Results 181 to 190 of about 47,830 (278)

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, Volume 13, Issue 39, 13 July 2026.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source

The adaptive molecular landscape of reprogrammed telomeric sequences. [PDF]

Nat Commun
D'Angiolo M, Barré BP, Khaiwal S, Muenzner J, Hallin J, De Chiara M, Tellini N, Warringer J, Ralser M, Gilson E, Liti G.   +10 more
europepmc   +1 more source

Nuclear dysfunction in aging and neurodegeneration

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Neurodegenerative diseases are characterized by a loss of neuronal function and structure, often in a region‐specific manner. Multiple factors contribute to neuronal dysfunction and death, including pathogenic protein buildup, protein mislocalization, and inflammation. Despite extensive research, the common mechanisms driving neurodegeneration
Abbigael Aday, Jack Tiller, Adarsh Melukote, Zachary C. Walton, Anna King, Luke Castillo, Rakez Kayed, Mauro Montalbano   +7 more
wiley   +1 more source

Epitranscriptomic control of telomere maintenance. [PDF]

Mol Biol Rep
Ahi EP, Ghasemishahrestani Z.
europepmc   +1 more source

Titin Is Present in the Elastic Tethers That Connect Separating Anaphase Chromosomes in Crane‐Fly Spermatocytes

Cytoskeleton, Volume 83, Issue 7, Page 496-514, July 2026.
ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos, Maral Janan, Martina Krüger, Aavo‐Valdur Mikelsaar, Arthur Forer, Rose Sheykhani   +5 more
wiley   +1 more source

Correction: Telomeric Repeats Facilitate CENP-A Incorporation via Telomere Binding Proteins.

PLoS ONE, 2013
Araceli G. Castillo, Alison L. Pidoux, Sandra Catania, Mickaël Durand-Dubief, Eun Shik Choi, Georgina Hamilton, Karl Ekwall, Robin C. Allshire   +7 more
doaj   +1 more source

Transcriptional regulation in cardiovascular aging. [PDF]

Front Cardiovasc Med
Fan Y, Song C, Feng F, Xun Q, Lu Y, Li C.   +5 more
europepmc   +1 more source

Acrylamide Exposure, Biological Aging Acceleration, With Ankle‐Brachial Index and Peripheral Artery Disease: Exploring Association, Interaction, and Underlying Mechanism

Food Frontiers, Volume 7, Issue 4, July 2026.
We provided the first evidence that exposure of general adults to ACR was related to ABI decrement and PAD odds increment, which might be partly associated with accelerated biological aging. Lipid and atherosclerosis pathway may be suggestively implicated in the mechanism underlying these associations.
Feifei Wang, Zhiying Huo, Jiahao Song, Shuhui Wan, Yongfang Zhang, Le Hong, Qing Liu, Yani Xiong, Pengfei Chen, Yanjun Guo, Weihong Chen, Bin Wang   +11 more
wiley   +1 more source

Telomere Length in Metabolic Syndrome: Mechanisms, Epidemiology and Clinical Implications: A Narrative Review. [PDF]

Diabetes Metab Syndr Obes
Cilia K, Gauci Z, Agius R, Fava S, Pace NP.   +4 more
europepmc   +1 more source

In Vitro Antineoplastic Effects of Zataria multiflora: A Systematic Review of Mechanisms, Selectivity, and Synergy

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Zataria multiflora (ZM) is an aromatic plant containing various bioactive components, including phenolic compounds, flavonoids, and terpenoids. Here, we systematically review 27 articles to explore the effect of ZM on different cancer/normal cell lines.
Alireza Khanahmad, Fatemeh Peymaninezhad, Fariba Sharififar, Ali Sadatmoosavi, Ali Bazi, Roohollah Mirzaee Khalilabadi, Hajar Mardani Valandani   +6 more
wiley   +1 more source