Results 1 to 10 of about 18,166 (271)

Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids [PDF]

Frontiers in Pharmacology
The triazole antifungals posaconazole and itraconazole can cause pseudohyperaldosteronism with hypertension and hypokalemia, edema, and gynecomastia by inhibiting steroid synthesis and metabolism.
Marie-Christin Jäger, Marie-Christin Jäger, Víctor González-Ruiz, Víctor González-Ruiz, Friedrich L. Joos, Friedrich L. Joos, Denise V. Winter, Julien Boccard, Julien Boccard, Thorsten Degenhardt, Steve Brand, Serge Rudaz, Serge Rudaz, George R. Thompson, Alex Odermatt, Alex Odermatt   +15 more
doaj   +2 more sources

Facile synthesis of tetrazoles catalyzed by the new copper nano-catalyst

Green Chemistry Letters and Reviews, 2020
Despite various methods for preparation of tetrazoles, they are suffering from some disadvantages such as low yield, long reaction times and harsh reaction conditions, and there are still high demands to improve the common procedures to solve problems ...
Vahideh Khorramabadi, Davood Habibi, Somayyeh Heydari   +2 more
doaj   +2 more sources

(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric Organocatalysts of Broad Utility in Organic Synthesis

CHIMIA, 2007
This mini-review concerns the broad application of (S)- and (R)-5-pyrrolidin-2-yl-1H-tetrazoles as organocatalysts. A summary of methods for their synthesis is followed by a discussion of the general reaction mechanism and subsequent analysis of
Deborah A. Longbottom, Vilius Franckevičius, Steven V. Ley   +2 more
doaj   +3 more sources

Substituent Effects on EI-MS Fragmentation Patterns of 5-Allyloxy-1-aryl-tetrazoles and 4-Allyl-1-aryl-tetrazole-5-ones; Correlation with UV-Induced Fragmentation Channels

Molecules, 2021
1,4- and 1,5-disubstituted tetrazoles possess enriched structures and versatile chemistry, representing a challenge for chemists. In the present work, we unravel the fragmentation patterns of a chemically diverse range of 5-allyloxy-1-aryl-tetrazoles and
Alina Secrieru, Rabah Oumeddour, Maria L. S. Cristiano   +2 more
doaj   +1 more source

Investigation of Fe3O4@boehmite NPs as efficient and magnetically recoverable nanocatalyst in the homoselective synthesis of tetrazoles

RSC Advances, 2022
Magnetic boehmite nanoparticles (Fe3O4@boehmite NPs) were synthesized from a hybrid of boehmite and Fe3O4 nanoparticles. At first, boehmite nanoparticles (aluminum oxide hydroxide) were prepared via a simple procedure in water using commercially ...
Parisa Moradi
semanticscholar   +1 more source

Nanomaterial catalyzed green synthesis of tetrazoles and its derivatives: a review on recent advancements

RSC Advances, 2021
Tetrazoles are indispensable nitrogen containing heterocyclic scaffolds that offer a broad spectrum of applications in various domains such as medicinal chemistry, high energy material science, biochemistry, pharmacology etc.
Suman Swami, S. Sahu, R. Shrivastava
semanticscholar   +1 more source

Photochemistry of 1-Phenyl-4-Allyl-Tetrazol-5-One: A Theoretical Study Contribution towards Mechanism Elucidation

Applied Sciences, 2021
The photodegradation mechanism of 1-phenyl-4-allyl-tetrazol-5-one has been studied using (time-dependent) density functional theory with the M06-HF, B3LYP, and PBE0 functionals and the VDZ basis set.
Amilcar Duque-Prata, Carlos Serpa, Pedro J. S. B. Caridade   +2 more
doaj   +1 more source

Ultrasound-Assisted Ugi-Azide Multicomponent Reaction for the Synthesis of 1,5-Disubstituted Tetrazoles

Chemistry Proceedings, 2023
The Ugi-azide MCR (UA) is one of the most efficient methods for the synthesis of 1,5-disubstituted-1H-tetrazoles (1,5-DS-T). Complex drug-like scaffolds incorporating tetrazoles have demonstrated a wide range of therapeutic benefits such as anti ...
Alejandro Corona-Díaz, Sandra C. Ramírez-López, David Calderón-Rangel, Cristian Saldaña-Arredondo, Rocío Gámez-Montaño   +4 more
doaj   +1 more source

Immobilization of La on THH-CO2H@Fe3O4 nanocomposite for the synthesis of one‐pot multicomponent reactions

Materials Research Express, 2021
The current research represents a facile and competent methodology in the development of a novel magnetic nanocatalyst. This composite was synthesized by immobilizing La on Fe _3 O _4 nanoparticles pre-functionalized with tetrahydroharman-3-carboxylic ...
Taiebeh Tamoradi, AfsanehTaheri Kal-Koshvandi, Bikash Karmakar, Ali Maleki   +3 more
doaj   +1 more source

Synthesis, structure and characterisation of late transition metal complexes with 2-(tetrazol-1-yl)pyridine

Журнал Белорусского государственного университета: Химия, 2022
Complexes [MII(2-pytz)Cl2] (M(II) = Pt, Pd; 2-pytz = 2-(tetrazol-1-yl)pyridine) were synthesised via direct interaction of the corresponding metal chlorides (K2PtCl4 or PdCl2) with 2-pytz under ambient conditions.
Tatiyana V. Serebryanskaya, Hanna A. Belavusava, Yuri V. Grigoriev, Sergei V. Voitekhovich, Ludmila S. Ivashkevich, Oleg A. Ivashkevich   +5 more
doaj   +1 more source