Results 121 to 130 of about 13,664 (142)
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Cellular and Vascular Components of Tertiary Lymphoid Structures
2018Inflammatory immune cells recruited at the site of chronic inflammation form structures that resemble secondary lymphoid organs (SLO). These are characterized by segregated areas of prevalent T- or B-cell aggregation, differentiation of high endothelial venules, and local activation of resident stromal cells, including lymphatic endothelial cells.
Christopher George, Mueller +3 more
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Tertiary Lymphoid Structures Among the World of Noncanonical Ectopic Lymphoid Organizations
2018Tertiary lymphoid structures (TLOs), also known as ectopic lymphoid structures, are associated with chronic infections and inflammatory diseases. Despite their association with pathology, these structures are actually a normal, albeit transient, component of the immune system and facilitate local immune responses that are meant to mitigate inflammation
Aaron, Silva-Sanchez +2 more
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Tertiary Lymphoid Structures: Allies of Cancer Immunotherapy
ImmunologyABSTRACTImmunotherapy has demonstrated groundbreaking clinical efficacy across diverse cancer types. Nevertheless, its therapeutic potential remains constrained, with only a small subset of patients achieving durable clinical responses. Emerging evidence highlights tertiary lymphoid structures (TLSs), ectopic lymphoid aggregates induced by chronic ...
Xinze Li +6 more
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Molecular and Cellular Requirements for the Assembly of Tertiary Lymphoid Structures
2018At sites of chronic inflammation, recruited immune cells form structures that resemble secondary lymphoid organs (SLOs). Those are characterized by segregated areas of prevalent T- or B-cell aggregation, differentiation of high endothelial venules (HEVs) and local activation of resident stromal cells.
C G, Mueller +3 more
openaire +2 more sources
The Evolving Landscape of Bladder Tertiary Lymphoid Structures
Journal of Urology, 2023Madhuri, Koti, D Robert, Siemens
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Tertiary lymphoid structures and B cells: An intratumoral immunity cycle
Immunity, 2023Wolf H Fridman +2 more
exaly
Tertiary lymphoid structures as hubs of antitumour immunity
Nature Reviews Cancer, 2023Gabriela Sarti Kinker +1 more
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