Results 11 to 20 of about 1,717 (156)

Tedizolid Phosphate [PDF]

open access: yesHospital Pharmacy, 2014
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing
Dennis J, Cada   +2 more
openaire   +2 more sources

Poor removal of tedizolid during continuous hemodiafiltration: experiments using an in vitro continuous hemodiafiltration model

open access: yesJournal of Pharmaceutical Health Care and Sciences, 2023
Background Tedizolid is an oxazolidinone anti-MRSA drug with included in the National Health Insurance Drug Price List in 2018. The effect of hemodialysis on tedizolid phosphate concentrations has been reported; pre-dialysis concentrations decreased by ...
Satoshi Yoshikawa   +3 more
doaj   +1 more source

Safety and tolerability of tedizolid as oral treatment for bone and joint infections

open access: yesMicrobiology Spectrum, 2023
Bone and joint infections (BJIs) are common infections increasingly managed with oral therapy. However, there are limited safe oral options for many Gram-positive pathogens.
Loren G. Miller   +10 more
doaj   +1 more source

Pharmacokinetic/Pharmacodynamic Analysis of Tedizolid Phosphate Compared to Linezolid for the Treatment of Infections Caused by Gram-Positive Bacteria

open access: yesAntibiotics, 2021
Tedizolid and linezolid have antibacterial activity against the most important acute bacterial skin and skin-structure infection (ABSSSIs) pathogens.
Alicia Rodríguez-Gascón   +3 more
doaj   +1 more source

Comparative study of in vitro activity of tedizolid and linezolid against Mycobacterium avium complex.

open access: yesJournal of Global Antimicrobial Resistance, 2022
Objectives: The aim of this study is to compare the in vitro activity and minimal inhibitory concentration (MIC) distributions of tedizolid and linezolid against Mycobacterium avium complex (MAC) strains using a reference broth microdilution assay and a ...
Eduardo Marfil   +3 more
doaj   +1 more source

Tedizolid: new data and experiences for clinical practice [PDF]

open access: yesRevista Española de Quimioterapia, 2021
The most relevant information on the clinical uses of tedizolid from studies published in the last 18 months is presented in this brief review. The most important data indicate better tolerance and safety profile of long-term therapeutic regimes in off-label indications, such as osteoarticular infections and those caused by mycobacteria. Its lower risk
Salavert Lleti, M   +3 more
openaire   +3 more sources

Efficacy, safety, tolerability and population pharmacokinetics of tedizolid, a novel antibiotic, in Latino patients with acute bacterial skin and skin structure infections

open access: yesBrazilian Journal of Infectious Diseases, 2016
Acute bacterial skin and skin structure infections are caused mainly by Gram-positive bacteria which are often treated with intravenous vancomycin, daptomycin, or linezolid, with potential step down to oral linezolid for outpatients.
Alejandro Ortiz-Covarrubias   +9 more
doaj   +1 more source

Tedizolid activity against a multicentre worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae recovered from patients with pneumonia (2017–2019)

open access: yesInternational Journal of Infectious Diseases, 2021
Objectives: The antimicrobial activity of tedizolid and comparators was evaluated against a large worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae isolates recovered from patients with pneumonia.
Cecilia G. Carvalhaes   +3 more
doaj   +1 more source

Thrombocytopenia with Tedizolid and Linezolid [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2018
ABSTRACT Several studies have suggested the risk of thrombocytopenia with tedizolid, a second-in-class oxazolidinone antibiotic (approved June 2014), is less than that observed with linezolid (first-in-class oxazolidinone). Using data from the Food and Drug Administration adverse event reporting system (July 2014 through December 2016), we ...
Lee, Erica Yookyung, Caffrey, R
openaire   +3 more sources

Tedizolid Phosphate: a Next-Generation Oxazolidinone [PDF]

open access: yesInfectious Diseases and Therapy, 2015
Treatment of multidrug-resistant Gram-positive infections continues to challenge clinicians as the emergence of new resistance mechanisms outpaces introduction of novel antimicrobial agents. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus
Rybak, Jeffrey M., Roberts, Karrine
openaire   +2 more sources

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