Results 61 to 70 of about 187,148 (306)
PIF1 Affects the Proliferation and Apoptosis of Cervical Cancer Cells by Influencing TERT
Cancer Management and Research, 2020 Jiancai Wang,1,* Xiaoyan Zhu,1,* Pian Ying,2 Yingping Zhu2 1Department of Gynaecology and Obstetrics, Jianhu Hospital Affiliated to Nantong University, Yancheng, Jiangsu 224700, People’s Republic of China; 2Department of Obstetrics and Gynecology ...
Wang J, Zhu X, Ying P, Zhu Y
doaj
Targeting the NCOA3-SP1-TERT axis for tumor growth in hepatocellular carcinoma
Cell Death and Disease, 2020 Hepatocellular carcinoma (HCC) has a high mortality rate and lacks an effective therapeutic target. Elevated expression of human telomerase reverse transcriptase (TERT) is an important hallmark in cancers, but the mechanism by which TERT is activated ...
Wenbin Li +12 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Synthesis and Conformational Property of Tannin-like p-tert-Butylcalix[4]arene 1,3-Diesters Stabilized by Intramolecular Hydrogen Bonds [PDF]
, 2016 Tannin-like p-tert-butylcalix[4]arene 1,3-digallate was synthesized, and its conformational property was investigated by dynamic 1H NMR and X-ray crystallography.
Hisaji Taniguchi (2178308) +2 more
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PLoS Genetics, 2019 Telomerase, particularly its main subunit, the reverse transcriptase, TERT, prevents DNA erosion during eukaryotic chromosomal replication, but also has poorly understood non-canonical functions. Here, in the model social amoeba Dictyostelium discoideum,
Nasna Nassir +2 more
doaj +1 more source
BMC Genomics, 2012 Background The TERT gene encodes the catalytic subunit of the telomerase complex and is responsible for maintaining telomere length. Vertebrate telomerase has been studied in eutherian mammals, fish, and the chicken, but less attention has been paid to ...
Hrdličková Radmila +4 more
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TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas. [PDF]
PLoS ONE, 2014 This study explored the effects of telomerase reverse transcriptase (TERT) promoter mutations on transcriptional activity of the TERT gene under hypoxic and temozolomide (TMZ) treatment conditions, and investigated the status and prognostic value of ...
Chen Chen +5 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley +1 more source
Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions
Advanced Functional Materials, EarlyView.This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian +7 more
wiley +1 more source
Functionalization/passivation of porous graphitic carbon with di-tert-amylperoxide [PDF]
, 2011 Functionalization/passivation of porous graphitic carbon with di-tert ...
RE Olsen (16091135) +9 more
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