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Meningeal Immunity, Drainage, and Tertiary Lymphoid Structure Formation

2018
For decades, the brain has been considered an immune-privileged organ, meaning that the brain was mainly ignored by the immune system and that the presence of immune cells, notably of the adaptive arm, was a hallmark of pathological conditions. Over the past few decades, the definition of the immune privilege continues to be refined.
openaire   +2 more sources

Tertiary Lymphoid Structures and Immunotherapy: Challenges and Opportunities

Tertiary lymphoid structures (TLS) are accumulations of lymphoid cells that arise in ectopic sites through the process of lymphoid neogenesis in chronic inflammation in autoimmunity, microbial infections, organ rejection, aging, and cancer. Their cellular composition and function and regulation via members of the lymphotoxin (LT)/tumor necrosis factor (
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Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer

OncoImmunology, 2018
Florian POSCH   +2 more
exaly  

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