Results 41 to 50 of about 110,609 (302)
Stress exposure in early post-natal life reduces telomere length: an experimental demonstration in a long-lived seabird [PDF]
, 2014 Exposure to stressors early in life is associated with faster ageing and reduced longevity. One important mechanism that could underlie these late life effects is increased telomere loss. Telomere length in early post-natal life is an important predictor
Adam, Aileen +6 more
core +4 more sources
Telomere tracking from birth to adulthood and residential traffic exposure
BMC Medicine, 2017 Background Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length.
Esmée M. Bijnens +9 more
doaj +1 more source
Postępy Higieny i Medycyny Doświadczalnej, 2013 Telomeres protect the ends of chromosomes maintaining genome stability. The activity of telomerase enzyme, or alternatively the process of recombination, regulates the length of telomeres. In the absence of these mechanisms, excessive shortening of telomeres reach its critical level.
openaire +2 more sources
iScienceSummary: Alternative lengthening of telomeres (ALT) is a homology-directed repair mechanism that becomes activated in a subset of cancers to maintain telomere length.
Robert Lu +5 more
doaj +1 more source
Telomere shortening unrelated to smoking, body weight, physical activity, and alcohol intake: 4,576 general population individuals with repeat measurements 10 years apart. [PDF]
PLoS Genetics, 2014 Cross-sectional studies have associated short telomere length with smoking, body weight, physical activity, and possibly alcohol intake; however, whether these associations are due to confounding is unknown.
Maren Weischer +2 more
doaj +1 more source
Does oxidative stress shorten telomeres in vivo? A review [PDF]
, 2017 The length of telomeres, the protective caps of chromosomes, is increasingly used as a biomarker of individual health state because it has been shown to predict chances of survival in a range of endothermic species including humans.
Reichert, Sophie, Stier, Antoine
core +1 more source
Telomere Length in Elite Athletes
International Journal of Sports Physiology and Performance, 2017 Growing evidence suggests that regular moderate-intensity physical activity is associated with an attenuation of leukocyte telomere length (LTL) shortening. However, more controversy exists regarding higher exercise loads such as those imposed by elite-sport participation.Methods:The authors investigated LTL differences between young elite athletes (n =
Muniesa Ferrero, Carlos Alberto +9 more
openaire +4 more sources
Early-Life Telomere Dynamics Differ between the Sexes and Predict Growth in the Barn Swallow (Hirundo rustica). [PDF]
PLoS ONE, 2015 Telomeres are conserved DNA-protein structures at the termini of eukaryotic chromosomes which contribute to maintenance of genome integrity, and their shortening leads to cell senescence, with negative consequences for organismal functions.
Marco Parolini +8 more
doaj +1 more source
Telomere length determinants in childhood [PDF]
Clinical Chemistry and Laboratory Medicine (CCLM), 2019 Abstract Telomere length (TL) is a dynamic marker that reflects genetic predispositions together with the environmental conditions of an individual. It is closely related to longevity and a number of pathological conditions. Even though the extent of telomere research in children is limited compared to that of adults, there have been a ...
Gorenjak, Vesna +3 more
openaire +2 more sources
Environmental Health, 2021 Background Environmental chemical exposures can affect telomere length, which in turn has been associated with adverse health outcomes including cancer. Firefighters are occupationally exposed to many hazardous chemicals and have higher rates of certain ...
Cassidy Clarity +8 more
doaj +1 more source