Results 41 to 50 of about 418,971 (241)

The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PDF]

open access: yes, 2015
We assessed the predictive ability of selected biomarkers using N-terminal pro-brain natriuretic peptide (NT-proBNP) as the benchmark and tried to establish a multi-biomarker approach to heart failure (HF) in hypertensive patients. In 120 hypertensive
Agata Bielecka-Dabrowa   +10 more
core   +2 more sources

Pemberian Ekstrak Etanol Daun Salam untuk Menurunkan Ekspresi TGF-β Podosit Glomerulus Tikus Sprague dawley Diabetes Melitus [PDF]

open access: yes, 2014
Latar Belakang : Diabetes melitus merupakan kelompok sindrom metabolik yang dapat mengakibatkan peningkatan growth factor pada glomerulus, salah satunya yaitu ekspresi TGF-β di podosit.
rumaolat, wiwi
core  

Induction of podoplanin by transforming growth factor-β in human fibrosarcoma [PDF]

open access: yes, 2008
Podoplanin/aggrus is increased in tumors and its expression was associated with tumor malignancy. Podoplanin on cancer cells serves as a platelet-aggregating factor, which is associated with the metastatic potential.
Kato Kaneko Mika   +7 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

KADAR KORTISOL, TRANSFORMING GROWTH FACTOR β (TGF-β), SERTA DERAJAT ADHESI PASCA LAPAROSKOPI DAN LAPAROTOMI (Penelitian Eksperimental pada Kelinci yang Dilakukan Abrasi Ileum) [PDF]

open access: yes, 2015
Background: Intraperitoneal adhesions after abdominal surgery occurred in 50-97% cases, and the most cause is laparotomy. This research was done to know the difference between laparoscopy and laparotomy regarding the peritoneal adhesion degree, cortisol ...
Pribadi, Agung
core  

Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer [PDF]

open access: yes, 2018
Wnt-11 promotes cancer cell migration and invasion independently of β-catenin but the receptors involved remain unknown. Here, we provide evidence that FZD8 is a major Wnt-11 receptor in prostate cancer that integrates Wnt-11 and TGF-β signals to promote
Carton, J   +8 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Rat testicular germ cells and sertoli cells release different types of bioactive transforming growth factor beta in vitro

open access: yesReproductive Biology and Endocrinology, 2003
Several in vivo studies have reported the presence of immunoreactive transforming growth factor-β's (TGF-β's) in testicular cells at defined stages of their differentiation.
Themmen Axel PN   +3 more
doaj   +1 more source

Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Immunosuppressant cyclosporine-A induces gingival hyperplasia, which is characterized by increased fibroblast proliferation and overproduction of extracellular matrix components and regulated by transforming growth factor-beta (TGF-β).
Yi Chung, Earl Fu
doaj   +1 more source

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells. [PDF]

open access: yes, 2017
Helminth parasites defy immune exclusion through sophisticated evasion mechanisms, including activation of host immunosuppressive regulatory T (Treg) cells.
A Alcami   +65 more
core   +7 more sources

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