Results 121 to 130 of about 3,969,489 (270)

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

The Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu, Ivan Varga, Răzvan Costin Tudose   +2 more
wiley   +1 more source

Unveiling immune resistance mechanisms in nasopharyngeal carcinoma and emerging targets for antitumor immune response: tertiary lymphoid structures

Journal of Translational Medicine
Nasopharyngeal carcinoma (NPC) is a prevalent malignancy in China, commonly associated with undifferentiated cell types and Epstein-Barr virus (EBV) infection.
Huilin Wang, Yuting Zhan, Jiadi Luo, Weiyuan Wang, Songqing Fan   +4 more
doaj   +1 more source

Morphological description of the oropharyngeal cavity of Kinosternon scorpioides scorpioides (Linnaeus, 1766), (Testudines: Kinosternidae)

The Anatomical Record, EarlyView.
Gross morphology, Light Microscopy and Scanning Electron Microscopy revealed the structural organization of the oropharyngeal cavity of Kinosternon scorpioides scorpioides, characterized by mucous epithelium, epithelial pores, and developed lingual papillae.
Andréa Magalhães Bezerra, Diego Ferreira de Sousa, Luane Botelho, André Luís Nogueira Lima, Érika Branco, Elane Guerreiro Giese, Washington Luís Pereira, Ana Rita de Lima   +7 more
wiley   +1 more source

Advances on tumor-associated tertiary lymphoid structures in immunotherapy

生物医学转化
Tertiary lymphoid structures (TLS) are ectopic lymphoid structures found in non-lymphoid tissues under chronic inflammatory conditions in recent years.
Hu Chupeng, Chen Yun
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Impact of tertiary lymphoid structure-associated biomarkers on pancreatic cancer via a dual-disease analysis of psoriasis and pancreatic cancer

Discover Oncology
Pancreatic cancer (PC), often referred to as the “king of cancers”, has demonstrated limited success with immunotherapies, many of which are still under development.
Hao Yu, Quan Yuan, Liu-Xing Feng, Jia-Huan Xu, Shen-Yuan Zhan, Zhi-min Li, Shuang-Jia Wang   +6 more
doaj   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

T Cell Plasticity in Systemic Lupus Erythematosus Revealed by Large‐Scale T Cell Receptor Repertoire and Transcriptome Studies

Arthritis &Rheumatology, EarlyView.
Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi, Masahiro Nakano, Kaitlyn A. Lagattuta, Mineto Ota, Hiroaki Hatano, Haruka Takahashi, Takahiro Itamiya, Hajime Inokuchi, Soumya Raychaudhuri, Tomohisa Okamura, Keishi Fujio, Kazuyoshi Ishigaki   +11 more
wiley   +1 more source

Preoperative assessment of tertiary lymphoid structures in stage I lung adenocarcinoma using CT radiomics: a multicenter retrospective cohort study

Cancer Imaging
Objective To develop a multimodal predictive model, Radiomics Integrated TLSs System (RAITS), based on preoperative CT radiomic features for the identification of TLSs in stage I lung adenocarcinoma patients and to evaluate its potential in prognosis ...
Xiaojiang Zhao, Yuhang Wang, Mengli Xue, Yun Ding, Han Zhang, Kai Wang, Jie Ren, Xin Li, Meilin Xu, Jun Lv, Zixiao Wang, Daqiang Sun   +11 more
doaj   +1 more source