Results 1 to 10 of about 528,953 (331)
Th1, Th2, and Th17 cytokines in systemic lupus erythematosus
Autoimmunity, 2020 Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the breakdown of immune tolerance leading to excessive inflammation and tissue damage.
Farhana Muhammad Yusoff +2 more
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Modes of the initiation of T cell-mediated immune responses [PDF]
Medical ReviewT cell-mediated immune response is the center of adaptive immunity. Despite more than five decades of research, the knowledge of mechanisms drives the initiation of T cell-mediated immune response is still limited due to the complexity of T cell-mediated
Li Long, Yao Zhi
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Cell Reports, 2017 Recent data indicate that the differentiation state of Th1 cells determines their protective capacity against tuberculosis. Therefore, we examined the role of Th1-polarizing factors in the generation of protective and non-protective subsets of Mtb ...
Michelle A. Sallin +5 more
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Evaluation of IFN-γ and T-bet Expression Levels as Possible Molecular Markers of Schizophrenia [PDF]
Journal of Cell and Molecular Research, 2020 Schizophrenia is an irritating mental disorder that affects around 1% of the world's population. The immune system contributes to the onset of the disease, particularly through production and secretion of some cytokines.
Roghaye Lorestani +3 more
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T helper cell subsets and related target cells in acute COVID-19
Инфекция и иммунитет, 2022 Current review presents a brief overview of the immune system dysregulation during acute COVID-19 and illustrates the main alterations in peripheral blood CD4+ T-cell (Th) subsets as well as related target cells.
I. V. Kudryavtsev +2 more
doaj +1 more source
Review – Helicobacter: inflammation, immunity and vaccines [PDF]
Microbiota in Health and Disease, 2021 Helicobacter pylori is a bacterium that colonizes the human stomach and is the risk factor for severe gastroduodenal diseases, such as gastric cancer, gastric lymphoma, autoimmune gastritis and peptic ulcer. H.
M. D’Elios, M. de Bernard
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Российский кардиологический журнал, 2022 Aim. To analyze the relationship of blood lipid profile parameters, including the level of lipoprotein(a) (Lp(a)), and the content of circulating CD4+ T-lymphocytes with premature coronary artery disease (CAD).Material and methods.
A. Yu. Filatova +6 more
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Polysaccharides regulate Th1/Th2 balance: A new strategy for tumor immunotherapy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023 T helper (Th) cells have received extensive attention owing to their indispensable roles in anti-tumor immune responses. Th1 and Th2 cells are two key subsets of Th cells that exist in relative equilibrium through the secretion of cytokines that suppress
Qihang Shang +5 more
semanticscholar +1 more source
Recent advances in understanding the Th1/Th2 effector choice
Faculty Reviews, 2021 For over 35 years since Mosmann and Coffman proposed the seminal “type 1 T helper (Th1)/type 2 T helper (Th2)” hypothesis in 1986, the immunological community has appreciated that naïve CD4 T cells need to make important decisions upon their activation ...
M. Butcher, Jinfang Zhu
semanticscholar +1 more source
An in silico approach for modelling T-helper polarizing iNKT cell agonists [PDF]
, 2014 Many analogues of the glycolipid alpha-galactosylceramide (α-GalCer) are known to activate iNKT cells through their interaction with CD1d-expressing antigen-presenting cells, inducing the release of Th1 and Th2 cytokines. Because of iNKT cell involvement
ASPESLAGH, SANDRINE +9 more
core +7 more sources