scope and importance in recent years.
Taher Dehkharghanian   +7 more
semanticscholar   +1 more source

The diagnostic and prognostic value of C1orf174 in colorectal cancer [PDF]

open access: yesBioImpacts
Introduction: Colorectal cancer (CRC) is among the lethal cancers, indicating the need for the identification of novel biomarkers for the detection of patients in earlier stages.
Elham Nazari   +18 more
doaj   +1 more source

MARCKS is a New Prognostic Biomarker in Hepatocellular Carcinoma

open access: yesInternational Journal of General Medicine, 2023
Haoran Lu,1,* Rou Zhao,2,* Qianqian Qin,3 Liyong Tang,1 Guodong Ma,1 Baoyu He,2 Jing Liang,2 Li Wei,2 Xutong Wang,2 Qingli Bie,2 Xuning Wang,4 Bin Zhang2,5 1Department of Hepatobiliary Surgery, Affiliated Hospital of Jining Medical University ...
Lu H   +11 more
doaj  

BTK Has Potential to Be a Prognostic Factor for Lung Adenocarcinoma and an Indicator for Tumor Microenvironment Remodeling: A Study Based on TCGA Data Mining

open access: yesFrontiers in Oncology, 2020
Tumor microenvironment (TME) plays a crucial role in the initiation and progression of lung adenocarcinoma (LUAD); however, there is still a challenge in understanding the dynamic modulation of the immune and stromal components in TME.
K. Bi, Xu-Ge Wei, Xiao-Xue Qin, Bo I Li
semanticscholar   +1 more source

Converging focal radiation and immunotherapy in a preclinical model of triple negative breast cancer: contribution of VISTA blockade

open access: yesOncoImmunology, 2020
Antibodies targeting the co-inhibitory receptor programmed cell death 1 (PDCD1, best known as PD-1) or its main ligand CD274 (best known as PD-L1) have shown some activity in patients with metastatic triple-negative breast cancer (TNBC), especially in a ...
Karsten A. Pilones   +7 more
doaj   +1 more source

Dead or alive? Pitfall of survival analysis with TCGA datasets [PDF]

open access: yesCancer Biology & Therapy, 2021
We often encounter situations in which data from the TCGA that have been analyzed in papers we read or reviewed cannot be reproduced, even when TCGA datasets are used, especially in survival analyses. Therefore, we attempted to confirm the data source for TCGA survival analysis and found that several websites used to analyze the survival data of TCGA ...
Masashi Idogawa   +5 more
openaire   +3 more sources

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