Results 11 to 20 of about 187,148 (306)

TERT promoter mutation and proEx C are useful as a screening tool to predict the malignant behavior of thyroid tumors of uncertain malignant potential

open access: yesPolish Journal of Pathology, 2021
Gray zone thyroid tumors for which benignity or malignancy cannot be assessed are constantly increasing and accurate prediction of their malignant behavior is vital to avoid both violent surgical intervention for benign tumors and lax treatment of ...
Mohamed A. Alabiad   +5 more
doaj   +1 more source

Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma [PDF]

open access: yesNeuro-Oncology, 2022
Abstract Background TERT promoter mutations are observed in 80% of wild-type IDH glioblastoma (GBM). Moreover, the upstream TERT transcription factor GABPB1 was recently identified as a cancer-specific therapeutic target for tumors harboring a TERT promoter mutation.
Noriaki Minami   +13 more
openaire   +3 more sources

Non-classical early lanthanide(II) tris(di-tert-butylcyclopentadienyl) complexes [PDF]

open access: yes, 2023
Research data for Non-classical early lanthanide(II) tris(di-tert-butylcyclopentadienyl ...
David Mills (9719114)
core   +1 more source

Prognostic value of somatic mutation testing and different methods of treatment of low-risk differentiated thyroid cancer [PDF]

open access: yesЭндокринная хирургия, 2019
Background: Using molecular testing for prediction the course of the disease could possibly help doctors in making therapeutic decisions about the management of patients, because it remains controversial issues in low-risk differentiated thyroid cancer ...
Vera A. Kachko   +2 more
doaj   +1 more source

DataSheet1_Simultaneous Removal and Extraction of Bisphenol A and 4-tert-butylphenol From Water Samples Using Magnetic Chitosan Particles.docx [PDF]

open access: yes, 2022
Magnetic chitosan (MC) was used as an ecofriendly and potential adsorbent for the removal of bisphenol-A and 4-tert-butylphenol from water samples.
Jasmin Shah (2570668)   +3 more
core   +1 more source

TERT promoter mutations and monoallelic activation of TERT in cancer [PDF]

open access: yesOncogenesis, 2015
AbstractHere we report that promoter mutations in telomerase (TERT), the most common noncoding mutations in cancer, give rise to monoallelic expression of TERT. Through deep RNA sequencing, we find that TERT activation in human cancer cell lines can occur in either mono- or biallelic manner.
Huang, F W   +7 more
openaire   +4 more sources

Synthesis of Enantiopure tert-Butanesulfinamide from tert-Butanesulfinyloxazolidinone [PDF]

open access: yesThe Journal of Organic Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Qin, Yong   +4 more
openaire   +5 more sources

Somatic mutation testing: the role in differential diagnosis of thyroid neoplasms [PDF]

open access: yesЭндокринная хирургия, 2019
Background: In the preoperative diagnosis of thyroid tumors the cytological examination of the material of fine needle aspiration biopsy is the gold standard and serves as the basis for planning of treatment strategy.
Vera A. Kachko   +5 more
doaj   +1 more source

Mechanisms of Reactivation and Its Interaction with [PDF]

open access: yesEndocrinology and Metabolism, 2020
The telomerase reverse transcriptase (TERT) gene, which is repressed in most differentiated human cells, can be reactivated by somatic TERT alterations and epigenetic modulations.
Young Shin Song, Young Joo Park
doaj   +1 more source

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers [PDF]

open access: yes, 2011
Genetic variation at the TERT-CLPTM1L locus at 5p15.33 is associated with susceptibility to several cancers, including epithelial ovarian cancer (EOC). We have carried out fine-mapping of this region in EOC which implicates an association with a single
Chaiwerawattana, A   +339 more
core   +1 more source

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