Expert Opin Drug Metab Toxicol [PDF]
Introduction:Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI). Although tedizolid shares many similar properties with linezolid, another oxazolidinone used to treat ABSSSI, the two antibiotics have ...
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Tedizolid-Cyclodextrin System as Delayed-Release Drug Delivery with Antibacterial Activity
, 2020 Progressive increase in bacterial resistance has caused an urgent need to introduce new antibiotics, one of them being oxazolidinones with their representative tedizolid. Despite the broad spectrum of activity of the parent tedizolid, it is characterized
Judyta Cielecka-Piontek +7 more
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Oxidative stress is two‐sided in the treatment of acute myeloid leukemia
Cancer Medicine, Volume 13, Issue 9, May 2024.Abstract Introduction Oxidative stress caused by elevated ROS, as a novel therapeutic mechanism, has been implicated in various tumors including AML. AML cells are chronically under oxidative stress, yet overreliance on ROS production makes tumor cells increasingly vulnerable to further damage. Reducing the cytotoxic effect of ROS on normal cells while
Chenyang Fan +3 more
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Pharmacodynamic evidence for tedizolid use in Mycobacterium avium lung disease
IJTLD OpenOBJECTIVE: On guideline-based therapy for Mycobacterium avium complex (MAC) lung disease (LD), ∼50%–60% of patients suffer recalcitrant disease. Tedizolid is a promising agent based on the intracellular hollow fibre model of MAC-LD (HFS-MAC) using the ...
D. Deshpande, S. Srivastava, T. Gumbo
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Pulmonary nocardiosis treated with tedizolid.
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2019 -
José María Gutiérrez-Urbón +4 more
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Potential of the Introduction of Tedizolid for the Treatment of Complicated Skin and Soft Tissue Infections in a Russian Multi-Field Hospital [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2016 Increase in prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains among the pathogens of complicated skin and soft tissue infections (cSSTIs) in hospitalised patients demands introduction of new treatment options with improved efficacy
Belkova Yu.А. +5 more
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Infection and Drug Resistance, 2021 Lingbo Wang,1,* Ying Zhang,2,* Shixing Liu,1 Na Huang,1 Weiliang Zeng,1 Wenya Xu,1 Tieli Zhou,1 Mo Shen1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People’s ...
Wang L +7 more
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Comparative Efficacies of Tedizolid Phosphate, Vancomycin, and Daptomycin in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis [PDF]
, 2015 Tedizolid, the active component of the prodrug tedizolid phosphate, is a novel oxazolidinone that is approximately 4 times more active by weight than linezolid against Staphylococcus aureus in vitro.
Chan, Liana C +3 more
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Tedizolid: A comprehensive review of pharmacology, clinical applications and future directions in antimicrobial resistance [PDF]
Afro-Egyptian Journal of Infectious and Endemic DiseasesTedizolid phosphate, a second-generation xazolidinone, has emerged as a valuable tool in the treatment of Gram-positive bacterial infections, particularly those caused by multidrug-resistant organisms such as methicillin-resistant Staphylococcus aureus ...
Shambo Samajdar +7 more
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Acute bacterial skin and soft tissue infections: new drugs in ID armamentarium
Journal of Community Hospital Internal Medicine Perspectives, 2019 Acute bacterial skin and soft tissue infections (SSTI) are among the most common reasons for hospitalization of adults in the USA today. Cellulitis or SSTI can cause significant morbidity and mortality.
Raghavendra Tirupathi +4 more
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