Results 71 to 80 of about 2,247 (204)

Characterization of the haematological profile of 21 days of tedizolid in healthy subjects.

, 2016
Click on the Resource Link to access the article (may not be free).OBJECTIVES: Tedizolid is a novel oxazolidinone antibacterial. Oxazolidinones carry concerns for time-dependent myelosuppression. To further explore tedizolid's haematological tolerability,
Bidell, Monique R, Prokocimer, Philippe, Lodise, Thomas P, Flanagan, Shawn D, Minassian, Sonia L, Zasowski, Evan J   +5 more
core   +1 more source

Acanthamoeba Infection in a Hematopoietic Cell Transplant Recipient: Challenges in Diagnosis, Management, and Source Identification

Transplant Infectious Disease, Volume 27, Issue 1, January/February 2025.
Acanthamoeba infection in HCT recipients, represent multiple challenges. Early diagnosis, and effective treatment, remain the main barriers to survival. High index of suspicion, may help in identifying cases earlier. Given its ubiquiteness, source identification remains challenging.
Camellia T. Banerjee, Sean Conlan, Anahita Mostaghim, Angela Michelin, Matthew Arduino, Mia Mattioli, Julia C. Haston, Sanchita Das, Amir Seyedmousavi, Bickey H. Chang, Elise M. O'Connell, Christopher G. Kanakry, Akbulut Dilara, Martha Quezado, Juan Gea‐Banacloche, Clay Deming, Julia A. Segre, Alison Han, Jennifer Cuellar‐Rodriguez   +18 more
wiley   +1 more source

Linezolid‐Induced Glossitis and Papillitis in Orthopedic Patients With Postoperative Infection: A Case Report

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Linezolid, an oxazolidinone antibiotic, is commonly used to treat Gram‐positive skin infections and has additional off‐label success in treating bone and soft tissue infections. Linezolid has been associated with adverse effects, particularly those that are hematologic and neurologic in nature.
Ryan J. Blake, Benjamin M. Frye, Allison M. Lastinger, Rajib Chowdhury   +3 more
wiley   +1 more source

In vitro activity of tedizolid and linezolid against Staphylococcus epidermidis isolated from prosthetic joint infections [PDF]

, 2017
Prosthetic joint infections (PJIs) are rare but long-lasting and are serious complications without any spontaneous resolution, requiring additional surgery and long-term treatment with antibiotics. Staphylococci are the most important aetiological agents
Hellmark, B,, Nilsdotter-Augustinsson, Åsa,, Nilsdotter-Augustinsson, Åsa, Å. Nilsdotter-Augustinsson, Hellmark, B, B. Hellmark, Littorin, C,, Littorin, C, C. Littorin, B. Söderquist, Söderquist, Bo,, Littorin, C.,, Hellmark, Bengt,, Söderquist, Bo   +13 more
core   +2 more sources

Tedizolid-Rifampicin Combination Prevents Rifampicin-Resistance on in vitro Model of Staphylococcus aureus Mature Biofilm

Frontiers in Microbiology, 2020
Staphylococcus aureus infections associated with implanted medical devices are difficult to treat and require long-lasting antibiotic therapies, especially when device removal is not possible or easy such as in the case of joint prostheses.
Anna Gidari, Samuele Sabbatini, Elisabetta Schiaroli, Stefano Perito, Daniela Francisci, Franco Baldelli, Claudia Monari   +6 more
doaj   +1 more source

Cochlear Implant Complicated by Nontuberculous Mycobacteria Infection: Report and Literature Review

Case Reports in Otolaryngology, Volume 2025, Issue 1, 2025.
Objective: Nontuberculosis mycobacteria (NTM) infection of cochlear implants are exceedingly rare. Here, we report one such case and review the literature surrounding previous reports. Methods: Case report. Case Report: A 76‐year‐old female underwent right cochlear implantation.
Haidee Chen, Erik B. Vanstrum, Rodell Santuray, Adam Xiao, Akira Ishiyama, M. Tayyar Kalcioglu   +5 more
wiley   +1 more source

A Tedizolid és a Linezolid In Vitro érzékenységének összehasonlító vizsgálata Vancomycin-rezisztens Enterococcus (VRE) törzsek esetében

, 2017
Háttér: A vancomycin rezisztens Enterococcusok (VRE) esetében új terápiás lehetőség a tedizolid-foszfát (Sivextro®), amely az oxazolidinonok csoportjába tartozik, hasonlóan a korábban már alkalmazott linezolidhoz.
Oszlánczi, Máté József
core  

Pharmacokinetics of Tedizolid and Pseudoephedrine Administered Alone or in Combination in Healthy Volunteers

, 2018
Therapeutic doses of tedizolid phosphate, an oxazolidinone antibiotic, lack monoamine oxidase inhibition in vivo, potentially resulting in an improved safety profile versus other oxazolidinones. This randomized, double-blind, placebo-controlled, 2-period,
Shawn Flanagan, Philippe Prokocimer, Sonia Minassian   +2 more
core   +1 more source

Tedizolid-Cyclodextrin System as Delayed-Release Drug Delivery with Antibacterial Activity

, 2020
Progressive increase in bacterial resistance has caused an urgent need to introduce new antibiotics, one of them being oxazolidinones with their representative tedizolid. Despite the broad spectrum of activity of the parent tedizolid, it is characterized
Judyta Cielecka-Piontek, Katarzyna Michalska, Anita Płazińska, Ewa Tykarska, Daria Szymanowska, Magdalena Paczkowska-Walendowska, Natalia Rosiak, Wojciech Płaziński   +7 more
core   +1 more source

Genetic Characterization of a Linezolid‐ and Penicillin‐Resistant Enterococcus hirae Isolate Co‐Harboring poxtA and pbp5fm

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Linezolid and penicillin are critical for treating multidrug resistant (MDR) Gram‐positive infections, but the emergence of resistance to both seriously threatens public health. Here, we first report the cocarrying poxtA (oxazolidinone resistance) and pbp5fm (β‐lactam resistance) genes by the plasmid in a strain of Enterococcus hirae HDC14‐2 derived ...
Jinhu Huang, Aijuan Li, Mengli Wang, Shushu Gu, He Hu, Xiaoming Wang, Liping Wang, Zhong Peng   +7 more
wiley   +1 more source