Results 11 to 20 of about 17,991 (268)
Tetrazoles via Multicomponent Reactions [PDF]
Chemical Reviews, 2019 Tetrazole derivatives are a prime class of heterocycles, very important to medicinal chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide moieties but also to their metabolic stability and other beneficial physicochemical properties.
Constantinos G. Neochoritis +2 more
openaire +5 more sources
Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids. [PDF]
Front PharmacolThe triazole antifungals posaconazole and itraconazole can cause pseudohyperaldosteronism with hypertension and hypokalemia, edema, and gynecomastia by inhibiting steroid synthesis and metabolism.
Jäger MC +9 more
europepmc +2 more sources
Facile synthesis of tetrazoles catalyzed by the new copper nano-catalyst
Green Chemistry Letters and Reviews, 2020 Despite various methods for preparation of tetrazoles, they are suffering from some disadvantages such as low yield, long reaction times and harsh reaction conditions, and there are still high demands to improve the common procedures to solve problems ...
Vahideh Khorramabadi +2 more
doaj +2 more sources
One-pot synthesis, computational chemical study, molecular docking, biological study, and in silico prediction ADME/pharmacokinetics properties of 5-substituted 1H-tetrazole derivatives. [PDF]
Sci Rep, 2023 An efficient synthesis of 5-substituted 1H-tetrazoles was successfully achieved through one-pot multi-component condensation reactions of some aromatic aldehydes or indolin-2,3-dione with malononitrile and sodium azide using diverse reaction conditions ...
El-Sewedy A +4 more
europepmc +2 more sources
CHIMIA, 2007 This mini-review concerns the broad application of (S)- and (R)-5-pyrrolidin-2-yl-1H-tetrazoles as organocatalysts. A summary of methods for their synthesis is followed by a discussion of the general reaction mechanism and subsequent analysis of
Deborah A. Longbottom +2 more
doaj +3 more sources
Polymethylenetetrazole: Synthesis, Characterization, and Energetic Properties. [PDF]
MoleculesThe tetrazole moiety remains one of the most interesting scaffolds in the development of new high-energy density materials (HEDMs) because of its desired characteristics, such as high nitrogen content and heat of formation (HOF).
Brenjo L +6 more
europepmc +2 more sources
On the Facile Synthesis of Triazaarsoles Using Acyclic Precursors [PDF]
Chemistry – A European Journal, Volume 31, Issue 27, May 14, 2025.Easily accessible dichloroarsanes are suitable precursors for the synthesis of novel triazaarsoles, the arsenic analogues of tetrazoles and triazaphospholes. Our findings pave the way to access and fully investigate such aromatic arsenic heterocycles in detail.
Lilian S. Szych +7 more
wiley +2 more sources
Molecules, 2021 1,4- and 1,5-disubstituted tetrazoles possess enriched structures and versatile chemistry, representing a challenge for chemists. In the present work, we unravel the fragmentation patterns of a chemically diverse range of 5-allyloxy-1-aryl-tetrazoles and
Alina Secrieru +2 more
doaj +1 more source
RSC Advances, 2022 Magnetic boehmite nanoparticles (Fe3O4@boehmite NPs) were synthesized from a hybrid of boehmite and Fe3O4 nanoparticles. At first, boehmite nanoparticles (aluminum oxide hydroxide) were prepared via a simple procedure in water using commercially ...
Parisa Moradi
semanticscholar +1 more source
RSC Advances, 2021 Tetrazoles are indispensable nitrogen containing heterocyclic scaffolds that offer a broad spectrum of applications in various domains such as medicinal chemistry, high energy material science, biochemistry, pharmacology etc.
Suman Swami, S. Sahu, R. Shrivastava
semanticscholar +1 more source