Results 21 to 30 of about 126,726 (160)

In vitro Differentiation of Human TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells

Hepatic Medicine: Evidence and Research, 2020
Daniel P Collins, 1 Joel H Hapke, 1 Rajagopal N Aravalli, 2 Clifford J Steer 3, 4 1Cytomedical Design Group, LLC, Saint Paul, MN 55127, USA; 2Department of Electrical and Computer Engineering, College of Science and Engineering, University of Minnesota,
Collins DP, Hapke JH, Aravalli RN, Steer CJ   +3 more
doaj  

Potential Antiaging Effects of DLBS1649, a Centella asiatica Bioactive Extract

Journal of Experimental Pharmacology, 2021
Agung H Karsono,1 Olivia M Tandrasasmita,1 Guntur Berlian,1 Raymond R Tjandrawinata2,3 1Section of Molecular Pharmacology, Research Innovation and Invention, Dexa Laboratories of Biomolecular Sciences, Dexa Medica, Cikarang, West Java 17550, Indonesia ...
Karsono AH, Tandrasasmita OM, Berlian G, Tjandrawinata RR   +3 more
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Über die Reaktion von tert-Butyl(tert-butylimino)phosphan mit tert-Butyl-(tert-butylimino)boran

, 1988
Contrary to the [2 + 2] cycloaddition reaction of aminoiminophosphanes with iminoboranes, the title compounds react to yield the heterocyclic products 7 and 9, the structures of which were determined by means of spectroscopic methods and, in the case of 9, additionally by X-ray structural analysis.
Gudat, Dietrich, Niecke, Edgar, Nieger, Martin, Paetzold, Peter   +3 more
openaire   +1 more source

tert-Butyldimethylsilanol hemihydrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2008
The crystal structure of the title compound, C(6)H(16)OSi·0.5H(2)O, reveals an asymmetric unit containing two mol-ecules of the silanol and a single water mol-ecule. There is evidence of hydrogen bonding between the three mol-ecules in the asymmetric unit.
Barry, Sarah M., Mueller-Bunz, Helge, Rutledge, Peter J.   +2 more
openaire   +3 more sources

Idiopathic Pulmonary Fibrosis and Hypersensitive Pneumonitis: A Fresh View on The Role of Genetic and Epigenetic Factors in The Development and Course of Diseases

Архивъ внутренней медицины
Given their ubiquitous progressive nature and unfavorable prognosis, interstitial lung diseases (ILD), especially such common variants as idiopathic pulmonary fibrosis (IPF) and hypersensitivity pneumonitis (HP), rightly attract considerable attention ...
E. E. Arkhangelskaya, S. V. Lyamina, E. O. Kozhevnikova, I. V. Kozlova, T. G. Shapovalova, G. L. Yurenev   +5 more
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TERT Expression in Pituitary Adenomas [PDF]

Türk Patoloji Dergisi, 2017
Objective: Although pituitary adenomas have benign histomorphological features, some of them may present in an aggressive manner. To predict the behaviour of these tumours, telomerase reverse transcriptase (TERT) activity in pituitary adenomas has been ...
Nuray CAN, Mehmet ÇELİK, Buket YILMAZ BÜLBÜL, Necdet SÜT, Filiz ÖZYILMAZ, Semra AYTÜRK, Sibel GÜLDİKEN, Nurtaç SARIKAŞ, Fulya ÖZ PUYAN, Tülin Deniz YALTA, Ali Kemal KUTLU   +10 more
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Downregulated METTL3 Accumulates TERT Expression that Promote the Progression of Ovarian Endometriosis

Frontiers in Bioscience-Landmark
Background: Endometriosis is a complicated and enigmatic disease that significantly diminishes the quality of life for women affected by this condition.
Fang Li, Hua Tao, Yini Wei, Ru Meng, Yushan Li, Lifang Nie, Yu Zhang, Jinjun Chang   +7 more
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Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations

Epigenetics, 2019
Telomere maintenance is a critical requirement for enabling replicative immortality and tumour development. Here, telomerase expression and activity, telomere length (TL) and potential regulatory factors that can underlie telomerase machinery alterations
Omid Fotouhi, Mehran Ghaderi, Na Wang, Jan Zedenius, Magnus Kjellman, Dawei Xu, C. Christofer Juhlin, Catharina Larsson   +7 more
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Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma

Scientific Reports, 2023
TERT promoter mutations are a hallmark of glioblastoma (GBM). Accordingly, TERT and GABPB1, a subunit of the upstream mutant TERT promoter transcription factor GABP, are being considered as promising therapeutic targets in GBM.
Noriaki Minami, Donghyun Hong, Celine Taglang, Georgios Batsios, Anne Marie Gillespie, Pavithra Viswanath, Nicholas Stevers, Carter J. Barger, Joseph F. Costello, Sabrina M. Ronen   +9 more
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Allele‐specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers

Molecular Oncology, 2020
Telomerase reverse transcriptase (TERT) is pathologically expressed in the vast majority of human cancers, but the epigenetic regulation of its expression is only beginning to be understood.
Teisha J. Rowland, Andrew J. Bonham, Thomas R. Cech   +2 more
doaj   +1 more source