Results 31 to 40 of about 70,210 (273)

High-Accuracy DNA Sequence Variation Screening by DHPLC

open access: yesBioTechniques, 2000
Genetic maps based on biallelic singlenucleotide polymorphisms amenable to microarray-based genotyping have significantly accelerated the mapping of mono- and multigenic traits in model organisms such as Saccharomyces cerevisiaeand Arabidopsis thaliana ...
Jamie I. Spiegelman   +2 more
doaj   +1 more source

Genetic polymorphism of the serine rich antigen N-terminal region in Plasmodium falciparum field isolates from Brazil [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 2005
In this work we investigated the frequency of polymorphism in exon II of the gene encoding most of the amino-terminal region of the serine rich antigen (SERA) in Plasmodium falciparum field samples. The blood samples were collected from P. falciparum infected individuals in three areas of the Brazilian Amazon.
Riccio, Evelyn Kety Pratt   +8 more
openaire   +4 more sources

The South Asian Genome [PDF]

open access: yes, 2014
The genetic sequence variation of people from the Indian subcontinent who comprise one-quarter of the world's population, is not well described. We carried out whole genome sequencing of 168 South Asians, along with whole-exome sequencing of 147 South ...
Li Yingrui   +200 more
core   +1 more source

Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV Management

open access: yesInternational Journal of Hepatology, 2022
Background. Hepatitis B virus (HBV) is the leading cause of liver-related diseases. In Uganda, there is a regional disparity in the HBV burden. Our study was aimed at establishing the circulating genotypes in a low and a high endemic region to give ...
Hussein Mukasa Kafeero   +13 more
doaj   +1 more source

Genetic polymorphism of the N-terminal region in circumsporozoite surface protein of Plasmodium falciparum field isolates from Sudan [PDF]

open access: yesMalaria Journal, 2019
AbstractBackgroundMalaria caused byPlasmodium falciparumparasite is still known to be one of the most significant public health problems in sub-Saharan Africa. Genetic diversity of the SudaneseP. falciparumbased on the diversity in the circumsporozoite surface protein (PfCSP) has not been previously studied.
Nouh Saad Mohamed   +12 more
openaire   +3 more sources

The Transcription Unit Architecture of Streptomyces lividans TK24

open access: yesFrontiers in Microbiology, 2019
Streptomyces lividans is an attractive host for production of heterologous proteins and secondary metabolites of other Streptomyces species. To fully harness the industrial potential of S.
Yongjae Lee   +10 more
doaj   +1 more source

Bacterial Noncoding RNAs Excised from within Protein-Coding Transcripts

open access: yesmBio, 2018
Prokaryotic genomes encode a plethora of small noncoding RNAs (ncRNAs) that fine-tune the expression of specific genes. The vast majority of known bacterial ncRNAs are encoded from within intergenic regions, where their expression is controlled by ...
Daniel Dar, Rotem Sorek
doaj   +1 more source

Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals [PDF]

open access: yes, 2014
Objectives Staphylococcus haemolyticus is an emerging cause of nosocomial infections, primarily affecting immunocompromised patients. A comparative genomic analysis was performed on clinical S.
Kahlke, Tim   +19 more
core   +1 more source

High prevalence of human papillomavirus and European variants of HPV 16 infecting concomitantly to cervix and oral cavity in HIV positive women.

open access: yesPLoS ONE, 2020
ObjectiveIdentify the prevalence of HPV infections in the uterine cervix and oral cavity and HPV16 variants in HIV+ women.MethodsA total of 174 HIV+ women attended an HIV+ specialized clinic in Mexico City.
Milagros Pérez-Quintanilla   +11 more
doaj   +1 more source

RNA Polymerase II Transcription Attenuation at the Yeast DNA Repair Gene, DEF1, Involves Sen1-Dependent and Polyadenylation Site-Dependent Termination

open access: yesG3: Genes, Genomes, Genetics, 2018
Termination of RNA Polymerase II (Pol II) activity serves a vital cellular role by separating ubiquitous transcription units and influencing RNA fate and function.
Courtney Whalen   +5 more
doaj   +1 more source

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