Results 51 to 60 of about 130,112 (263)

Accumulation of TERT in mitochondria exerts two opposing effects on apoptosis

FEBS Open Bio, 2023
Telomerase reverse transcriptase (TERT) is a protein that catalyzes the reverse transcription of telomere elongation. TERT is also expected to play a non‐canonical role beyond telomere lengthening since it localizes not only in the nucleus but also in ...
Hiroshi Ebata, Tomohiro Shima, Ryo Iizuka, Sotaro Uemura   +3 more
doaj   +1 more source

Dual‐Mode Magnetic Elastomer for On‐Demand Motion and Degradation

Advanced Functional Materials, EarlyView.
A dual‐mode magnetic elastomer is introduced, enabling DC field‐driven programmable actuation and AC field‐driven magnetothermal degradation. GHz‐range magnetic fields generate ultrafast heating of magnetic nanoparticles that activates cleavage of the silicone elastomer matrix.
Jieun Han, Hyun An, Min‐Ha Oh, Yu‐Lim Lee, Woojin Jeon, Kyung‐Sub Kim, Jae‐Hwan Lee, Seungmin Kang, Yoon‐Nam Kim, Ji‐Won Kang, Daewhan Kim, Min Sang Kwon, Sang‐Koog Kim, Seung‐Kyun Kang   +13 more
wiley   +1 more source

Thyroid carcinoma‐featured telomerase activation and telomere maintenance: Biology and translational/clinical significance

Clinical and Translational Medicine, 2022
Background Telomerase is a ribonucleoprotein complex consisting of a catalytic component telomerase reverse transcriptase (TERT), internal RNA template and other co‐factors, and its essential function is to synthesize telomeric DNA, repetitive TTAGGG ...
Xiaotian Yuan, Huiyang Yuan, Ning Zhang, Tiantian Liu, Dawei Xu   +4 more
doaj   +1 more source

Nanoengineered Binetworks in Multifunctional Anionic Block Polymer Mesoblends for Improved Mechanical Properties

Advanced Functional Materials, EarlyView.
Mesoblends consist of a nanostructured polymer into which a second polymer is imbibed with a selective solvent. In this work, a solvent‐templatable pentablock terpolymer possessing a sulfonated midblock is modified with a hydrophilic polymer that is photocrosslinked in situ, yielding a hierarchical binetwork.
Kacie M. Wells, Ivan Kuzmenko, Reza A. Ghiladi, Richard J. Spontak   +3 more
wiley   +1 more source

Notizen: Di-tert-butylchlorthioarsoran / Di-tert-butylchlorothioarsorane

Zeitschrift für Naturforschung B, 1976
The preparation of the first chlorodiorganylthioarsorane is reported. Amidodi(tertbutyl)arsine and sulfur react to give amidodi(tert-butyl)thioarsorane, which is converted into chlorodi(tert-butyl)thioarsorane by a solution of HCl in ether. Some reactions of chlorodi(tert-butyl)thioarsorane are described.
B. Ross, W. Marzi, G. Wilhelm
openaire   +1 more source

Designed Lewis Acid–Base Passivation for High Performance Perovskite Solar Cells

Advanced Functional Materials, EarlyView.
ABSTRACT Silicon's high cost and long energy payback time remain major barriers to the global expansion of solar power. In contrast, metal–halide perovskites offer abundant, solution‐processable absorbers, and have achieved efficiencies of 25%–30%, positioning them as strong competitors to silicon.
Afna Manaf, Hiba Shahulhameed, Bhabani Sankar Swain, Shengzhong (Frank) Liu, Adel Najar   +4 more
wiley   +1 more source

Hybrid Solar Cell/Triboelectric Nanogenerator Based on Stable Two‐Dimensional Covalent Organic Frameworks

Advanced Functional Materials, EarlyView.
This study highlights the integration of stable two‐dimensional covalent organic framework (COF) films as photoactive layers in hybrid nanoenergy devices. The results demonstrate their capacity to generate electricity under both sunny and rainy conditions, showcasing versatility and resilience.
Joab D. Guerrero, Susana Ramos‐Terrón, Salvador R. G. Balestra, José M. Malagón, David Aparicio, Lucia Velasco, Asterios Charisiadis, Dooshaye Moonshiram, Margarita Darder, Pilar Aranda, Bernd Wicklein, Gustavo de Miguel, Javier Pérez‐Carvajal, Eva M. García‐Frutos   +13 more
wiley   +1 more source

Telomeres control human telomerase (TERT) expression through non-telomeric TRF2

eLife
The function of the human telomerase reverse transcriptase (referred hereafter as TERT) in the synthesis and maintenance of chromosome ends, or telomeres, is widely understood.
Antara Sengupta, Soujanya Vinayagamurthy, Dristhi Soni, Rajlekha Deb, Ananda Kishore Mukherjee, Subhajit Dutta, Jushta Jaiswal, Mukta Yadav, Shalu Sharma, Sulochana Bagri, Shuvra Shekhar Roy, Priya Poonia, Ankita Singh, Divya Khanna, Amit Kumar Kumar Bhatt, Akshay Sharma, Suman Saurav, Rajender K Motiani, Shantanu Chowdhury   +18 more
doaj   +1 more source

Synergistic activation of mutant TERT promoter by Sp1 and GABPA in BRAFV600E-driven human cancers

npj Precision Oncology, 2021
The activating TERT promoter mutations and BRAF V600E mutation are well-established oncogenic alterations in human cancers. Coexistence of BRAF V600E and TERT promoter mutations is frequently found in multiple cancer types, and is strongly associated ...
Yongxing Wu, Liang Shi, Yuelei Zhao, Pu Chen, Rongrong Cui, Meiju Ji, Nongyue He, Maode Wang, Gang Li, Peng Hou   +9 more
doaj   +1 more source

Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features

Advanced Healthcare Materials, EarlyView.
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato, Hanan Abumanhal‐Masarweh, Martí de Cabo, Pablo Guerra, Marilena Hadjidemetriou, Neus Lozano, Kostas Kostarelos   +6 more
wiley   +1 more source