Telomeres susceptibility to environmental arsenic exposure: Shortening or lengthening?
Frontiers in Public Health, 2023 Maintaining telomere length plays a crucial role in regulating cellular life span. Telomere lengthening or shortening is one of the important biomarkers which could predict the preceding or present diseases. Meanwhile, the impact of environmental arsenic
Kyi Mar Wai +5 more
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Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR. [PDF]
, 2011 Telomere length/DNA content has been measured in epidemiological/clinical settings with the goal of testing a host of hypotheses related to the biology of human aging, but often the conclusions of these studies have been inconsistent.
Aviv, Abraham +5 more
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Biological embedding of maternal postpartum depressive symptoms: The potential role of cortisol and telomere length. [PDF]
, 2020 Although maternal postpartum depressive symptoms (PDS) are associated with child behavior problems, the underlying biological mechanisms are poorly understood.
Beijers, Roseriet +4 more
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Senescence, Telomere Shortening and Telomere Maintenance [PDF]
Cancer Biology & Therapy, 2002 No Abstract Available Commentary to: Title: Telomerase Protects Cancer-Prone Human Cells from Chromosomal Instability and Spontaneous Immortalization Authors: Lynne W. Elmore, Kristi C. Turner, Lauren S. Gollahon, Melissa R. Landon, Colleen K. Jackson-Cook and Shawn E.
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Telomere length comparison between oral cells and blood cells among neonates
The Turkish Journal of Pediatrics, 2019 Telomere length, measured from blood cells, is commonly used as the standard telomere length of the whole body. The relationship between blood telomere length and oral telomere length is still unclear, especially among neonates.
Mandar Bhattacharya +2 more
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p53 mediates failure of human definitive hematopoiesis in dyskeratosis congenita [PDF]
, 2017 Summary: Dyskeratosis congenita (DC) is a bone marrow failure syndrome associated with telomere dysfunction. The progression and molecular determinants of hematopoietic failure in DC remain poorly understood.
Batista, Luis Francisco Zirnberger +5 more
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Identification of Neuroblastoma Subgroups Based on Three-Dimensional Telomere Organization
Translational Oncology, 2016 Using 3D telomere quantitative fluorescence in situ hybridization, we determined the 3D telomere organization of 74 neuroblastoma tissue samples. Hierarchical cluster analysis of the measured telomere parameters identified three subgroups from our ...
Alexandra Kuzyk +2 more
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Telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans [PDF]
, 2018 Sulfur Mustard (SM) is the most widely used chemical weapon. It was used in World War 1 and in the more recent Iran-Iraq conflict. Genetic toxicity and DNA alkylation effects of SM in molecular and animal experiments are well documented.
Ahmadimanesh, Mahnaz +8 more
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Telomere tracking from birth to adulthood and residential traffic exposure
BMC Medicine, 2017 Background Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length.
Esmée M. Bijnens +9 more
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Association between exposure to second-hand smoke and telomere length: cross-sectional study of 1303 non-smokers [PDF]
, 2017 Background: Both active smoking and second-hand smoke (SHS) are important risk factors for many age-related diseases. Active smoking is associated with shortened telomere length. However, whether SHS accelerates telomere attrition with age is uncertain.
Johnman, Cathy +5 more
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