Results 21 to 30 of about 4,238,343 (270)
Scientific Reports, 2017 Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) is a major virulence factor that kills leukocytes permitting it’s escape from host immune surveillance. A. actinomycetemcomitans strains can produce high or low levels of toxin.
Vandana Sampathkumar +3 more
doaj +1 more source
International Journal of Hepatology, 2022 Background. Hepatitis B virus (HBV) is the leading cause of liver-related diseases. In Uganda, there is a regional disparity in the HBV burden. Our study was aimed at establishing the circulating genotypes in a low and a high endemic region to give ...
Hussein Mukasa Kafeero +13 more
doaj +1 more source
Genetic polymorphism of the N-terminal region in circumsporozoite surface protein of Plasmodium falciparum field isolates from Sudan [PDF]
Malaria Journal, 2019 AbstractBackgroundMalaria caused byPlasmodium falciparumparasite is still known to be one of the most significant public health problems in sub-Saharan Africa. Genetic diversity of the SudaneseP. falciparumbased on the diversity in the circumsporozoite surface protein (PfCSP) has not been previously studied.
Nouh Saad Mohamed +12 more
openaire +3 more sources
The Transcription Unit Architecture of Streptomyces lividans TK24
Frontiers in Microbiology, 2019 Streptomyces lividans is an attractive host for production of heterologous proteins and secondary metabolites of other Streptomyces species. To fully harness the industrial potential of S.
Yongjae Lee +10 more
doaj +1 more source
Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation. [PDF]
FEBS Open BioHuman ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Nakata E, Li Y, Endo K, Ito K.
europepmc +2 more sources
Bacterial Noncoding RNAs Excised from within Protein-Coding Transcripts
mBio, 2018 Prokaryotic genomes encode a plethora of small noncoding RNAs (ncRNAs) that fine-tune the expression of specific genes. The vast majority of known bacterial ncRNAs are encoded from within intergenic regions, where their expression is controlled by ...
Daniel Dar, Rotem Sorek
doaj +1 more source
PLoS ONE, 2020 ObjectiveIdentify the prevalence of HPV infections in the uterine cervix and oral cavity and HPV16 variants in HIV+ women.MethodsA total of 174 HIV+ women attended an HIV+ specialized clinic in Mexico City.
Milagros Pérez-Quintanilla +11 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2018 Termination of RNA Polymerase II (Pol II) activity serves a vital cellular role by separating ubiquitous transcription units and influencing RNA fate and function.
Courtney Whalen +5 more
doaj +1 more source
Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene [PDF]
, 2008 The 85-kb breast cancer-associated gene BRCA1 is an established tumor suppressor gene, but its regulation is poorly understood. We demonstrate by gene conformation analysis in both human cell lines and mouse mammary tissue that gene loops are imposed on ...
Brown, Melissa A. +9 more
core +1 more source
Genetic variation in N- and C-terminal regions of bovine DNAJA1 heat shock protein gene in African, Asian and American cattle [PDF]
Journal of Genomics, 2018 DNAJA1 or heat shock protein 40 (Hsp40) is associated with heat adaptation in various organisms. We amplified and sequenced a total of 1,142 bp of bovine Hsp40 gene representing the critical N-terminal (NTR) and C-terminal (CTR) regions in representative samples of African, Asian and American cattle breeds.
Ajayi, Oyeyemi O. +8 more
openaire +2 more sources