Results 81 to 90 of about 3,270 (204)

Tedizolid-Rifampicin Combination Prevents Rifampicin-Resistance on in vitro Model of Staphylococcus aureus Mature Biofilm

open access: yesFrontiers in Microbiology, 2020
Staphylococcus aureus infections associated with implanted medical devices are difficult to treat and require long-lasting antibiotic therapies, especially when device removal is not possible or easy such as in the case of joint prostheses.
Anna Gidari   +6 more
doaj   +1 more source

Evaluation of uncomplicated acute respiratory tract infection management in veterans: A national utilization review. [PDF]

open access: yes, 2019
BackgroundAntibiotics are overprescribed for acute respiratory tract infections (ARIs). Guidelines provide criteria to determine which patients should receive antibiotics.
ARI Management Improvement Group   +8 more
core  

Dynamic distribution of systemically administered antibiotics in orthopeadically relevant target tissues and settings

open access: yesAPMIS, Volume 132, Issue 12, Page 992-1025, December 2024.
This review aimed to summarize the current literature on antibiotic distribution in orthopedically relevant tissues and settings where dynamic sampling methods have been used. PubMed and Embase databases were systematically searched. English‐published studies between 2004 and 2024 involving systemic antibiotic administration in orthopedically relevant ...
Maria Bech Damsgaard Nielsen   +5 more
wiley   +1 more source

Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection. [PDF]

open access: yes, 2019
Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. We investigated relevant phenotype differences between cfr-positive and -negative MRSA that contribute to pathogenesis, and the efficacy of linezolid-based combination ...
Li, Liang   +6 more
core  

Efficacy and safety of vancomycin compared with those of alternative treatments for methicillin‐resistant Staphylococcus aureus infections: An umbrella review

open access: yesJournal of Evidence-Based Medicine, Volume 17, Issue 4, Page 729-739, December 2024.
Abstract Objective To summarize the evidence on the efficacy and safety of vancomycin compared with those of alternative treatments in adult patients with methicillin‐resistant Staphylococcus aureus (MRSA) infection. Methods PubMed, Embase, and Web of Science were searched up to December 15, 2023, for systematic reviews and meta‐analyses comparing ...
Sujata Purja   +4 more
wiley   +1 more source

Non‐Reductive CO2 Valorization into Oxazolidinones via Cycloaddition to Aziridines: A Personal Insight

open access: yesEuropean Journal of Organic Chemistry, Volume 27, Issue 39, October 14, 2024.
This perspective provides an overview of recent homogeneous and heterogeneous catalytic methodologies published on the CO2 cycloaddition to aziridines to form oxazolidinones, with a particular attention to the employed experimental conditions, which are essential parameters for envisioning real costs and possible applications of these synthetic ...
Caterina Damiano   +3 more
wiley   +1 more source

Differences in oxazolidinone resistance mechanisms and small colony variants emergence of Staphylococcus aureus induced in an in vitro resistance development model

open access: yesEmerging Microbes and Infections
Invasive Staphylococcus aureus infections are associated with a high burden of disease, case fatality rate and healthcare costs. Oxazolidinones such as linezolid and tedizolid are considered potential treatment choices for conditions involving ...
Moritz Staudacher   +10 more
doaj   +1 more source

Pulmonary nocardiosis treated with tedizolid.

open access: yesFarmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2019
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José María Gutiérrez-Urbón   +4 more
openaire   +3 more sources

Oxidative stress is two‐sided in the treatment of acute myeloid leukemia

open access: yesCancer Medicine, Volume 13, Issue 9, May 2024.
Abstract Introduction Oxidative stress caused by elevated ROS, as a novel therapeutic mechanism, has been implicated in various tumors including AML. AML cells are chronically under oxidative stress, yet overreliance on ROS production makes tumor cells increasingly vulnerable to further damage. Reducing the cytotoxic effect of ROS on normal cells while
Chenyang Fan   +3 more
wiley   +1 more source

In vitro Antimicrobial Activity Comparison of Linezolid, Tedizolid, Sutezolid and Delpazolid Against Slowly Growing Mycobacteria Isolated in Beijing, China

open access: yesInfection and Drug Resistance, 2021
Xia Yu,* Fengmin Huo,* Fen Wang,* Shu’an Wen, Guanglu Jiang, Yi Xue, Lingling Dong, Liping Zhao, Rui Zhu, Hairong Huang National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory for Drug-Resistant Tuberculosis Research, Beijing ...
Yu X   +9 more
doaj  

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