Results 31 to 40 of about 128,303 (302)

Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort [PDF]

, 2011
BACKGROUND: It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease.
Batty, G.D., McGlynn, LM, Jennifer S McLean, Johnson, P.C.D., MacIntyre, Alan, Ford Ian, Yoga Nathan (12346540), Tannahill, Carol, Carol Tannahill, McLean, JS, McGinty, A., Liane M. McGlynn (12597766), Millar, K, MacIntyre, A., McConnachie, A, Burns Harry, MacIntyre Alan, Cavanagh Jonathan, Cavanagh, Jonathan, Tannahill Carol, Shiels, P.G., Chris J. Packard, Jonathan Cavanagh (125077), Deans, K.A., Kevin A. Deans, McGinty Agnes, Chris J. Packard (12592780), Tannahill, C., Keith Millar, Jennifer S. Mclean, Ford, I, Sattar, N., G David Batty, Kevin A. Deans (12592774), McGlynn Liane M., Burns, Harry, Ford, I., Paul G Shiels, Sattar Naveed, Naveed Sattar (8785), Batty, David G., Harry Burns (125075), McConnachie Alex, Liane M. Mcglynn, Packard, C.J., Burns, H, McGinty, Agnes, Miller, Keith, Cavanagh, J., Johnson, Paul C.D., McLean, Jennifer S., Sattar, Naveed, Packard, CJ, Batty G. David, Batty, GD, Johnson, PCD, Shiels, Paul G., Shiels, PG, Paul C. D. Johnson, G. David Batty, Paul C D Johnson, McLean Jennifer S., Sattar, N, Chris J Packard, Burns, H., Millar, K., McGinty, A, Ian Ford, Alex McConnachie (104022), Agnes McGinty, Deans Kevin A., Velupillai, YN, Jennifer S. McLean (12592768), McConnachie, A., Ian Ford (30666), MacIntyre, A, Millar Keith, Velupillai Yoga N., Paul C.D. Johnson (12597769), McConnachie, Alex, Deans, KA, McGlynn, L.M., Naveed Sattar, Paul G. Shiels (12592783), Ford, Ian, Liane M McGlynn, Shiels Paul G., Agnes McGinty (212297), Keith Miller (2363098), Kevin A Deans, Paul G. Shiels, Jonathan Cavanagh, Carol Tannahill (212305), Chris J, McGlynn, Liane M., Deans, Kevin A., Alex McConnachie, David G. Batty (12592771), Cavanagh, J, Velupillai, Y.N., Alan MacIntyre, Johnson Paul C. D., Nathan, Yoga, Alan MacIntyre (212284), McLean, J.S., Tannahill, C, Yoga N Velupillai, Harry Burns, Packard Chris J., Packard, Chris J., Yoga N. Velupillai   +110 more
core   +1 more source

Telomeres and Their Neighbors

Genes, 2022
Telomeres are essential structures formed from satellite DNA repeats at the ends of chromosomes in most eukaryotes. Satellite DNA repeat sequences are useful markers for karyotyping, but have a more enigmatic role in the eukaryotic cell. Much work has been done to investigate the structure and arrangement of repetitive DNA elements in classical models ...
Leon P. Jenner, Vratislav Peska, Jana Fulnečková, Eva Sýkorová   +3 more
openaire   +2 more sources

Telomere length comparison between oral cells and blood cells among neonates

The Turkish Journal of Pediatrics, 2019
Telomere length, measured from blood cells, is commonly used as the standard telomere length of the whole body. The relationship between blood telomere length and oral telomere length is still unclear, especially among neonates.
Mandar Bhattacharya, Pranami Bhaumik, Subrata Kumar-Dey   +2 more
doaj   +1 more source

The JIL-1 kinase affects telomere expression in the different telomere domains of Drosophila. [PDF]

PLoS ONE, 2013
In Drosophila, the non-LTR retrotransposons HeT-A, TART and TAHRE build a head-to-tail array of repetitions that constitute the telomere domain by targeted transposition at the end of the chromosome whenever needed. As a consequence, Drosophila telomeres
Rute Silva-Sousa, Elena Casacuberta
doaj   +1 more source

Telomeres susceptibility to environmental arsenic exposure: Shortening or lengthening?

Frontiers in Public Health, 2023
Maintaining telomere length plays a crucial role in regulating cellular life span. Telomere lengthening or shortening is one of the important biomarkers which could predict the preceding or present diseases. Meanwhile, the impact of environmental arsenic
Kyi Mar Wai, Kyi Mar Wai, Thinzar Swe, Maw Thoe Myar, Cindy Rahman Aisyah, Thae Su Su Hninn   +5 more
doaj   +1 more source

Telomeric recombination induced by dysfunctional telomeres

Molecular Biology of the Cell, 2011
 Telomere maintenance is essential for cellular immortality, and most cancer cells maintain their telomeres through the enzyme telomerase. Telomeres and telomerase represent promising anticancer targets. However, 15% of cancer cells maintain their telomeres through alternative recombination-based mechanisms, and previous analyses showed that ...
Brault, Marie Eve, Autexier, Chantal
openaire   +2 more sources

Telomeres and telomerase [PDF]

Genes & Development, 1999
Telomeres are in the spotlight of modern biology. Whether the subject at hand is cancer, gene regulation, organismal aging, or the cloning of mammals, much seems to depend on what happens at the ends of chromosomes. Because glamorous hypotheses often persist without experimental support, it is important to ask ourselves what we really know about ...
Blasco, M. A., Gasser, S. M., Lingner, J.   +2 more
openaire   +2 more sources

Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition [PDF]

, 2013
© 2013 Yasaei et al.; licensee BioMed Central Ltd.This article has been made available through the Brunel Open Access Publishing Fund.Telomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity.
Slijepcevic, P, Yaghoub Gozaly-Chianea, Yasaei, H, Predrag Slijepcevic, Hemad Yasaei, Gozaly-Chianea, Y   +5 more
core   +1 more source

Association of telomere instability with senescence of porcine cells

BMC Cell Biology, 2012
Background Telomeres are essential for the maintenance of genomic stability, and telomere dysfunction leads to cellular senescence, carcinogenesis, aging, and age-related diseases in humans. Pigs have become increasingly important large animal models for
Ji Guangzhen, Liu Kai, Okuka Maja, Liu Na, Liu Lin   +4 more
doaj   +1 more source

Identification of Neuroblastoma Subgroups Based on Three-Dimensional Telomere Organization

Translational Oncology, 2016
Using 3D telomere quantitative fluorescence in situ hybridization, we determined the 3D telomere organization of 74 neuroblastoma tissue samples. Hierarchical cluster analysis of the measured telomere parameters identified three subgroups from our ...
Alexandra Kuzyk, John Gartner, Sabine Mai   +2 more
doaj   +1 more source