Results 21 to 30 of about 7,204 (227)
Tetrazine-Ligated CRISPR sgRNAs for Efficient Genome Editing
, 2022 CRISPR-Cas technology has revolutionized genome editing. Its broad and fast-growing application in biomedical research and therapeutics has led to increased demand for guide RNAs. The synthesis of chemically modified single-guide RNAs (sgRNAs) containing
Jonathan K. Watts +11 more
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s-Tetrazine-Bridged Photochromic Aromatic Framework Material
, 2022 Integrating fluorescent chromophores in aromatic frameworks could not only prevent aggregation-induced quenching caused by the π–π stacking interaction between the chromophore components but also confer new fluorescence properties.
Tao Chen +17 more
core +1 more source
s-Tetrazine-Bridged Photochromic Aromatic Framework Material
, 2022 Integrating fluorescent chromophores in aromatic frameworks could not only prevent aggregation-induced quenching caused by the π–π stacking interaction between the chromophore components but also confer new fluorescence properties.
Tao Chen (75911) +8 more
core +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2020 The polymeric title compound, poly[aquahemi[μ2-3,6-bis(pyrimidin-2-yl)-1,4-dihydro-1,2,4,5-tetrazine](μ3-sulfato)cadmium(II)], [Cd(SO4)(C10H8N8)0.5(H2O)]n, (I), represents an example of a three-dimensional coordination polymer resulting from the reaction
Suwadee Jiajaroen, Kittipong Chainok
doaj +1 more source
Pharmaceuticals, 2022 Bioorthogonal pretargeted imaging using the inverse-electron-demand Diels–Alder (IEDDA) reaction between a tetrazine (Tz) and a trans-cyclooctene (TCO) represents an attractive strategy for molecular imaging via antibodies.
Christoph Bredack +4 more
doaj +1 more source
Biosensors, 2021 Enzyme-linked immunosorbent assay (ELISA) is routinely used to detect biomolecules related to several diseases facilitating diagnosis and monitoring of these, as well as the possibility of decreasing their mortality rate.
Tania García-Maceira +6 more
doaj +1 more source
Tetrazine bioorthogonal chemistry derived in vivo imaging
Frontiers in Molecular Biosciences, 2022 Bioorthogonal chemistry represents plenty of highly efficient and biocompatible reactions that proceed selectively and rapidly in biological situations without unexpected side reactions towards miscellaneous endogenous functional groups.
Gaoxiang Zhao +9 more
doaj +1 more source
3,6-Dimethyl-N1,N4-bis(pyridin-2-yl)-1,2,4,5-tetrazine-1,4-dicarboxamide
Acta Crystallographica Section E, 2012 In the title molecule, C16H16N8O2, four atoms of the tetrazine ring are coplanar, with the largest deviation from the plane being 0.0236 (12) Å; the other two atoms of the tetrazine ring deviate on the same side from this ...
Qun Shen, Yan-Mei Guo, Guo-Wu Rao
doaj +1 more source
Advances in Tetrazine Bioorthogonal Chemistry Driven by the Synthesis of Novel Tetrazines and Dienophiles [PDF]
Accounts of Chemical Research, 2018 Bioorthogonal chemistry has found increased application in living systems over the past decade. In particular, tetrazine bioorthogonal chemistry has become a powerful tool for imaging, detection, and diagnostic purposes, as reflected in the increased number of examples reported in the literature.
Haoxing Wu, Neal K. Devaraj
openaire +2 more sources
Molecules, 2022 Energetic materials constitute one of the most important subtypes of functional materials used for various applications. A promising approach for the construction of novel thermally stable high-energy materials is based on an assembly of polynitrogen ...
Dmitry M. Bystrov +2 more
doaj +1 more source