Isocyanide-based multicomponent reactions (IMCRs) allow the construction of relatively complex molecules through a one-pot synthesis. The combination of IMCRs in a consecutive or sequential fashion further extends the complexity of the molecules obtained.
Angélica de Fátima S. Barreto +2 more
doaj +1 more source
Synthesis of Azoles Condensed with, or Linked to, Nitroxides [PDF]
Nitroxides connected to indoles, tetrazoles, or 1,3,4-oxadiazoles were synthesized by conventional and microwave-assisted cyclization reactions. New approaches to pyrrole-, pyrazole-, and triazoleannulated nitroxides are described.
Bognár, Balázs +4 more
core +1 more source
MMP-13 Selective α-sulfone Hydroxamates: a Survey of P1\u27 Heterocyclic Amide Isosteres [PDF]
Seeking compounds preferentially potent and selective for MMP-13, we reported in the preceding Letter on a series of hydroxamic acids with a flexible benzamide tail groups.(1a) Here, we replace the amide moiety with non-hydrolyzable heterocycles in an ...
Barta, Thomas E. +3 more
core
Involvement of angiotensin II in the remodeling induced by a chronic decrease in blood flow in rat mesenteric resistance arteries [PDF]
Blood flow reduction induces inward remodeling of resistance arteries (RAs). This remodeling occurs in ischemic diseases, diabetes and hypertension. Nonetheless, the effect of flow reduction per se, independent of the effect of pressure or metabolic ...
A.L. Guihot +9 more
core +3 more sources
Synthesis, single crystal analysis, biological and docking evaluation of tetrazole derivatives
Tetrazoles are conjugated nitrogen-rich heterocycles considered as bio-isosteres of carboxylic acids. Tetrazoles owing to their conjugated structures serve as biologically relevant potent scaffolds.
Hamid Aziz +4 more
doaj +1 more source
Nitrile ylides: allenic and propargylic structures from pyrazinylnitrenes. Experimental and theoretical characterization [PDF]
Matrix photolysis of 2-pyrazinyl azides/tetrazolo[1,5-a]pyrazines generates nitrile ylides 15 via pyrazinylnitrenes 13 and triazacycloheptatetraenes 14.
Addicott, Chris +6 more
core +2 more sources
Bipolar Hydrogen Production by Hybrid Water Electrolysis
This review focuses on the recent advances in uniqueness bipolar H2 production from the oxidation of representative small molecules, including 5‐hydroxymethylfurfural, formaldehyde, alcohols, and N‐heterocycle amides. The target electrocatalysts and the underlying mechanisms are discussed in respect to specific substrate oxidation.
Jiachen Li +5 more
wiley +1 more source
Synthesis of Novel (bis‐)1,5‐Disubstituted‐1H‐tetrazole‐Decorated Monomers and Their Respective Polymers via Thiol‐ene Polymerization [PDF]
Meryem S. Akdemir +3 more
openalex +1 more source
New iron tetrazolate frameworks : synthesis temperature effect, thermal behaviour, Mössbauer and magnetic studies [PDF]
The exploration of the FeF3/FeF2-Hamtetraz-HF system in dimethylformamide by solvothermal synthesis evidences two isostructural 3D hybrid fluoroferrates. They are prepared from the same starting mixture at two different synthesis temperatures: 120 °C for
Clark, Lucy Mary +12 more
core +3 more sources
Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri +6 more
wiley +1 more source

