Results 91 to 100 of about 230,695 (309)

Omnidirectional Transmissive Acoustic Metasurfaces Based on Goldberg Polyhedra

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces omnidirectional acoustic metasurfaces capable of manipulating wavefronts in multiple arbitrary directions simultaneously. A full‐stack pipeline for design, optimization, and fabrication is presented to construct near‐spherical holograms based on Goldberg polyhedra.
Andrea Achilleos   +3 more
wiley   +1 more source

IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.

open access: yesPLoS Pathogens, 2013
The IL-27R, WSX-1, is required to limit IFN-γ production by effector CD4⁺ T cells in a number of different inflammatory conditions but the molecular basis of WSX-1-mediated regulation of Th1 responses in vivo during infection has not been investigated in
Ana Villegas-Mendez   +9 more
doaj   +1 more source

Ivermectin-facilitated immunity in onchocerciasis: activation of parasite-specific th1 type responses with subclinicalOnchocerca volvulusinfection [PDF]

open access: bronze, 1994
Peter T. Soboslay   +8 more
openalex   +1 more source

Nanozymes for Treating Ocular Diseases

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 8, March 25, 2025.
Nanozymes, with their nanoscale size and enzyme‐like activities, can reduce inflammation and oxidative stress associated with various ocular diseases. Recent research explores their integration with soft materials, nanoparticles, and drug delivery systems, promising enhanced therapeutic outcomes.
Ka‐Ying Wong   +2 more
wiley   +1 more source

Th1 cell anergy and blockade in G1a phase of the cell cycle. [PDF]

open access: bronze, 1993
Katabarwa Murenzi Gilbert   +1 more
openalex   +1 more source

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden   +5 more
wiley   +1 more source

PRMT5 regulates epigenetic changes in suppressive Th1-like iTregs in response to IL-12 treatment

open access: yesFrontiers in Immunology
BackgroundInduced regulatory T cells (iTregs) are a heterogeneous population of immunosuppressive T cells with therapeutic potential. Treg cells show a range of plasticity and can acquire T effector-like capacities, as is the case for T helper 1 (Th1 ...
Nidhi Jadon   +4 more
doaj   +1 more source

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel   +15 more
wiley   +1 more source

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