Results 61 to 70 of about 1,779 (108)

Subacromial bursa augmentation in arthroscopic rotator cuff repair: Clinical and doppler ultrasound assessment—A preliminary study

Journal of Experimental Orthopaedics, Volume 13, Issue 2, April 2026.
Bursa augmentation in arthroscopic rotator cuff repair preserved tendon thickness and reduced early postoperative pain without increasing neovascularization. Abstract Purpose To determine whether augmentation with the subacromial bursa influences postoperative tendon healing, particularly regarding morphology and vascularity, after arthroscopic rotator
Florian Freislederer, Mara Dimitriu, David Endell, Laurent Audigé, Daniela Brune, Marco Etter, Markus Scheibel   +6 more
wiley   +1 more source

Tenogenic Cues Are Biochemically and Environmentally Distinct for Tendon Stem Cells and Mesenchymal/Stromal Stem Cells

Stem Cells International
Tendon tissue engineering draws on regenerative medicine principles, offering innovative solutions to address the challenges posed by tendon injuries and degenerative conditions.
Vera Citro, Marta Clerici, Giovanna Della Porta, Nicola Maffulli, Aldo R. Boccaccini, Tina P. Dale, Nicholas R. Forsyth   +6 more
doaj   +1 more source

Enhanced tenogenic potential of tendon-derived mesenchymal stem cells: transcriptomic profiling and in vivo validation

Frontiers in Cell and Developmental Biology
Tendon injuries represent a significant clinical challenge in the treatment of musculoskeletal disorders due to their restricted intrinsic regenerative capacity and propensity for scar tissue formation. Tendon-derived mesenchymal stem cells (TD-MSCs) are
Hadeer Khaled, Mohammed Zayed, Mohammed Zayed, Mohammed Zayed, Bumseok Kim, Byung-Hoon Jeong, Byung-Hoon Jeong, Sang-Ik Oh   +7 more
doaj   +1 more source

Growth Factor-Mediated Tenogenic Induction of Multipotent Mesenchymal Stromal Cells Is Altered by the Microenvironment of Tendon Matrix

Cell Transplantation, 2018
Age-related degenerative changes in tendon tissue represent a common cause for acute tendon pathologies. Although the regenerative potential of multipotent mesenchymal stromal cells (MSC) was reported to restore functionality in injured tendon tissue ...
Susanne Pauline Roth, Susanna Schubert, Patrick Scheibe, Claudia Groß, Walter Brehm, Janina Burk   +5 more
doaj   +1 more source

Tenogenic differentiation of mesenchymal stem cells

Foot & Ankle Orthopaedics, 2018
Category: Basic Sciences/Biologics Introduction/Purpose: Tendon repair has been a challenging issue for surgeons in treating. Although tissue engineering with mesenchymal stem cells (MSC) have been used for tendon repair in both in vivo and in vitro, the
Seung Yeol Lee MD, PhD, Hyang Kim PhD, Kyoung Min Lee MD, PhD   +2 more
doaj   +1 more source

Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling

Bioactive Materials
Tendon repair remains challenging due to its poor intrinsic healing capacity, and stem cell therapy has emerged as a promising strategy to promote tendon regeneration.
Jialin Chen, Renwang Sheng, Qingyun Mo, Ludvig J. Backman, Zhiyuan Lu, Qiuzi Long, Zhixuan Chen, Zhicheng Cao, Yanan Zhang, Chuanquan Liu, Haotian Zheng, Yu Qi, Mumin Cao, Yunfeng Rui, Wei Zhang   +14 more
doaj   +1 more source

Pulsed Electromagnetic Fields Improve Tenogenic Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells: A Potential Strategy for Tendon Repair—An In Vitro Study

Stem Cells International, 2018
Tendon repair is a challenging procedure in orthopaedics. The use of mesenchymal stem cells (MSCs) and pulsed electromagnetic fields (PEMF) in tendon regeneration is still investigational. In this perspective, MSCs isolated from the human umbilical cord (
Antonio Marmotti, Giuseppe Maria Peretti, Silvia Mattia, Laura Mangiavini, Laura de Girolamo, Marco Viganò, Stefania Setti, Davide Edoardo Bonasia, Davide Blonna, Enrico Bellato, Giovanni Ferrero, Filippo Castoldi   +11 more
doaj   +1 more source

EGR1 Induces Tenogenic Differentiation of Tendon Stem Cells and Promotes Rabbit Rotator Cuff Repair

Cellular Physiology and Biochemistry, 2015
Background/Aims: The rate of healing failure after surgical repair of chronic rotator cuff tears is considerably high. The aim of this study was to investigate the function of the zinc finger transcription factor early growth response 1 (EGR1) in the ...
Xu Tao, Junpeng Liu, Lei Chen, You Zhou, Kanglai Tang   +4 more
doaj   +1 more source

Viable tendon neotissue from adult adipose-derived multipotent stromal cells

Frontiers in Bioengineering and Biotechnology
Background: Tendon healing is frequently prolonged, unpredictable, and results in poor tissue quality. Neotissue formed by adult multipotent stromal cells has the potential to guide healthy tendon tissue formation.Objectives: The objective of this study ...
Takashi Taguchi, Mandi Lopez, Catherine Takawira   +2 more
doaj   +1 more source

Nanoscaled and microscaled parallel topography promotes tenogenic differentiation of ASC and neotendon formation in vitro

International Journal of Nanomedicine, 2018
Kaili Zhou,1,* Bei Feng,2,* Wenbo Wang,1,* Yongkang Jiang,1 Wenjie Zhang,1,3 Guangdong Zhou,1,3 Ting Jiang,4,* Yilin Cao,1,3 Wei Liu1,3 1Department of Plastic and Reconstructive Surgery, Shanghai Key Laboratory of Tissue Engineering, Shanghai Ninth ...
Zhou KL, Feng B, Wang WB, Jiang YK, Zhang W, Zhou GD, Jiang T, Cao YL, Liu W   +8 more
doaj