Results 81 to 90 of about 805,115 (152)

Photobiomodulation Enhances Tendon Regeneration: A Systematic Review and Meta‐analysis of Preclinical Studies

Arthroscopy, Sports Medicine, and Rehabilitation, Volume 8, Issue 4, August 2026.
Purpose To evaluate the preclinical evidence supporting the efficacy of photobiomodulation therapies in tendon regeneration. Methods A comprehensive literature search was conducted in MEDLINE, ScienceDirect, and Google Scholar to identify in vivo animal studies evaluating photobiomodulation therapies for tendon healing.
Yose Waluyo, Diah Nurul Islami Muchsin, Muthiah Nur Afifah, Yaldi Rosadi, M. Salas Al Aldi   +4 more
wiley   +1 more source

In Vivo Response to Electrocompacted Tendon‐Derived Thread Scaffolds During Tendon Repair

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
ABSTRACT Tendon injuries remain a major clinical challenge due to the tissue's limited regenerative capacity and poor remodeling of current allograft‐based therapies. To address these limitations, we developed a tendon‐derived thread (TDT) scaffold by electrocompacting decellularized tendon powder into aligned threads, which were subsequently woven ...
Joohee Choi, Phillip McClellan, Maximilian Zernic, Kamal Gautam, James M. Anderson, Ozan Akkus   +5 more
wiley   +1 more source

Transcriptomic and functional comparison of adipose-and bone marrow-derived mesenchymal stem cells for tendon regeneration

Stem Cell Research & Therapy
Background Tendons are specialized connective tissues with limited intrinsic healing properties due to hypovascularity and low metabolic activity. Mesenchymal stem cells (MSCs) possess regenerative potential for tendon injuries. Among the diverse sources
Hadeer Khaled, Mohammed Zayed, Bumseok Kim, Byung-Hoon Jeong, Sang-Ik Oh   +4 more
doaj   +1 more source

Effect of Uniaxial Tensile Cyclic Loading Regimes on Matrix Organization and Tenogenic Differentiation of Adipose-Derived Stem Cells Encapsulated within 3D Collagen Scaffolds

Stem Cells International, 2017
Adipose-derived mesenchymal stem cells have become a popular cell choice for tendon repair strategies due to their relative abundance, ease of isolation, and ability to differentiate into tenocytes.
Gayathri Subramanian, Alexander Stasuk, Mostafa Elsaadany, Eda Yildirim-Ayan   +3 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, Volume 15, Issue 28, 24 July 2026.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

The optimal mechanical condition in stem cell-to-tenocyte differentiation determined with the homogeneous strain distributions and the cellular orientation control

Biology Open, 2019
In tendon tissue engineering, mechanical stimulus-induced differentiation is one of the most attractive techniques for stem cell-to-tenocyte differentiation in terms of cost, safety and simplicity.
Yasuyuki Morita, Toshihiro Sato, Kouji Higashiura, Yusho Hirano, Fuga Matsubara, Kanau Oshima, Koji Niwa, Yuhki Toku, Guanbin Song, Qing Luo, Yang Ju   +10 more
doaj   +1 more source

Serum Advanced Glycation End Products as Drivers of Poor Tendon Outcomes in Diabetes? An Emerging Hypothesis and Narrative Review

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Tendon injuries in diabetes heal poorly, with unclear drivers of extracellular matrix disruption and altered mechanics. This narrative review synthesizes in vitro, animal, and human studies, highlighting serum advanced glycation end products as potential systemic contributors.
Eric J. Gutierrez, Lauren E. Mitevski, Jacob M. Haus, Chad C. Carroll   +3 more
wiley   +1 more source

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

Advanced NanoBiomed Research, Volume 6, Issue 6, June 2026.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo, Simone Micalizzi, Girish Pattappa, Philipp Stahlhut, Jürgen Groll, Carmelo De Maria, Denitsa Docheva, Giovanni Vozzi   +7 more
wiley   +1 more source

Marine silicon for biomedical sustainability

BMEMat, Volume 4, Issue 2, June 2026.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Different combinations of growth factors for the tenogenic differentiation of bone marrow mesenchymal stem cells in monolayer culture and in fibrin-based three-dimensional constructs

, 2017
Tendon injuries are severe burdens in clinics. The poor tendon healing is related to an ineffective response of resident cells and inadequate vascularization.
V. Granata, M. Bottagisio, Valentina Granata, Giuseppe Talò, Arianna Barbara Lovati, G. Talò, C. Bazzocchi, S. Lopa, Matteo Moretti, Silvia Lopa, Chiara Bazzocchi, M. Moretti, Marta Bottagisio, A. Barbara Lovati   +13 more
core   +1 more source