Results 41 to 50 of about 77,174 (152)

The Synergistic Effects of the Combination of Ciprofloxacin and Temozolomide on Human Glioblastoma A-172 Cell Line

Middle East Journal of Cancer, 2017
Background: Combination therapy has generated remarkable motivation in the clinical setting since it boosts the therapeutic potential of anticancer drugs.
Ashkan Zandi, Taraneh Moini Zanjani, Seyed Ali Ziai, Yalda Khazaei Poul, Mostafa Haji Molla Hoseini   +4 more
doaj  

Inhibition of Cyclin D1 Expression in Human Glioblastoma Cells is Associated with Increased Temozolomide Chemosensitivity

Cellular Physiology and Biochemistry, 2018
Background/Aims: Cyclin D1 (CCND1) is frequently overexpressed in malignant gliomas. We have previously shown ectopic overexpression of CCND1 in human malignant gliomas cell lines.
Danfeng Zhang, Dawei Dai, Mengxia Zhou, Zhenxing Li, Chunhui Wang, Yicheng Lu, Yiming Li, Junyu Wang   +7 more
doaj   +1 more source

Current chemotherapy strategies for adults with IDH-wildtype glioblastoma

Frontiers in Oncology
IntroductionGlioblastoma, despite advancements in molecular evolution, remains incurable and has low survival rates. Currently, two of the most commonly used chemotherapy regimens are temozolomide and CCNU.
Jing Bao, Rui Sun, Zhenjiang Pan, Shepeng Wei   +3 more
doaj   +1 more source

Toxicities and Associated Factors in Patients Receiving Temozolomide-Containing Regimens: A 12-Year Analysis of Hospital Data

Drug Design, Development and Therapy, 2021
Chen Shi,1,2 Xiong Wang,1,2 Changdong Diao,1,2 Haixia Zhu,1,2 Qi Yuan,1,2 Jinmei Liu,1,2 Shijun Li,1,2 Ming Gu,1,2 Yu Zhang1,2 1Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology (HUST), Wuhan,
Shi C, Wang X, Diao C, Zhu H, Yuan Q, Liu J, Li S, Gu M, Zhang Y   +8 more
doaj  

Temozolomide enhances PARP inhibitor sensitivity in multiple tumour types.

, 2015
List of cell lines screened against a combination of olaparib and temozolomide. Whether enhancement of PARP inhibitor sensitivity with temozolomide is observed (✔) or not (✖) is indicated.
Jon Travers (818670), Tatiana Mironenko (818674), Laura Richardson (818675), Irina Pshenichnaya (818671), Cyril H. Benes (408440), Michael R. Stratton (561654), Sonja J. Gill (818669), Syd Barthorpe (818673), Fiona A. Kogera (818672), Ultan McDermott (213251), Stephen P. Jackson (119194), Mathew J. Garnett (811548)   +11 more
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Temozolomide in combination with fotemustine in patients with metastatic melanoma

, 2008
Purpose Temozolomide and fotemustine are both active drugs for treating metastatic melanoma. The present study was designed to assess the efficacy and safety of combination therapy with temozolomide + fotemustine in patients with metastatic ...
Tas, Faruk, Topuz, Erkan, Camlica, Hakan
core   +1 more source

List of temozolomide (TMZ)-mediated microRNAs.

, 2016
List of temozolomide (TMZ)-mediated microRNAs.
Cheng-Wei Lin (1668613), Cheng-Kuei Chang (3366413), Kuo-Hao Ho (3366419), Chwen-Ming Shih (156200), Peng-Hsu Chen (3366416), Ku-Chung Chen (334175), Ann-Jeng Liu (3168012), Chia-Hsiung Cheng (211531), Chin-Cheng Lee (156187)   +8 more
core   +1 more source

USE OF THE COMBINATION COMPRISING TEMOZOLOMIDE AND TNF-ALPHA FOR TREATING GLIOBLASTOMA [PDF]

, 2023
Disclosed are methods of synergistically inhibiting growth of a glioma cell comprising contacting the cell with temozolomide and TNFα, or with temozolomide, TNFα, and radiation.

core  

Mutations in the PIK3C2B, ERBB3, KIT, and MLH1 Genes and Their Relationship with Resistance to Temozolomide in Patients with High-Grade Gliomas

Biomedicines
Introduction. The treatment for patients with high-grade gliomas includes surgical resection of tumor, radiotherapy, and temozolomide chemotherapy. However, some patients do not respond to temozolomide due to a methylation reversal mechanism by the ...
León Darío Ortiz Gómez, Heidy Johanna Contreras Martínez, David Andrés Galvis Pareja, Sara Vélez Gómez, Jorge Emilio Salazar Flórez, Fernando P. Monroy, Ronald Guillermo Peláez Sánchez   +6 more
doaj   +1 more source

Table_2_Identification and verification of the temozolomide resistance feature gene DACH1 in gliomas.xlsx

, 2023
IntroductionThe most important chemotherapy treatment for glioma patients is temozolomide. However, the development of drug resistance severely restricts the use of temozolomide.
Qiang Gu (330633), Lang Li (91927), Yifan Gan (14728054), Fa-yan Dong (13772233), Xue-feng Wang (13772245), Jiahao Yao (5439854), Xinyu Wang (341591), Shuhuai Zhou (14728057)   +7 more
core   +1 more source