Results 51 to 60 of about 1,779 (108)

Marine silicon for biomedical sustainability

BMEMat, Volume 4, Issue 2, June 2026.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Tenogenic differentiation of mesenchymal stem cells improves healing of linea alba incision

International Journal of Abdominal Wall and Hernia Surgery, 2018
OBJECTIVE: The aim of this study is to investigate the curative effects of mesenchymal stem cells' (MSCs') tenogenic differentiation on Linea alba incision healing.
Dong Wang, Zhen-Ling Ji, Jing-Min Wang, Yu-Yan Tan   +3 more
doaj   +1 more source

Dynamic Culture of TDSCs on a Mechanically Biomimetic PCL/COL Flexible Substrate

FlexTech, Volume 2, Issue 1, Page 23-33, June 2026.
A mechanically biomimetic PCL/COL flexible substrate with electrospun fibers promoted the alignment and tenogenic differentiation of TDSCs under dynamic stimulation. This platform links structural design to cellular response and offers a promising strategy for tendon tissue engineering.
Changyun Wang, Jun Wu, Yuwu Zhang, Yu Wei, Shunze Cao   +4 more
wiley   +1 more source

Engineered Nestin+ TSPC‐Derived Exosomes Promote Tendon Repair Via Metabolic Reprogramming

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Engineered Nestin+ TSPC‐derived exosomes promote tendon repair by reprogramming tenocyte metabolism via the pantothenate‐CoA‐mitochondria axis. They enhance mitochondrial function, reduce senescence and oxidative stress, restoring tendon structure and function in injured and aged models.
Linxiang Cheng, Junyu Guo, Junshu Zhang, Qiangqiang Zheng, Zhixiong Zhang, Jingyao Chen, Jinhan Zhang, Xiao Chen, Zi Yin   +8 more
wiley   +1 more source

Transcriptomic and functional comparison of adipose-and bone marrow-derived mesenchymal stem cells for tendon regeneration

Stem Cell Research & Therapy
Background Tendons are specialized connective tissues with limited intrinsic healing properties due to hypovascularity and low metabolic activity. Mesenchymal stem cells (MSCs) possess regenerative potential for tendon injuries. Among the diverse sources
Hadeer Khaled, Mohammed Zayed, Bumseok Kim, Byung-Hoon Jeong, Sang-Ik Oh   +4 more
doaj   +1 more source

Effect of Uniaxial Tensile Cyclic Loading Regimes on Matrix Organization and Tenogenic Differentiation of Adipose-Derived Stem Cells Encapsulated within 3D Collagen Scaffolds

Stem Cells International, 2017
Adipose-derived mesenchymal stem cells have become a popular cell choice for tendon repair strategies due to their relative abundance, ease of isolation, and ability to differentiate into tenocytes.
Gayathri Subramanian, Alexander Stasuk, Mostafa Elsaadany, Eda Yildirim-Ayan   +3 more
doaj   +1 more source

Dual‐Responsive Hydrogels Engineer Anisotropic Cellular Microenvironment to Modulate Stem Cell Organization and Fate

Small, Volume 22, Issue 36, 26 June 2026.
Collagen peptides hydrogels with tunable mechanical dynamics were developed by employing physical or chemical nanoparticle crosslinkers. Dual‐responsive hydrogels with magnetic‐driven alignment were fabricated under a low magnetic field and rapid UV exposure. The presence of biophysical anisotropy, enhanced biomechanical dynamics, and growth factors—as
Hongjuan Weng, Wen Chen, Lei He, Timo Rademakers, Sabine van Rijt, Monize C. Decarli, Katrien V. Bernaerts, Lorenzo Moroni   +7 more
wiley   +1 more source

The optimal mechanical condition in stem cell-to-tenocyte differentiation determined with the homogeneous strain distributions and the cellular orientation control

Biology Open, 2019
In tendon tissue engineering, mechanical stimulus-induced differentiation is one of the most attractive techniques for stem cell-to-tenocyte differentiation in terms of cost, safety and simplicity.
Yasuyuki Morita, Toshihiro Sato, Kouji Higashiura, Yusho Hirano, Fuga Matsubara, Kanau Oshima, Koji Niwa, Yuhki Toku, Guanbin Song, Qing Luo, Yang Ju   +10 more
doaj   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, Volume 9, Issue 5, Page 898-913, May 2026.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Mechanobiology in Stem Cell‐Based Bioprinting

Cell Proliferation, Volume 59, Issue 5, May 2026.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source