Results 31 to 40 of about 4,238,343 (270)

Molecular diversity and phylogenetic characterization of the invA gene in non-typhoidal Salmonella from domestic animals and wildlife in Zambia [PDF]

open access: yesVeterinary World
Background and Aim: Non-typhoidal Salmonella remains a significant zoonotic pathogen with substantial implications for animal and public health, particularly in regions where domestic animals and wildlife share ecological interfaces. The invasion protein
Charles Miyanda Mubita   +4 more
doaj   +1 more source

Comparative analysis of human DNA extraction methods and mitochondrial DNA HV1 and HV2 haplogroup determination [PDF]

open access: yesKragujevac Journal of Science, 2020
The high integrity of extracted DNA is necessary for the determination of human haplogroups, based on the mitochondrial DNA (mtDNA) marker sequences. The study aims were to isolate the total DNA from selected human samples and establish a protocol that ...
Nikezić Aleksandra G.   +8 more
doaj  

A survey of genetic improvement search spaces [PDF]

open access: yes, 2019
Genetic Improvement (GI) uses automated search to improve existing software. Most GI work has focused on empirical studies that successfully apply GI to improve software's running time, fix bugs, add new features, etc. There has been little research into
Alexander, B   +17 more
core   +1 more source

An Alternative Platform for Protein Expression Using an Innate Whole Expression Module from Metagenomic DNA

open access: yesMicroorganisms, 2019
Many integrated gene clusters beyond a single genetic element are commonly trapped as the result of promoter traps in (meta)genomic DNA libraries. Generally, a single element, which is mainly the promoter, is deduced from the resulting gene clusters and ...
Dae-Eun Cheong   +3 more
doaj   +1 more source

The South Asian Genome [PDF]

open access: yes, 2014
The genetic sequence variation of people from the Indian subcontinent who comprise one-quarter of the world's population, is not well described. We carried out whole genome sequencing of 168 South Asians, along with whole-exome sequencing of 147 South ...
Li Yingrui   +200 more
core   +1 more source

5’ and 3’ untranslated regions strongly enhance performance of geminiviral replicons in Nicotiana benthamiana leaves

open access: yesFrontiers in Plant Science, 2016
We previously reported a recombinant protein production system based on a geminivirus replicon that yields high levels of vaccine antigens and monoclonal antibodies in plants.
Andrew G. Diamos   +2 more
doaj   +1 more source

Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 among Plasmodium vivax Korean isolates [PDF]

open access: yesMalaria Journal, 2012
AbstractBackgroundThe carboxy-terminal 42 kDa region ofPlasmodium vivaxmerozoite surface protein-1 (PvMSP-142) is a leading candidate antigen for blood stage vaccine development. However, this region has been observed to be highly polymorphic among filed isolates ofP. vivax. Therefore it is important to analyse the existing diversity of this antigen in
Kang, Jung-Mi   +8 more
openaire   +4 more sources

Cloning and sequencing of the promoter and terminator regions of the rbcL gene from Gunnera perpensa L.

open access: yes, 2021
Primers were designed based on the chloroplast genome sequence from the cotton Gossypium barbadense L. Specificrestriction sites were included in the primers so as to facilitate the process of vector assembly for future chloroplast transformation ...
Rashid Ismael Hag Ibrahim
core   +1 more source

A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity [PDF]

open access: yesProceedings of the National Academy of Sciences, 2000
Death-associated protein kinase (DAP-kinase) is a Ca +2 /calmodulin-regulated serine/threonine kinase with a multidomain structure that participates in apoptosis induced by a variety of signals.
T, Raveh   +4 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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