Results 51 to 60 of about 184,470 (334)

Bioinformatic Exploration for Prognostic Significance of Sphingolipid Metabolism-Related Genes in Invasive Ductal Carcinoma Using the Cancer Genome Atlas Cohort

open access: yesInternational Journal of General Medicine, 2021
Su-Jeong Kim,1,* Jae-Ho Lee,2,* Woo-Jae Park,1 Shin Kim3– 5 1Department of Biochemistry, College of Medicine, Gachon University, Yeonsu-gu, Incheon, 21999, Republic of Korea; 2Department of Anatomy, School of Medicine, Keimyung University, Dalseo-
Kim SJ, Lee JH, Park WJ, Kim S
doaj  

Development of prognostic signature based on immune-related genes in muscle-invasive bladder cancer: bioinformatics analysis of TCGA database

open access: yesAging, 2021
Background: Muscle-invasive bladder cancer (MIBC) with high tumor stages accounts for most bladder cancer patient mortality. Platinum-based chemotherapy provides insufficient survival benefits; however, immunotherapy is a promising option for MIBC ...
K. Jin   +8 more
semanticscholar   +1 more source

Reproduction of the Cancer Genome Atlas (TCGA) and Asian Cancer Research Group (ACRG) Gastric Cancer Molecular Classifications and Their Association with Clinicopathological Characteristics and Overall Survival in Moroccan Patients

open access: yesDisease Markers, 2021
Introduction The Cancer Genome Atlas (TCGA) project and Asian Cancer Research Group (ACRG) recently categorized gastric cancer into molecular subtypes. Nevertheless, these classification systems require high cost and sophisticated molecular technologies,
Jean Paul Nshizirungu   +15 more
semanticscholar   +1 more source

Identification of potential diagnostic and prognostic biomarkers for LUAD based on TCGA and GEO databases

open access: yesBioscience Reports, 2021
Accumulating evidence has demonstrated that gene alterations play a crucial role in LUAD development, progression, and prognosis. The present study aimed to identify the hub genes associated with LUAD.
Qiang-qiang Zheng   +2 more
semanticscholar   +1 more source

Establishment and Analysis of MicroRNA Prognostic Risk Model of Papillary Thyroid Carcinoma Based on TCGA Database

open access: yesZhongliu Fangzhi Yanjiu, 2020
Objective To construct a risk model for predicting the prognosis of papillary thyroid carcinoma (PTC) patients based on the expression of microRNAs (miRNA).
JIAO Zhaoshuang, ZHANG Huainian
doaj   +1 more source

Mining TCGA database for tumor mutation burden and their clinical significance in bladder cancer

open access: yesBioscience Reports, 2020
Background: Bladder cancer is the ninth most-common cancer worldwide and it is associated with high morbidity and mortality. Tumor mutational burden (TMB) is an emerging biomarker in cancer characterized by microsatellite instability.
J. Lv   +4 more
semanticscholar   +1 more source

Overexpressed PAQR4 predicts poor overall survival and construction of a prognostic nomogram based on PAQR family for hepatocellular carcinoma

open access: yesMathematical Biosciences and Engineering, 2022
Objective: We aimed to explore the expression and clinical prognostic significance of PAQR4 in hepatocellular carcinoma (HCC). Methods: We obtained the gene expression matrix and clinical data of HCC from the cancer genome atlas (TCGA) and ...
Caihao Qu   +4 more
doaj   +1 more source

TSVdb: a web-tool for TCGA splicing variants analysis [PDF]

open access: yesBMC Genomics, 2018
Collaborative projects such as The Cancer Genome Atlas (TCGA) have generated various -omics and clinical data on cancer. Many computational tools have been developed to facilitate the study of the molecular characterization of tumors using data from the TCGA.
Ting Duan   +6 more
openaire   +4 more sources

Identification of Hub Genes and Their Correlation With Immune Infiltration Cells in Hepatocellular Carcinoma Based on GEO and TCGA Databases

open access: yesFrontiers in Genetics, 2021
Hepatocellular carcinoma (HCC) is a primary liver cancer with extremely high mortality in worldwide. HCC is hard to diagnose and has a poor prognosis due to the less understanding of the molecular pathological mechanisms and the regulation mechanism on ...
Rui Huang   +9 more
semanticscholar   +1 more source

The Cancer Genome Atlas (TCGA) based m6A methylation-related genes predict prognosis in hepatocellular carcinoma

open access: yesBioengineered, 2020
The current study aims to investigate the significance of N6-methyladenosine (m6A) methylation-related genes in the clinical prognosis of hepatocellular carcinoma (HCC) using bioinformatics analyses based on The Cancer Genome Atlas (TCGA) database ...
Jun Liu   +6 more
semanticscholar   +1 more source

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