Results 41 to 50 of about 130,112 (263)

Insights into the evolution of mammalian telomerase: Platypus TERT shares similarities with genes of birds and other reptiles and localizes on sex chromosomes

BMC Genomics, 2012
Background The TERT gene encodes the catalytic subunit of the telomerase complex and is responsible for maintaining telomere length. Vertebrate telomerase has been studied in eutherian mammals, fish, and the chicken, but less attention has been paid to ...
Hrdličková Radmila, Nehyba Jiří, Lim Shu Ly, Grützner Frank, Bose Henry R   +4 more
doaj   +1 more source

Über die Reaktion von tert-Butyl(tert-butylimino)phosphan mit tert-Butyl-(tert-butylimino)boran

, 2012
Contrary to the [2 + 2] cycloaddition reaction of aminoiminophosphanes with iminoboranes, the title compounds react to yield the heterocyclic products 7 and 9, the structures of which were determined by means of spectroscopic methods and, in the case of 9, additionally by X-ray structural analysis.
Gudat, Dietrich, Niecke, Edgar, Nieger, Martin, Paetzold, Peter   +3 more
openaire   +1 more source

Integration of Low‐Voltage Nanoscale MoS2 Memristors on CMOS Microchips

Advanced Functional Materials, EarlyView.
This article presents the first monolithic integration of nanoscale MoS2‐based memristors into the back‐end‐of‐line of foundry‐fabricated CMOS microchips in a one‐transistor‐one‐resistor (1T1R) architecture. The MoS2‐based 1T1R cells exhibit forming‐free, nonvolatile resistive switching with ultra‐low operating voltages, low cycle‐to‐cycle variability ...
Jimin Lee, Sofía Cruces, Xiaohua Liu, Yang Chen, Vasilis A. Maroufidis, Janghyun Jo, Lukas Völkel, Dennis Braun, Michael Möller, Leon Brackmann, Holger Kalisch, Michael Heuken, Andrei Vescan, Rafal E. Dunin‐Borkowski, Joachim Mayer, Stefan Wiefels, Max C. Lemme   +16 more
wiley   +1 more source

PIF1 Affects the Proliferation and Apoptosis of Cervical Cancer Cells by Influencing TERT

Cancer Management and Research, 2020
Jiancai Wang,1,* Xiaoyan Zhu,1,* Pian Ying,2 Yingping Zhu2 1Department of Gynaecology and Obstetrics, Jianhu Hospital Affiliated to Nantong University, Yancheng, Jiangsu 224700, People’s Republic of China; 2Department of Obstetrics and Gynecology ...
Wang J, Zhu X, Ying P, Zhu Y
doaj  

Multiplex Modular Nanorobotic Systems with Catalytic Activity under Magnetic Navigation

Advanced Functional Materials, EarlyView.
We present modular nanorobots composed of a magnetic propulsion module and different extension modules carrying functional activities, assembled via DNA base pairing. The system integrates propulsion, optical tracking, enzymatic catalysis, and cell docking in a programmable manner.
Voichita Mihali, Xinan Huang, Lucie Motyckova, Nicolas Moreno Gomez, Michal Skowicki, Cora‐Ann Schoenenberger, Peer Fischer, Cornelia G. Palivan   +7 more
wiley   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

BRAFV600E and TERT promoter mutations and their impact on recurrent papillary thyroid carcinoma progression

Endocrine Connections
Papillary thyroid carcinoma (PTC) is the most prevalent histological subtype of thyroid cancer. However, it remains unclear whether BRAFV600E, TERT promoter (TERT-p), and certain pathological markers, such as loss of polarity/loss of cell cohesiveness ...
Nguyen Thi Nhung, Van Dong Hoang, Zhanna Mussazhanova, Hirokazu Kurohama, Le Ngoc Ha, Katsuya Matsuda, Van Phu Thang Nguyen, Ngo Thi Minh Hanh, Thi Ngoc Anh Nguyen, Masahiro Nakashima   +9 more
doaj   +1 more source

TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas. [PDF]

PLoS ONE, 2014
This study explored the effects of telomerase reverse transcriptase (TERT) promoter mutations on transcriptional activity of the TERT gene under hypoxic and temozolomide (TMZ) treatment conditions, and investigated the status and prognostic value of ...
Chen Chen, Sheng Han, Lingxuan Meng, Zhonghua Li, Xue Zhang, Anhua Wu   +5 more
doaj   +1 more source

Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications

Advanced Functional Materials, EarlyView.
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi, Norma Mallegni, Andrea Dorigato, Mario Milazzo   +3 more
wiley   +1 more source

Light‐Actuated Fiber‐Climbing Inchworm Robot Toward Endoluminal Navigation

Advanced Functional Materials, EarlyView.
A kirigami‐inspired soft inchworm robot harnesses optical energy from a customized side‐emitting optical fiber, guaranteeing its propulsion along the fiber body. The wavelength‐selective responsiveness of dye‐functionalized liquid crystal elastomers and the application of temporal illumination patterns enable sequential control of robot components. The
Antonio Lobosco, Leilei Song, Fan Liu, Yu‐Hsiang Lin, Venkatasubramanian Kalpathy Venkiteswaran, Hao Zeng, Sarthak Misra   +6 more
wiley   +1 more source