Results 181 to 190 of about 272,710 (333)

Lower TCR repertoire diversity in Traj18-deficient mice [PDF]

Nature Immunology, 2012
Romain, Bedel, Jennifer L, Matsuda, Manfred, Brigl, Janice, White, John, Kappler, Philippa, Marrack, Laurent, Gapin   +6 more
openaire   +2 more sources

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Structure and specificity of T cell receptor gamma/delta on major histocompatibility complex antigen-specific CD3+, CD4-, CD8- T lymphocytes. [PDF]

, 1988
Analyses of TCR-bearing murine and human T cells have defined a unique subpopulation of T cells that express the TCR-gamma/delta proteins. The specificity of TCR-gamma/delta T cells and their role in the immune response have not yet been elucidated. Here
Bluestone, JA, Cotterman, M, Cron, RQ, Houlden, BA, Matis, LA   +4 more
core  

SAT0033 TCR REPERTOIRE PROFILING OF SYNOVIAL FLUID OF HLA-B*27+ AND HLA-B*27- PATIENTS WITH PSORIATIC ARTHRITIS [PDF]

, 2019
Ekaterina A. Komech, Anastasia Koltakova, Alena Novikova, Е. Yu. Loginova, Т. В. Коротаева, Ivan V. Zvyagin   +5 more
openalex   +1 more source

Supplementary Fig. S1-S5 from TCR Repertoire Diversity of Peripheral PD-1⁺CD8⁺ T Cells Predicts Clinical Outcomes after Immunotherapy in Patients with Non–Small Cell Lung Cancer [PDF]

, 2023
Jiefei Han, Jianchun Duan, Hua Bai, Yuqi Wang, Rui Wan, Xin Wang, Si Chen, Yanhua Tian, Di Wang, Kailun Fei, Zhuoran Yao, Shuhang Wang, Zhimin Lu, Zhijie Wang, Jie Wang   +14 more
openalex   +1 more source

Dynamic T‐Cell Reprogramming Modulates the Treatment Outcome of Neoadjuvant Immunochemotherapy in Non‐Small‐Cell Lung Cancer

MedComm, Volume 7, Issue 4, April 2026.
We explored the responding mechanisms associated with pathological responsiveness to neoadjuvant immunochemotherapy. CD8+ T‐cell subsets, including effect memory T (Tem), effector T (Teff), resident memory T (Trm), as well as exhausted T cells (Tex), showed higher clonality and diversity in responders, and both novel and pre‐existing clonal expansion ...
Rui Jin, Anhao Tian, Weina Lu, Qiyuan Wang, Xiuzhen Li, Sai Zhang, Guanxin Xu, Kai Zhu, Peng Li, Jianan Li, Wei Chen, Weiwei Yin, Wen Li, Yang Xia   +13 more
wiley   +1 more source

Molecular Markers Distinguishing Early‐Stage Mycosis Fungoides From Atopic Dermatitis Skin Lesions

Experimental Dermatology, Volume 35, Issue 4, April 2026.
ABSTRACT Mycosis fungoides (MF) is the most common type of primary cutaneous T‐cell lymphoma, a disease characterized by malignant T cells that home to the skin. In early stages, clinical presentation is often indistinguishable from benign chronic inflammatory skin diseases such as atopic dermatitis (AD), posing a challenge for proper diagnosis and ...
Brandon D. Ng, Conor Whelan, Natalia Alkon, Agata Kurowski, Constanze Jonak, Patrick M. Brunner   +5 more
wiley   +1 more source

Unraveling the chicken T cell repertoire with enhanced genome annotation

Frontiers in Immunology
T cell receptor (TCR) repertoire sequencing has emerged as a powerful tool for understanding the diversity and functionality of T cells within the host immune system.
Simon P. Früh, Simon P. Früh, Martin A. Früh, Benedikt B. Kaufer, Thomas W. Göbel   +4 more
doaj   +1 more source

Author response: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

, 2019
Rebeca Jimeno, Marta Lebrusant‐Fernandez, Christian Margreitter, Beth Lucas, Natacha Veerapen, Gavin Kelly, Gurdyal S. Besra, Franca Fraternali, Jo Spencer, Graham Anderson, Patricia Barral   +10 more
openalex   +1 more source

Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach [PDF]

, 2015
Asquith, RE, Bangham, C, Laydon, D
core   +1 more source