Results 171 to 180 of about 161,718 (344)
924. Enhanced Tumor Cell Specificity and Efficacy of Conditional Replication Competent Adenovirus Controlled by Modified Human Telomerase Promoter (m-hTERT) [PDF]
, 2003 openalex +1 more source
Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration
Journal of Periodontal Research, EarlyView.The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa +5 more
wiley +1 more source
Journal of Periodontal Research, EarlyView.A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Telomerase activity: An attractive target for cancer therapeutics
, 2014 Lucia Picariello
openalex +1 more source
Circulating Cell‐Free DNA Concentration as a Biomarker in Head and Neck Cancer
Oral Diseases, EarlyView.ABSTRACT Objective Head and neck squamous cell carcinoma (HNSCC), particularly human papillomavirus (HPV) ‐negative HNSCC, poses a significant clinical challenge due to late diagnoses and poor survival. This study evaluates the potential of circulating cell‐free DNA (ccfDNA) as a minimally invasive biomarker for diagnosis, prognosis and disease ...
Ana María Rodríguez‐Ces +7 more
wiley +1 more source
Telomere, telomerase and telomerase inhibitors
Bioorganic and Medicinal Chemistry Reports, 2020 Rahime Simsek, Yusuf Ataker
openaire +1 more source
RPA regulates telomerase action by providing Est1p access to chromosome ends [PDF]
, 2003 Véra Schramke +7 more
openalex +1 more source
The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes
Molecular Oral Microbiology, EarlyView.ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes +6 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye +5 more
wiley +1 more source