Results 101 to 110 of about 8,803 (251)
What makes the kidney so tolerant?
The Journal of Clinical InvestigationVarious organ allografts differ in their propensity to be spontaneously accepted without any immunosuppressive treatment. Understanding the mechanisms behind these differences can aid in managing alloimmune responses in general.
Paolo Molinari, Paolo Cravedi
doaj +1 more source
The Anatomical Record, EarlyView.Gross morphology, Light Microscopy and Scanning Electron Microscopy revealed the structural organization of the oropharyngeal cavity of Kinosternon scorpioides scorpioides, characterized by mucous epithelium, epithelial pores, and developed lingual papillae.
Andréa Magalhães Bezerra +7 more
wiley +1 more source
Animal Research and One Health, EarlyView.Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source
Adipose Tissue: A Tertiary Lymphoid Organ: Does It Change with Age? [PDF]
Gerontology, 2020 Frasca D, Blomberg BB.
europepmc +1 more source
Arthritis &Rheumatology, EarlyView.Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
, 2017 The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes.
Changjun Yin +3 more
openaire +3 more sources
Nature CommunicationsKidney injury disrupts the intricate renal architecture and triggers limited regeneration, together with injury-invoked inflammation and fibrosis. Deciphering the molecular pathways and cellular interactions driving these processes is challenging due to ...
Michal Polonsky +11 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi +11 more
wiley +1 more source
Mechanisms of Epstein-Barr virus-associated autoimmunity: a comparative overview
Frontiers in ImmunologyEpstein–Barr virus (EBV) is a ubiquitous herpesvirus, increasingly implicated in the pathogenesis of several autoimmune diseases, such as multiple sclerosis (MS), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). These diseases have both,
Fathima Shabnam +2 more
doaj +1 more source
Cancer in Systemic Sclerosis: Clinical Associations and Prognostic Impact From the EUSTAR Registry
Arthritis &Rheumatology, EarlyView.Objective Cancer represents a major cause of death in systemic sclerosis (SSc). Established risk factors are limited to specific subsets, particularly early diffuse anti‐RNA polymerase III (POLR3)–positive disease, needing further exploration. Methods We performed a nested case‐control study within the European Scleroderma Trials and Research group ...
Antonio Tonutti +52 more
wiley +1 more source