Results 31 to 40 of about 130,635 (210)
Measuring telomere length and telomere dynamics in evolutionary biology and ecology [PDF]
, 2014 Telomeres play a fundamental role in the protection of chromosomal DNA and in the regulation of cellular senescence. Recent work in human epidemiology and evolutionary ecology suggests adult telomere length (TL) may reflect past physiological stress and ...
Barrett, Emma +17 more
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Telomere-to-telomere (T2T) genome of the model plant Physcomitrium patens
, 2023 An exemplary assembly of the P. patens nuclear genome, which incorporates telomeres and centromere regions, thereby establishing it as the first telomere-to-telomere (T2T) genome in a nonseed plant.
Shijun Zhao (15687284)
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Genes, 2022 Telomeres are essential structures formed from satellite DNA repeats at the ends of chromosomes in most eukaryotes. Satellite DNA repeat sequences are useful markers for karyotyping, but have a more enigmatic role in the eukaryotic cell. Much work has been done to investigate the structure and arrangement of repetitive DNA elements in classical models ...
Leon P. Jenner +3 more
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Telomere-to-telomere genome assembly of the Taihu goose
, 2023 Our study presents the pioneering assembly of a high-quality Taihu goose genome at the Telomere-to-Telomere (T2T) level. By employing advanced sequencing technologies, including Pacific Biosciences HiFi reads, Oxford Nanopore long reads, Illumina short ...
Hongchang Zhao (17625645)
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Telomere length comparison between oral cells and blood cells among neonates
The Turkish Journal of Pediatrics, 2019 Telomere length, measured from blood cells, is commonly used as the standard telomere length of the whole body. The relationship between blood telomere length and oral telomere length is still unclear, especially among neonates.
Mandar Bhattacharya +2 more
doaj +1 more source
The JIL-1 kinase affects telomere expression in the different telomere domains of Drosophila. [PDF]
PLoS ONE, 2013 In Drosophila, the non-LTR retrotransposons HeT-A, TART and TAHRE build a head-to-tail array of repetitions that constitute the telomere domain by targeted transposition at the end of the chromosome whenever needed. As a consequence, Drosophila telomeres
Rute Silva-Sousa, Elena Casacuberta
doaj +1 more source
Telomeres susceptibility to environmental arsenic exposure: Shortening or lengthening?
Frontiers in Public Health, 2023 Maintaining telomere length plays a crucial role in regulating cellular life span. Telomere lengthening or shortening is one of the important biomarkers which could predict the preceding or present diseases. Meanwhile, the impact of environmental arsenic
Kyi Mar Wai +5 more
doaj +1 more source
Telomeric recombination induced by dysfunctional telomeres
Molecular Biology of the Cell, 2011 Telomere maintenance is essential for cellular immortality, and most cancer cells maintain their telomeres through the enzyme telomerase. Telomeres and telomerase represent promising anticancer targets. However, 15% of cancer cells maintain their telomeres through alternative recombination-based mechanisms, and previous analyses showed that ...
Brault, Marie Eve, Autexier, Chantal
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Association of telomere instability with senescence of porcine cells
BMC Cell Biology, 2012 Background Telomeres are essential for the maintenance of genomic stability, and telomere dysfunction leads to cellular senescence, carcinogenesis, aging, and age-related diseases in humans. Pigs have become increasingly important large animal models for
Ji Guangzhen +4 more
doaj +1 more source
Telomeres and telomerase [PDF]
Genes & Development, 1999 Telomeres are in the spotlight of modern biology. Whether the subject at hand is cancer, gene regulation, organismal aging, or the cloning of mammals, much seems to depend on what happens at the ends of chromosomes. Because glamorous hypotheses often persist without experimental support, it is important to ask ourselves what we really know about ...
Blasco, M. A. +2 more
openaire +2 more sources