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Telomere-binding proteins of Arabidopsis thaliana
Plant Molecular Biology, 1995The nucleoprotein structure of Arabidopsis thaliana telomeres was investigated. A protein specifically binding to telomeric sequences was characterized by gel mobility shift assays with synthetic oligonucleotides consisting of four 7 bp telomeric repeats of Arabidopsis (TTTAGGG) and crude nuclear protein extracts of Arabidopsis leaves.
Ulrike Zentgraf +2 more
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Chaperone Association with Telomere Binding Proteins [PDF]
, 2009 VCU Theses and ...
Depcrynski, Amy
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Telomere-Binding Proteins in Humans [PDF]
, 2009 Shelterin, the telomere-secific protein complex, is essential for genome stability and cell viability. Shelterin accumulates at telomeres and transforms chromosome ends into specialized structures that evade recognition by the DNA damage signaling and repair machineries and are maintained through consecutive cell divisions. Shelterin accomplishes these
Nadya Dimitrova
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Journal of Pediatric Surgery, 2009
Neuroblastoma (NBL) shows remarkable biologic heterogeneity, resulting in favorable or unfavorable prognoses. Previously, we reported that most unfavorable NBLs express high telomerase activity to maintain telomere length. Recently, telomere binding proteins (TBPs) and alternative lengthening of telomeres (ALTs) have been identified as key factors of ...
Yoshiyuki Onitake +2 more
exaly +3 more sources
Neuroblastoma (NBL) shows remarkable biologic heterogeneity, resulting in favorable or unfavorable prognoses. Previously, we reported that most unfavorable NBLs express high telomerase activity to maintain telomere length. Recently, telomere binding proteins (TBPs) and alternative lengthening of telomeres (ALTs) have been identified as key factors of ...
Yoshiyuki Onitake +2 more
exaly +3 more sources
Using the Telobox to Search for Plant Telomere Binding Proteins [PDF]
Current Protein & Peptide Science, 2011 Telobox is a Myb-related DNA-binding domain which is present in a number of yeast, plant and animal proteins. Its capacity to bind preferentially double-stranded telomeric DNA has been used in numerous studies to search for candidate telomeric proteins in various organisms, including plants.
Vratislav, Peška +2 more
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Telomere-Binding Proteins of Ciliated Protozoa [PDF]
, 1995 A great deal of our current knowledge about telomere structure and function has come from studies performed with ciliated protozoa. The reason that studies of ciliate telomeres have been so productive stems from the unusual genomic organization of these organisms.
C. M. Price
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Telomere-binding Proteins in Fission Yeast [PDF]
, 2006 The telomere is a specialized heterochromatin localized at the end of the linear chromosome, and is essential for the multiple aspects of genome integrity. Telomere functions are performed mostly by telomere-binding proteins. Although many of the telomere-binding proteins are conserved among species, some variations exist. Recent studies of the fission
Junko Kanoh
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Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins
Nature Reviews Cancer, 2011Mammalian telomeres are formed by tandem repeats of the TTAGGG sequence, which are progressively lost with each round of cell division. Telomere protection requires a minimal length of TTAGGG repeats to allow the binding of shelterin, which prevents the activation of a DNA damage response (DDR) at chromosome ends.
Paula Martinez +2 more
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