Results 11 to 20 of about 126,726 (160)
Somatic mutation testing: the role in differential diagnosis of thyroid neoplasms [PDF]
Эндокринная хирургия, 2019 Background: In the preoperative diagnosis of thyroid tumors the cytological examination of the material of fine needle aspiration biopsy is the gold standard and serves as the basis for planning of treatment strategy.
Vera A. Kachko +5 more
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Expression of tert Prevents ALT in Zebrafish Brain Tumors
Frontiers in Cell and Developmental Biology, 2020 The activation of a telomere maintenance mechanism (TMM) is an essential step in cancer progression to escape replicative senescence and apoptosis.
Aurora Irene Idilli +7 more
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Synthesis of Enantiopure tert-Butanesulfinamide from tert-Butanesulfinyloxazolidinone [PDF]
The Journal of Organic Chemistry, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Qin, Yong +4 more
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The Journal of Pathology: Clinical Research, 2023 Recently, telomerase reverse transcriptase (TERT) gene rearrangements have been identified in neuroblastoma (NB), the typical pathological type of neuroblastic tumours (NTs); however, the prevalence of TERT rearrangements in other types of NT remains ...
Yongbo Yu +12 more
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Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review
Frontiers in Endocrinology, 2020 Telomerase reverse transcriptase (TERT) is the catalytic subunit of the enzyme telomerase and is essential for telomerase activity. Upregulation of TERT expression and resulting telomerase activity occurs in the large majority of malignancies, including ...
Brittany A. McKelvey +5 more
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(R)-N-{2-tert-Butyl-2-[(R)-tert-butylsulfonamido]ethylidene}-tert-butanesulfonamide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 The title compound, C(14)H(30)N(2)O(2)S(2), is the product of the monoaddition reaction of tert-butyl magnesium chloride with bis-[(R)-N-tert-butanesulfinyl]ethanediimine. There are two almost identical mol-ecules in the asymmetric unit, the mol-ecular conformation of which is stabilized by an intra-molecular N-H⋯N hydrogen bond.
Cong-Bin Fan, Xiao-Xia Sun, Yu Hu
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Expression of telomerase reverse transcriptase in peripheral T‐cell lymphoma
Cancer Medicine, 2021 Telomere length is maintained by the activation of telomerase, which causes continuous cell division and proliferation in many carcinomas. A catalytic reverse transcriptase protein (TERT) encoded by the TERT gene plays a critical role in the activation ...
Fumiko Arakawa +13 more
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PLoS ONE, 2023 Telomerase reverse transcriptase (TERT) promoter mutations occur frequently in cancer, have been associated with increased TERT expression and cell proliferation, and could potentially influence therapeutic regimens for melanoma.
Christina Katharina Kuhn +10 more
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Mutations in Non–Small Cell Lung Cancer: Clinicopathologic Features and Prognostic Implications
Clinical Medicine Insights: Oncology, 2023 Introduction: The associations between the clinical characteristics of non–small cell lung cancer (NSCLC) and mutations in telomerase reverse transcriptase ( TERT ) gene remain unclear.
Liu Yang +8 more
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Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms. [PDF]
PLoS Computational Biology, 2014 Cancer cells depend on transcription of telomerase reverse transcriptase (TERT). Many transcription factors affect TERT, though regulation occurs in context of a broader network. Network effects on telomerase regulation have not been investigated, though
Alan E Bilsland +6 more
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