Results 91 to 100 of about 546 (157)

Infect Dis Clin Pract (Baltim Md) [PDF]

Few antibiotic options exist for the management of infections due to vancomycin-resistant enterococci (VRE). We describe a case involving the safe and successful use of tedizolid, a new oxazolidinone, to treat VRE prosthetic joint infection.KM1 CA156708 ...

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Current Status and Perspectives of Antibacterial Agents Belonging to 2-Oxazolidinones

Pharmaceuticals
In the last three decades, 2-oxazolidinones have emerged as an important class of inhibitors of bacterial protein synthesis, effective in the treatment of multidrug-resistant (MDR) bacterial infections. From a public health perspective, the importance of
Jessica Ceramella, Annaluisa Mariconda, Domenico Iacopetta, Maria Marra, Alessia Catalano, Paola Checconi, Stefano Aquaro, Carmela Saturnino, Pasquale Longo, Maria Stefania Sinicropi   +9 more
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In Vitro Susceptibility Testing of Tedizolid against Isolates of Nocardia

, 2017
There is a paucity of efficacious antimicrobials (especially oral) against clinically relevant species of Nocardia . To date, all species of Nocardia have been susceptible to linezolid, the first ...
Richard J. Wallace, Barbara A. Brown-Elliott   +1 more
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Linezolid and tedizolid adverse effects: a review on serotonin syndrome, myelosuppression, neuropathies, and lactic acidosis

Antimicrobial Stewardship & Healthcare Epidemiology
Oxazolidinone antibiotics—linezolid and tedizolid—are often used to treat multidrug-resistant infections. They are highly bioavailable and ideal for transition to enteral therapy when appropriate.
Adam Greenfield, Erin Deja, Kimberly Lee, Sangeeta Sastry, Barry Rittmann   +4 more
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In vitro activity of tedizolid and linezolid against Staphylococcus epidermidis isolated from prosthetic joint infections

, 2017
Prosthetic joint infections (PJIs) are rare but long-lasting and are serious complications without any spontaneous resolution, requiring additional surgery and long-term treatment with antibiotics. Staphylococci are the most important aetiological agents
Hellmark, B,, Nilsdotter-Augustinsson, Åsa,, Nilsdotter-Augustinsson, Åsa, Å. Nilsdotter-Augustinsson, Hellmark, B, B. Hellmark, Littorin, C,, Littorin, C, C. Littorin, B. Söderquist, Söderquist, Bo,, Littorin, C.,, Hellmark, Bengt,, Söderquist, Bo   +13 more
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Current Problems of Infections Caused by MRSA and Ways to Address Them

Антибиотики и Химиотерапия, 2020
The increase in the growth rate of MRSA as an etiologic factor has been recorded worldwide in recent years. The main problem of antibiotic resistance in Staphylococcus aureus is its resistance to beta-lactam antibiotics.
S. K. Zyryanov, I. N. Sychev, Yu. Sh. Gushchina   +2 more
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Antibiotic Resistance to Molecules Commonly Prescribed for the Treatment of Antibiotic-Resistant Gram-Positive Pathogens: What Is Relevant for the Clinician?

Pathogens
Antibiotic resistance in Gram-positive pathogens is a relevant concern, particularly in the hospital setting. Several antibiotics are now available to treat these drug-resistant pathogens, such as daptomycin, dalbavancin, linezolid, tedizolid ...
Gianpiero Tebano, Irene Zaghi, Francesco Baldasso, Chiara Calgarini, Roberta Capozzi, Caterina Salvadori, Monica Cricca, Francesco Cristini   +7 more
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Efficacy of tedizolid against enterococci and staphylococci, including cfr+ strains, in a mouse peritonitis model

, 2019
In a mouse peritonitis model, tedizolid was comparable to linezolid and daptomycin against an Enterococcus faecium strain (VANr, AMPr), an Enterococcus faecalis strain, and a methicillin-resistant Staphylococcus aureus (MRSA) strain with and without cfr.
Murray, Barbara, Arias, Cesar A, Singh, Kavindra V.   +2 more
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Clinical safety and tolerability of tedizolid phosphate in the treatment of acute bacterial skin and skin structure infections.

, 2018
Click on the Resource Link to access the article (may not be free).BACKGROUND: We evaluated safety and tolerability of tedizolid phosphate at the 200-mg once-daily dose approved for 6-day treatment of skin and skin-structure infections. RESEARCH DESIGN
Bidell, Monique R, Prokocimer, Philippe, Hardalo, Cathy, De Anda, Carisa, Anuskiewicz, Steven, Lodise, Thomas P, Flanagan, Shawn D   +6 more
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Peripheral neuropathy during long-term suppressive therapy with tedizolid: a case series

International audienceAbstract Background and objectives Due to its potentially better long-term haematologic tolerance compared to linezolid, tedizolid represents an attractive option for prolonged antibiotic therapy in complicated/chronic Gram-positive
Conrad, Anne, Valour, Florent, Fessy, Michel, Horikian, Ani, Dupieux, Céline, Masson, Jean-Baptiste, Pibarot, Vincent, Chevreau-Ciliberti, Audrey, Boulant, Johanna, Walch, Arnaud, Mojallal, Alain-Ali, Kolenda, Camille, Lippman, Joanna-Isabelle Kurban Bessa, Maucotel, Anne-Lise, Garreau, Romain, Ducharne, Louis, Stacoffe, Nicolas, Colas, Antoine, Rouhana, Kaissar, Roux, Sandrine, Baltzer, Jean, Ader, Florence, Dziadzko, Mikhail, Batailler, Cécile, Derreveaux, Vianney, Druel, Thibault, Van-Den-Bogaart, Lorena, Wan, Marie, Triffault-Filit, Claire, Cance, Nicolas, Vézole, Léonard, Lherm, Mathilde, Macabéo, Caroline, Aubrun, Frédéric, Perpoint, Thomas, Martres, Sébastien, Cottin, Judith, Ewald, Fabien, Morelec, Isabelle, Besse, Jean-Luc, Henry, Agnes, Lahlali, Selma, Javaux, Clément, Bertani, Antoine, Rongieras, Frédéric, Erard, Julien, Gazarian, Aram, Braun, Evelyne, Person, Hélène, Pialat, Jean-Baptiste, Landre, Sophie, Trecourt, Alexis, Bahuaud, Olivier, Soueges, Sarah, Servien, Elvire, Gaillard, Christophe, Beraud, Laetitia, Ferry, Tristan, Lustig, Sébastien, Ben-Hadid, Nael, Henry, Guillaume, Ly, Lyliane, Delfosse, Gerald, Chaudier, Philippe, Viste, Anthony, Vanpoulle, Gaetan, Hashim, Abdulrahman, Beringheli, Tomaso, Simon, Marie, Curtil-Dit-Galin, Matthieu, Lavigne, Joris, Mesnard, Guillaume, Roussel-Gaillard, Tiphaine, Chauvelot, Pierre, Cotte, Matthieu, Rarchaert, Maxime, Couraudon, Alexandre, Vervust, Grégoire, Trouillet, Franck, Rasigade, Jean-Philippe, Cuinet, Thomas, Gunst, Stanislas, Goutelle, Sylvain, Vieux, Noémie, Becker, Agathe, Gicquel, David, Briot, Thomas, Eberl, Isabelle, Rutka, Victor   +88 more
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