Results 61 to 70 of about 17,991 (268)
Synthesis of 1,5 and 2,5-disubstituted tetrazoles using NiO nanoparticles and their evaluation as antimicrobial agents [PDF]
Treatments of tetrazolate salts prepared in situ from various aldehyde; malononitrile and sodium azide in the presence of NiO nanoparticles with benzyl bromide gave the corresponding 1,5- and 2,5-disubstituted tetrazoles.
Javad Safaei-Ghomi+3 more
doaj +1 more source
A silver-catalyzed regioselective [3 + 2] cycloaddition reaction of PhSO2CF2CHN2 with aryl diazonium salts is described. This protocol enables the straightforward construction of a novel class of difluoromethylated tetrazoles under mild conditions ...
Xing Peng+4 more
semanticscholar +1 more source
Here we report a Ag-catalyzed [3 + 2] cycloaddition reaction between aryl diazonium salts and Seyferth-Gilbert reagent in a regioselective manner. This operationally simple transformation proceeds in an atom-economical way under mild reaction conditions,
Shi-Jing Zhai+3 more
semanticscholar +1 more source
Diazocarbonyl and Related Compounds in the Synthesis of Azoles
Diazocarbonyl compounds have found numerous applications in many areas of chemistry. Among the most developed fields of diazo chemistry is the preparation of azoles from diazo compounds.
Anton Budeev+3 more
doaj +1 more source
VT-1161 and VT-1598 are promising investigational tetrazole antifungals that have shown in vitro and in vivo activity against Candida and other fungi.
A. Nishimoto+8 more
semanticscholar +1 more source
Ruthenium Catalyzed Ortho‐Arylation Reaction of Benzoic Acids with Arylthianthrenium Salts
A catalytic ortho‐arylation method has been developed to convert arylthianthrenium salts into carboxylate‐functionalized biaryls, which can be removed in situ or used for further derivatization. This reaction is broadly applicable to (hetero)arenecarboxylic acids, with excellent functional group compatibility and orthogonality to cross‐couplings ...
Kaiping Wang+9 more
wiley +1 more source
One-Pot Synthesis of Tetrazole–Triazole Bis-Heterocycles via Ugi–Azide Reaction
Bioisosteres of amide bonds such as 4,5-disubstituted-1,2,3-triazoles (4,5-DS-1,2,3-Ts) and 1,5-disubstituted tetrazoles (1,5-DST) are present in compounds with important biological activities like those that are antineoplastic, antibacterial, antifungal,
Fidel Rodriguez-Lopez+3 more
doaj +1 more source
Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis
This review highlights recent advances in mechanochemical methods for multistep organic synthesis, focusing on sequential one‐pot approaches performed by grinding or ball milling. The presented transformations are discussed in terms of efficiency, applicability, and sustainability, assessing both the challenges and potential of solvent‐free one‐pot ...
Nina Biedermann, Michael Schnürch
wiley +1 more source
Semisynthesis of 6β-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction
A semisynthesis of 6β-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of Caesalpinia platyloba by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where
Gabriela Servín-García+7 more
doaj +1 more source