Results 21 to 30 of about 319,332 (247)

Inactivated herpes simplex virus-1 vaccine formulated in aqueous and alcoholic extracts of propolis boosts cellular and IgG responses [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): In this study, the adjuvant activity of aqueous and alcoholic extracts of propolis was examined on the inactivated herpes simplex virus-1 (HSV-1).Materials and Methods: BALB/C mice were administered with inactivated (HSV-1; the KOS strain ...
Sanaz Mojarab, Pegah Karimi, Delavar Shahbazzadeh, Majid Moghbeli, Kamran Pooshang Bagheri, Arezoo Beig Parikhani, Rada Dehghan, Ehsan Zafari, Amir Moravej, Mohammad Hassan Pouriyayevali, Seyedeh Faranak Mirtalebi, Mahdi Pakjoo, Shaghayegh Yazdani, Meghdad Abdollahpour-alitappeh, Mehdi Mahdavi   +14 more
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IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.

Journal of Immunology, 1991
Murine IL-10 (cytokine synthesis inhibitory factor) inhibits cytokine production by Th1 cell clones when they are activated under conditions requiring the presence of APC. By preincubating APC with IL-10, we demonstrate that IL-10 acts principally on APC
D. Fiorentino, A. Zlotnik, P. Vieira, T. Mosmann, M. Howard, K. Moore, A. O’Garra   +6 more
semanticscholar   +1 more source

Spatiotemporal Cellular Networks Maintain Immune Homeostasis in the Lung

European Medical Journal Respiratory, 2020
A dynamic and intricately connected tissue-resident immune cell network continuously monitors the lungs, which are incessantly subjected to external environmental insults.
Jessica G. Borgeredo
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The attenuation effect of low piperine Piper nigrum extract on doxorubicin-induced toxicity of blood chemical and immunological properties in mammary tumour rats

Pharmaceutical Biology, 2022
Context Many natural extracts have been shown to minimize the toxicity of doxorubicin (Dox). Low piperine Piper nigrum L. (Piperaceae) extract (PFPE) is a natural extract containing many types of antioxidants that may reduce Dox toxicities.
Jirakrit Saetang, Aman Tedasen, Surasak Sangkhathat, Natnaree Sangkaew, Sirinapa Dokduang, Napat Prompat, Siriporn Taraporn, Potchanapond Graidist   +7 more
doaj   +1 more source

Markers of Th1 polarized Th17 cells (literature review)

Acta Biomedica Scientifica, 2023
T helpers (Th) producing IL-17 (Th17) have high plasticity and under the influence of external conditions are able to redifferentiate into cells with a different phenotype, primarily in Th1-lymphocytes, forming a population that combines the ...
E. M. Kuklina, N. S. Glebezdina
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Serum Levels of Seven General Cytokines in Acute Brucellosis Before and After Treatment

Infection and Drug Resistance, 2021
Yunxia Tang,1,2,* Chenjie Ma,1,2,* Huali Sun,3 Siyuan Yang,1,2 Fengting Yu,1,2 Xingwang Li,1,2 Linghang Wang1,2 1Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Clinical Center for HIV/AIDS, Capital ...
Tang Y, Ma C, Sun H, Yang S, Yu F, Li X, Wang L   +6 more
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Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells' Differentiation and Function in Induction of Colitis.

Inflammatory Bowel Diseases, 2019
BACKGROUND How the gut microbiota regulates intestinal homeostasis is not completely clear. Gut microbiota metabolite short-chain fatty acids (SCFAs) have been reported to regulate T-cell differentiation.
Liang Chen, Mingming Sun, Wei Wu, Wenjing Yang, Xiangsheng Huang, Yi Xiao, Chunyan Ma, Leiqi Xu, Suxia Yao, Zhanju Liu, Y. Cong   +10 more
semanticscholar   +1 more source

Epigenetic silencing of Th1 type chemokines shapes tumor immunity and immunotherapy

Nature, 2015
Epigenetic silencing including histone modifications and DNA methylation is an important tumorigenic mechanism. However, its role in cancer immunopathology and immunotherapy is poorly understood.
D. Peng, Ilona Kryczek, N. Nagarsheth, Lili Zhao, Shuang Wei, Weimin Wang, Yuqing Sun, Ende Zhao, Linda Vatan, Wojciech Szeliga, J. Kotarski, R. Tarkowski, Y. Dou, Kathleen R. Cho, S. Hensley-Alford, A. Munkarah, Rebecca J Liu, W. Zou   +17 more
semanticscholar   +1 more source

Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria

Science immunology, 2017
Computational modeling defines T helper cell differentiation toward multiple fates during experimental malaria. Fork in the road for immune cells Immune cell differentiation along T helper pathways can profoundly influence the nature of the immune ...
Stuti Mehta, D. Cronkite, Megha Basavappa, Tahnee L. Saunders, Fatemeh Adiliaghdam, Hajera Amatullah, Sara A. Morrison, J. Pagan, Robert M. Anthony, P. Tonnerre, Georg M. Lauer, James C. Lee, Sreehaas Digumarthi, L. Pantano, Shannan J. Ho Sui, Fei Ji, Ruslan Sadreyev, Chan Zhou, Alan C. Mullen, Vinod Kumar, Yang Li, C. Wijmenga, Ramnik J. Xavier, Terry K. Means, Kate L. Jeffrey   +24 more
semanticscholar   +1 more source

TH1 cell-inducing Escherichia coli strain identified from the small intestinal mucosa of patients with Crohn’s disease

Gut Microbes, 2020
Dysbiotic microbiota contributes to the pathogenesis of Crohn’s disease (CD) by regulating the immune system. Although pro-inflammatory microbes are probably enriched in the small intestinal (SI) mucosa, most studies have focused on fecal microbiota ...
Manabu Nagayama, Tomonori Yano, Koji Atarashi, Takeshi Tanoue, Mariko Sekiya, Yasutoshi Kobayashi, Hirotsugu Sakamoto, Kouichi Miura, Keijiro Sunada, Takaaki Kawaguchi, Satoru Morita, Kayoko Sugita, Seiko Narushima, Nicolas Barnich, Jun Isayama, Yuko Kiridooshi, Atsushi Shiota, Wataru Suda, Masahira Hattori, Hironori Yamamoto, Kenya Honda   +20 more
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