Results 11 to 20 of about 130,112 (263)
Polish Journal of Pathology, 2021 Gray zone thyroid tumors for which benignity or malignancy cannot be assessed are constantly increasing and accurate prediction of their malignant behavior is vital to avoid both violent surgical intervention for benign tumors and lax treatment of ...
Mohamed A. Alabiad +5 more
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Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma [PDF]
Neuro-Oncology, 2022 Abstract Background TERT promoter mutations are observed in 80% of wild-type IDH glioblastoma (GBM). Moreover, the upstream TERT transcription factor GABPB1 was recently identified as a cancer-specific therapeutic target for tumors harboring a TERT promoter mutation.
Noriaki Minami +13 more
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Prognostic value of somatic mutation testing and different methods of treatment of low-risk differentiated thyroid cancer [PDF]
Эндокринная хирургия, 2019 Background: Using molecular testing for prediction the course of the disease could possibly help doctors in making therapeutic decisions about the management of patients, because it remains controversial issues in low-risk differentiated thyroid cancer ...
Vera A. Kachko +2 more
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TERT promoter mutations and monoallelic activation of TERT in cancer [PDF]
Oncogenesis, 2015 AbstractHere we report that promoter mutations in telomerase (TERT), the most common noncoding mutations in cancer, give rise to monoallelic expression of TERT. Through deep RNA sequencing, we find that TERT activation in human cancer cell lines can occur in either mono- or biallelic manner.
Huang, F W +7 more
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Mechanisms of Reactivation and Its Interaction with [PDF]
Endocrinology and Metabolism, 2020 The telomerase reverse transcriptase (TERT) gene, which is repressed in most differentiated human cells, can be reactivated by somatic TERT alterations and epigenetic modulations.
Young Shin Song, Young Joo Park
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Synthesis of Enantiopure tert-Butanesulfinamide from tert-Butanesulfinyloxazolidinone [PDF]
The Journal of Organic Chemistry, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Qin, Yong +4 more
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Somatic mutation testing: the role in differential diagnosis of thyroid neoplasms [PDF]
Эндокринная хирургия, 2019 Background: In the preoperative diagnosis of thyroid tumors the cytological examination of the material of fine needle aspiration biopsy is the gold standard and serves as the basis for planning of treatment strategy.
Vera A. Kachko +5 more
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Expression of tert Prevents ALT in Zebrafish Brain Tumors
Frontiers in Cell and Developmental Biology, 2020 The activation of a telomere maintenance mechanism (TMM) is an essential step in cancer progression to escape replicative senescence and apoptosis.
Aurora Irene Idilli +7 more
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tert-Butylaminium phosphite [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the title compound, C(4)H(12)N(+)·H(2)PO(3) (-), the components are linked by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds, resulting in a two-dimensional framework.
Jian, Fang-Fang, Zhang, Jun-Li
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The Journal of Pathology: Clinical Research, 2023 Recently, telomerase reverse transcriptase (TERT) gene rearrangements have been identified in neuroblastoma (NB), the typical pathological type of neuroblastic tumours (NTs); however, the prevalence of TERT rearrangements in other types of NT remains ...
Yongbo Yu +12 more
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