Synthesis of Novel Triazoles, Tetrazine, Thiadiazoles and Their Biological Activities
Molecules, 2015 An expedient synthesis of novel triazoles, tetrazine and thiadiazoles, using conveniently accessible and commercially available starting materials has been achieved.
Mohammed A. Al-Omair +2 more
doaj +1 more source
Pretargeting of internalizing trastuzumab and cetuximab with a 18F-tetrazine tracer in xenograft models [PDF]
, 2017 Pretargeting-based approaches are being investigated for radioimmunoimaging and therapy applications to reduce the effective radiation burden to the patient.
Airaksinen, Anu +9 more
core +2 more sources
Tailoring Chimeric Ligands for Studying and Biasing ErbB Receptor Family Interactions [PDF]
, 2013 Described is the development and application of a versatile semisynthetic strategy, based on a combination of sortase-mediated coupling and tetrazine ligation chemistry, which can be exploited for the efficient incorporation of tunable functionality into
Amin +39 more
core +1 more source
Equilibrium Structures of Pyrazine, s-Triazine, and s-Tetrazine
, 2019 In recent years, accurate equilibrium (re) structures have been determined for pyridine, pyridazine, and pyrimidine. Here, we report accurate re structures for the structurally related molecules pyrazine, s-triazine, and s-tetrazine, which were obtained ...
Breidung, J., Thiel, W.
core +1 more source
Controlled Orientation of Active Sites in a Nanostructured Multienzyme Complex [PDF]
, 2016 Multistep cascade reactions in nature maximize reaction efficiency by co-assembling related enzymes. Such organization facilitates the processing of intermediates by downstream enzymes.
A Sachdeva +43 more
core +2 more sources
Genetic code expansion for chemosensing and chemical actuation of biological functions
Bulletin of the Korean Chemical Society, EarlyView.Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley +1 more source
Rotational distributions following van der Waals molecule dissociation: Comparison between experiment and theory for benzene-Ar [PDF]
, 2005 Rebecca K. Sampson, Susan M. Bellm, Anthony J.
Bellm, Susan +3 more
core +2 more sources
Polymer Chemistry, 2020 Tetrazine- andtrans-cyclooctene-functionalised polypeptides and polypetoids were prepared by ring-opening polymerisation ofN-carboxyanhydrides using the respective functional initiators and shown to react in fast bioorthogonal tetrazine ligations.
Kerstin Johann +8 more
openaire +4 more sources
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Synthesis, biological evaluation, and utility of fluorescent ligands targeting the μ-opioid receptor [PDF]
, 2015 Fluorescently labeled ligands are useful pharmacological research tools for studying receptor localization, trafficking, and signaling processes via fluorescence imaging. They are also employed in fluorescent binding assays. This study is centered on the
Briddon, Stephen J. +6 more
core +4 more sources