Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Telomere-to-telomere assemblies of chromosome 10 reveal complex adaptive variation of 3-ketoacyl-CoA-synthases in <i>Populus trichocarpa</i> likely driven by Helitrons. [PDF]
Kainer D +21 more
europepmc +1 more source
Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley +1 more source
Multicellular senescence programs in the aged heart. [PDF]
Bultot L +3 more
europepmc +1 more source
The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer
ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli +1 more
wiley +1 more source
Practitioner Review: Infant mental health meets cell and molecular biology – a look to the future
Background A major research effort in the past two decades has begun to illuminate how experience ‘gets under the skin’ – that is – the cellular and molecular processes that are associated with adversity and resilience. Methods We selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory
Charles H. Zeanah +3 more
wiley +1 more source
MicroRNA-Mediated Regulation of Brain Aging Hallmarks: Implications for Neurodegeneration and Neural Recovery. [PDF]
Ardah MT +7 more
europepmc +1 more source
Pan‐genome analysis reveals that high‐altitude Rhododendron species resist alpine cold stress by rapidly sensing and engaging the chilling response pathway and genes that directly and indirectly protect the plant from UV radiation. Heritable genomic features such as long terminal repeats contribute to the adaptive diversification of Rhododendron ...
Haoyang Zhou +11 more
wiley +1 more source
ABSTRACT Background Cutaneous aging is characterized by progressive degradation of the extracellular matrix, manifesting as diminished hydration, loss of elasticity, and increased wrinkle depth. While oral hydrolyzed collagen peptides (HCPs) are increasingly utilized as systemic nutricosmetics, previous evidence syntheses have been limited by severe ...
Asia Batool +11 more
wiley +1 more source
G-quadruplex stabilization via small molecules as a potential anti-cancer strategy. [PDF]
Li C, Liu J, Wang R.
europepmc +1 more source

