Results 21 to 30 of about 130,635 (210)

Analysis of telomere maintenance in artemis defective human cell lines [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Telomeres are physical ends of chromosomes consisting of (TTAGGG)n DNA sequence and a specialized set of proteins that protect chromosomal ends from ...
Yasaei, Hemad
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Is telomere length a biomarker for aging: cross-sectional evidence from the west of Scotland? [PDF]

, 2012
Background <p> The search for biomarkers of aging (BoAs) has been largely unsuccessful to-date and there is widespread skepticism about the prospects of finding any that satisfy the criteria developed by the American Federation of Aging Research ...
Batty, G.D., Robertson, T., Shiels, PG, Shiels Paul G., Benzeval, Michaela, Michaela Benzeval, McGlynn, Liane, G David Batty, Ian J Deary, McIntyre, A., McIntyre, A, Michael J Green, Benzeval, M, Tony Robertson, Der, G, Alan McIntyre, Paul G Shiels, McIntyre Alan, Robertson, Tony, Shiels, Paul G, Green, Michael J, Green, M.J., McGlynn Liane, McIntyre, Alan, Deary, Ian J, Der, Geoff, Robertson, T, Geoff Der, Green, MJ, McGlynn, L., McGlynn, L, Green Michael J., Deary, Ian, Deary Ian J., Der, G., Liane McGlynn, Batty G. David, McGlynn, Liane M, Robertson Tony, Batty, GD, Benzeval, M., Shiels, P.G., Batty, G David, Benzeval Michaela, Deary, IJ, Deary, I.J., Der Geoff   +46 more
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Telomere Length and Physical Performance at Older Ages: An Individual Participant Meta-Analysis [PDF]

, 2013
Background Telomeres are involved in cellular ageing and shorten with increasing age. If telomere length is a valuable biomarker of ageing, then telomere shortening should be associated with worse physical performance, an ageing trait, but evidence ...
Hardy, R, John M. Starr (107707), Cooper, R, Rachel Cooper, von Zglinicki, Thomas, Halcyon study team, Parsons, Sam, Martin-Ruiz, C., Lennox, Alison, Kuh, D., Murray, Emily, Yoav Ben-Shlomo, Aihie Sayer, Avan, Shiels, Paul G, Thomas von Zglinicki, Martin, Richard, Carmen Martin-Ruiz (126509), Cooper Cyrus, Hardy, R., Hardy, Rachel, Deary, Ian, Gardner, M.P., Team, HS, Cooper, Cryus, von Zglinicki, T., Sayer Avan Aihie, John M Starr, Shiels, P.G., Ben-Shlomo, Yoav, Ian J. Deary (107724), Harris, Sarah E, Gardner, Michael, Sayer, AA, Day, Ian, team, Halcyon study, Sarah E Harris, Ian J Deary, Gallacher, J., Aucott, Paula, Harris, Sarah, Martin-Ruiz, C, Paul G Shiels, Gardner, MP, Southall, Humphrey, Kuh, Diana, Rebecca Hardy (188906), von Zglinicki Thomas, Deary, Ian J, Michael P. Gardner (381155), Goodwin, James, Michael P Gardner, Thomas von Zglinicki (73277), Yoav Ben-Shlomo (95286), Alfred, Tamuno, Cooper, C., Diana Kuh, Gallacher John, Ben-Shlomo, Y., Starr John M., Deary Ian J., Elliott, Jane, Cooper, C, Starr, J.M., Shiels, Paul G., Shiels, Paul, Rachel Cooper (188902), Shiels, PG, Harris Sarah E., Kuh Diana, Gallacher, John, Gardner, Michael P., Craig, Leone, Richards, Marcus, Starr, John M., John Gallacher, Mulla, Zeinab, Starr, John M, Gale, Catherine, Ben-Shlomo, Y, Carmen Martin-Ruiz, Demakakos, Panos, Gardner, Mike P, Cyrus Cooper (141250), Cooper, R., John Gallacher (196569), Sayer, A.A., Cyrus Cooper, Harris, S.E., Hardy, Rebecca, McNeill, Geraldine, Starr, JM, Harris, SE, ?, ?, Avan Aihie Sayer, Cooper, Rachel, Deary, IJ, Cooper Rachel, Gardner, Michael P, Avan Aihie Sayer (188916), Rebecca Hardy, Whalley, Lawrence, Shiels Paul G., Martin-Ruiz Carmen, Hardy Rebecca, Martin-Ruiz, Carmen, Deary, Ian J., Tilling, Kate, Harris, Sarah E., Gardner Michael P., Cooper, Cyrus, Power, Chris, Paul G. Shiels (125083), Sayer, Avan Aihie, Gallacher, J, Mishra, Gita, von Zglinicki, T, Kuh, D, von, Zglinicki T, Steptoe, Andrew, Ben-Shlomo Yoav, Sarah E. Harris (107676), Diana Kuh (188923), Starr, John, Deary, I.J.   +123 more
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Circulating leukocyte telomere length is highly heritable among families of Arab descent [PDF]

, 2012
Background Telomere length, an indicator of ageing and longevity, has been correlated with several biomarkers of cardiometabolic disease in both Arab children and adults.
Alokail Majed S, Shaun B Sabico, Assim A Alfadda, Sabico, Shaun, George P Chrousos, Omar S Al-Attas, Alokail, Majed S., Al-Attas, Omar S., Philip McTernan, Al-Daghri, Nasser M., Greg C Gibson, Al-Attas Omar S, Majed S Alokail, Gibson, Greg, Alkharfy Khalid M, Alfadda, Assim, Chrousos, George P., Gibson Greg C, Chrousos George P, McTernan Philip, Nasser M Al-Daghri, Sabico Shaun B, Al-Daghri Nasser M, Alfadda Assim A, Alkharfy, Khalid M., McTernan, P. G. (Philip G.), Khalid M Alkharfy   +26 more
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Change in Leukocyte Telomere Length Predicts Mortality in Patients with Stable Coronary Heart Disease from the Heart and Soul Study. [PDF]

PLoS ONE, 2016
Short telomere length independently predicts mortality in patients with coronary heart disease. Whether 5-year change in telomere length predicts subsequent mortality in patients with coronary heart disease has not been evaluated.In a prospective cohort ...
Sarah E Goglin, Ramin Farzaneh-Far, Elissa S Epel, Jue Lin, Elizabeth H Blackburn, Mary A Whooley   +5 more
doaj   +1 more source

Telomere-to-telomere analysis of CA14/NRRL 3357 AT indels in A. flavus chromosomes.

, 2023
Telomere-to-telomere analysis of CA14/NRRL 3357 AT indels in A. flavus chromosomes.
Arthur J. Lustig (14593621)
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Sir4 Deficiency Reverses Cell Senescence by Sub-Telomere Recombination

Cells, 2021
Telomere shortening results in cellular senescence and the regulatory mechanisms remain unclear. Here, we report that the sub-telomere regions facilitate telomere lengthening by homologous recombination, thereby attenuating senescence in yeast ...
Jun Liu, Xiaojing Hong, Lihui Wang, Chao-Ya Liang, Jun-Ping Liu   +4 more
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Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition [PDF]

, 2013
© 2013 Yasaei et al.; licensee BioMed Central Ltd.This article has been made available through the Brunel Open Access Publishing Fund.Telomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity.
Slijepcevic, P, Yaghoub Gozaly-Chianea, Yasaei, H, Predrag Slijepcevic, Hemad Yasaei, Gozaly-Chianea, Y   +5 more
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Telomeres in Fishes [PDF]

Cytogenetic and Genome Research, 2013
In fishes, as in other vertebrate species, the DNA component of the telomeres consists of the tandemly repeated TTAGGG motif. The length of the telomeric arrays in fishes ranges from 2 to 25 kb and shortens with age in some of the species. To date, chromosomal distribution of the telomeric DNA sequences has been examined in approximately 80 fish ...
openaire   +2 more sources

Trf1 is not required for proliferation or functional telomere maintenance in chicken DT40 cells [PDF]

, 2009
© 2009 by The American Society for Cell Biology.The telomere end-protection complex prevents the ends of linear eukaryotic chromosomes from degradation or inappropriate DNA repair. The homodimeric double-stranded DNA-binding protein, Trf1, is a component
Modino, S, Cooley, C, Cooley, C., Farr, CJ, Farr, C. J., Slijepcevic, P., Baird, K. M., Stewart, J. L., Slijepcevic, P, Baird, KM, Wenner, T., Stewart, JL, Faure, V., Morrison, C. G., Morrison, CG, Wenner, T, Modino, S., Faure, V, Stewart, Jillian, Faure, Virginie, Cooley, Carol, Morrison, Ciaran, Slijepcevic, Predrag, Wenner, Thomas, Farr, Christine, Modino, Sonie, Baird, Katie   +26 more
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